Toxicological Study of Nanoparticles: An Attempt to Relate Physicochemical Characters with Toxicity View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2020-09-25

AUTHORS

A. Seenivasan , M. Muthuraj , T. Panda

ABSTRACT

Nanoparticles are being employed in numerous diverse fields of engineering and medicine attributed to their exclusive size and inherent physicochemical characteristics. The increased use of nanoparticles resulted in an unregulated environmental release and human exposures thereby prompting toxicological assessments and hazard analysis mandatory. With high frequency of nanoparticles in the market, incomplete assessments, hazard analysis and categorization remain the toughest job. Interestingly, the physicochemical properties are governing factors not only that determines utility, but also their toxicity. Thus, several attempts are being made to link the hazardous effect of particles with its physicochemical properties thereby reducing the experimental requirements. Moreover, it is mandatory to account mechanism of toxicity, which is still lagging. The present study reviews the physicochemical properties as cues to determine the toxicity of nanoparticles with possible mechanisms detailed. More... »

PAGES

325-342

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-981-15-5511-4_23

DOI

http://dx.doi.org/10.1007/978-981-15-5511-4_23

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1131167688


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