Retroviruses View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2009

AUTHORS

Román Galetto , Matteo Negroni

ABSTRACT

Retroviruses are a large group of enveloped RNA viruses infecting vertebrates. The viral particles are spherical and acquire their envelope during budding from the infected cell. The lipid bilayer therefore contains cellular proteins as well as the viral envelope glycoproteins. These glycoproteins are constituted by a transmembrane subunit (TM) associated to the surface protein (SU), present on the virion. Underneath the membrane is a spherical shell constituted by the matrix (MA) protein. Internally is the viral capsid, whose shape varies in different viruses, constituted by the CA protein. This core contains the retroviral enzymes (the reverse transcriptase, RT, the integrase, IN, and the protease, PR), together with the genomic RNA, coated by the nucleocapsid protein (NC). More... »

PAGES

109-128

Book

TITLE

Viral Genome Replication

ISBN

978-0-387-89425-6
978-0-387-89456-0

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/b135974_6

DOI

http://dx.doi.org/10.1007/b135974_6

DIMENSIONS

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