Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2017-06-20

AUTHORS

Etsu Suzuki , Daishi Fujita , Masao Takahashi , Shigeyoshi Oba , Hiroaki Nishimatsu

ABSTRACT

Mesenchymal stem cells (MSCs) are multipotent stem cells that reside in various organs. They have the capacity to differentiate into various cell types, including cardiomyocytes, vascular endothelial cells, and vascular smooth muscle cells. Among the various MSCs, bone marrow-derived MSCs (BMMSCs) have been widely used for treating acute myocardial infarction (AMI) and ischemic heart failure (IHF) in preclinical and clinical studies. Although the beneficial effects of BMMSCs in treating AMI and IHF were originally attributed to their capacity to differentiate into cardiac cell types, recent evidence suggests that the differentiation capacity of BMMSCs appears to be minimal and that BMMSCs exert cardioprotective effects by secreting paracrine factors. In this context, MSC-derived exosomes have recently gained much attention. In this chapter, we introduce preclinical studies in which MSC-derived exosomes are used for treating cardiovascular diseases (CVDs) such as AMI, stroke, pulmonary hypertension, and septic cardiomyopathy. Future clinical studies are required to confirm the efficacy of exosome administration in treating CVDs. More... »

PAGES

179-185

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-981-10-4397-0_12

DOI

http://dx.doi.org/10.1007/978-981-10-4397-0_12

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091891112

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28936740


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cardiovascular Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exosomes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mesenchymal Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myocardium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myocytes, Cardiac", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recovery of Function", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Regeneration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, 216-8512, Kawasaki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412764.2", 
          "name": [
            "Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, 216-8512, Kawasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Etsu", 
        "id": "sg:person.01140123057.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140123057.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fujita", 
        "givenName": "Daishi", 
        "id": "sg:person.01150107730.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150107730.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takahashi", 
        "givenName": "Masao", 
        "id": "sg:person.013234515004.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013234515004.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oba", 
        "givenName": "Shigeyoshi", 
        "id": "sg:person.010260751664.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010260751664.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Medicine, The Department of Urology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Faculty of Medicine, The Department of Urology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishimatsu", 
        "givenName": "Hiroaki", 
        "id": "sg:person.0662043630.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662043630.06"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2017-06-20", 
    "datePublishedReg": "2017-06-20", 
    "description": "Mesenchymal stem cells (MSCs) are multipotent stem cells that reside in various organs. They have the capacity to differentiate into various cell types, including cardiomyocytes, vascular endothelial cells, and vascular smooth muscle cells. Among the various MSCs, bone marrow-derived MSCs (BMMSCs) have been widely used for treating acute myocardial infarction (AMI) and ischemic heart failure (IHF) in preclinical and clinical studies. Although the beneficial effects of BMMSCs in treating AMI and IHF were originally attributed to their capacity to differentiate into cardiac cell types, recent evidence suggests that the differentiation capacity of BMMSCs appears to be minimal and that BMMSCs exert cardioprotective effects by secreting paracrine factors. In this context, MSC-derived exosomes have recently gained much attention. In this chapter, we introduce preclinical studies in which MSC-derived exosomes are used for treating cardiovascular diseases (CVDs) such as AMI, stroke, pulmonary hypertension, and septic cardiomyopathy. Future clinical studies are required to confirm the efficacy of exosome administration in treating CVDs.", 
    "editor": [
      {
        "familyName": "Xiao", 
        "givenName": "Junjie", 
        "type": "Person"
      }, 
      {
        "familyName": "Cretoiu", 
        "givenName": "Sanda", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-981-10-4397-0_12", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-981-10-4396-3", 
        "978-981-10-4397-0"
      ], 
      "name": "Exosomes in Cardiovascular Diseases", 
      "type": "Book"
    }, 
    "keywords": [
      "mesenchymal stem cells", 
      "acute myocardial infarction", 
      "bone marrow-derived MSCs", 
      "ischemic heart failure", 
      "cardiovascular disease", 
      "stem cells", 
      "multipotent stem cells", 
      "clinical studies", 
      "vascular smooth muscle cells", 
      "mesenchymal stem cell-derived exosomes", 
      "bone marrow-derived mesenchymal stem cells", 
      "future clinical studies", 
      "marrow-derived mesenchymal stem cells", 
      "stem cell-derived exosomes", 
      "smooth muscle cells", 
      "cell-derived exosomes", 
      "differentiation capacity", 
      "vascular endothelial cells", 
      "septic cardiomyopathy", 
      "pulmonary hypertension", 
      "heart failure", 
      "cardioprotective effects", 
      "myocardial infarction", 
      "cell types", 
      "therapeutic effect", 
      "preclinical studies", 
      "cardiac cell types", 
      "paracrine factors", 
      "beneficial effects", 
      "muscle cells", 
      "endothelial cells", 
      "Recent evidence", 
      "disease", 
      "capacity", 
      "cells", 
      "exosomes", 
      "hypertension", 
      "infarction", 
      "cardiomyopathy", 
      "stroke", 
      "administration", 
      "study", 
      "efficacy", 
      "cardiomyocytes", 
      "effect", 
      "organs", 
      "failure", 
      "evidence", 
      "factors", 
      "types", 
      "attention", 
      "chapter", 
      "context"
    ], 
    "name": "Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease", 
    "pagination": "179-185", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091891112"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-981-10-4397-0_12"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28936740"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-981-10-4397-0_12", 
      "https://app.dimensions.ai/details/publication/pub.1091891112"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2021-11-01T18:50", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/chapter/chapter_202.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-981-10-4397-0_12"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-981-10-4397-0_12'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-981-10-4397-0_12'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-981-10-4397-0_12'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-981-10-4397-0_12'


