Changes in the Nuclear Envelope in Laminopathies. View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018

AUTHORS

Subarna Dutta , Maitree Bhattacharyya , Kaushik Sengupta

ABSTRACT

Double-membrane-bound nucleus is the major organelle of every metazoan cell, which controls various nuclear processes like chromatin maintenance, DNA replication, transcription and nucleoskeleton-cytoskeleton coupling. Nuclear homeostasis depends on the integrity of nuclear membrane and associated proteins. Lamins, underlying the inner nuclear membrane (INM), play a crucial role in maintaining nuclear homeostasis. In this review, we have focussed on the disruption of nuclear homeostasis due to lamin A/C mutation which produces a plethora of diseases, termed as laminopathies. More... »

PAGES

31-38

Book

TITLE

Biochemical and Biophysical Roles of Cell Surface Molecules

ISBN

978-981-13-3064-3
978-981-13-3065-0

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-981-13-3065-0_3

DOI

http://dx.doi.org/10.1007/978-981-13-3065-0_3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111389811

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30637688


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