Intraocular pressure responses to systemic autonomic stimulation in diabetes mellitus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-06

AUTHORS

L. P. Lanigan, C. V. Clark, J. Allawi, D. W. Hill, H. Keen

ABSTRACT

The acute changes in intraocular pressure during sustained handgrip contraction (2.5 minutes duration) and the Valsalva manoeuvre (15 seconds duration), both standard tests of autonomic nerve function were studied in 14 diabetic patients and 14 similar aged control subjects.During sustained handgrip contraction, diastolic blood pressure increased by 16.35 ± 1.87 mmHg in the diabetic patients and 21.36 ± 0.66 mmHg for the control group. Mean intraocular pressure decreased by 0.71 ± 0.43 mmHg in the diabetics, p < 0.05 and 0.64 ± 0.27 mmHg, p < 0.01) in the control group.There was no correlation between the blood pressure and the intraocular pressure responses in either group.On release of handgrip contraction, mean recovery intraocular pressure over 5 minutes was significantly lower than mean baseline values for the two groups; control: baseline 14.78 ± 0.49 to 14.14 ± 0.67, p < 0.001 and diabetic: 14.57 ± 0.65 to 13.86 ± 0.72, p < 0.001.During the Valsalva manoeuvre, there was a significant rise in intraocular pressure in the control (+7.85 ± 0.75mmHg, p < 0.001) and the diabetic group (+7.93 ± 1.18mmHg, p < 0.001). 5 minutes after release of intrathoracic pressure, mean recovery intraocular pressure remained significantly below baseline values for the two groups. The Valsalva ratios were in the normal range for the control group (1.21 to 2.2) while 2 diabetics had abnormal ratios. More... »

PAGES

141-153

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00156704

DOI

http://dx.doi.org/10.1007/bf00156704

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047918046

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2582995


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