 

This table displays all metadata directly associated to this object as RDF triples.

199 TRIPLES      23 PREDICATES      89 URIs      82 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-981-10-4397-0_12 schema:about N03594c56d48a4dafaf24d5279e8b56fc
2 N0a179054ecfd4b129a7fed6c1268c2c4
3 N10bcdbe97cb742489af49e07e28811ff
4 N2088a39916df44e8b54ee8b33272e9a6
5 N3d8254a903cd40a9ba58dc4cc401113e
6 N5826a23c99a4454da93ae21924daadee
7 Nc4d4980354e7434f9b652b0f50754031
8 Ncf294f86a8b642bebe834f327a3419ce
9 Nd7ffd523281d4cb78439aec09b8fbc2f
10 Ne60694dc64c4431dbd935bcaf03670a4
11 Nf8c7011d244e46a9afa2a826c980f77e
12 anzsrc-for:11
13 anzsrc-for:1102
14 schema:author N4c0fe6b7a8ad4c9bbb8c70585d51ec42
15 schema:datePublished 2017-06-20
16 schema:datePublishedReg 2017-06-20
17 schema:description Mesenchymal stem cells (MSCs) are multipotent stem cells that reside in various organs. They have the capacity to differentiate into various cell types, including cardiomyocytes, vascular endothelial cells, and vascular smooth muscle cells. Among the various MSCs, bone marrow-derived MSCs (BMMSCs) have been widely used for treating acute myocardial infarction (AMI) and ischemic heart failure (IHF) in preclinical and clinical studies. Although the beneficial effects of BMMSCs in treating AMI and IHF were originally attributed to their capacity to differentiate into cardiac cell types, recent evidence suggests that the differentiation capacity of BMMSCs appears to be minimal and that BMMSCs exert cardioprotective effects by secreting paracrine factors. In this context, MSC-derived exosomes have recently gained much attention. In this chapter, we introduce preclinical studies in which MSC-derived exosomes are used for treating cardiovascular diseases (CVDs) such as AMI, stroke, pulmonary hypertension, and septic cardiomyopathy. Future clinical studies are required to confirm the efficacy of exosome administration in treating CVDs.
18 schema:editor N600b3d634b774997be97b7121ebf57f2
19 schema:genre chapter
20 schema:inLanguage en
21 schema:isAccessibleForFree false
22 schema:isPartOf N7c433c9043ee4cd99b4ab8a8aa83c3bb
23 schema:keywords Recent evidence
24 acute myocardial infarction
25 administration
26 attention
27 beneficial effects
28 bone marrow-derived MSCs
29 bone marrow-derived mesenchymal stem cells
30 capacity
31 cardiac cell types
32 cardiomyocytes
33 cardiomyopathy
34 cardioprotective effects
35 cardiovascular disease
36 cell types
37 cell-derived exosomes
38 cells
39 chapter
40 clinical studies
41 context
42 differentiation capacity
43 disease
44 effect
45 efficacy
46 endothelial cells
47 evidence
48 exosomes
49 factors
50 failure
51 future clinical studies
52 heart failure
53 hypertension
54 infarction
55 ischemic heart failure
56 marrow-derived mesenchymal stem cells
57 mesenchymal stem cell-derived exosomes
58 mesenchymal stem cells
59 multipotent stem cells
60 muscle cells
61 myocardial infarction
62 organs
63 paracrine factors
64 preclinical studies
65 pulmonary hypertension
66 septic cardiomyopathy
67 smooth muscle cells
68 stem cell-derived exosomes
69 stem cells
70 stroke
71 study
72 therapeutic effect
73 types
74 vascular endothelial cells
75 vascular smooth muscle cells
76 schema:name Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease
77 schema:pagination 179-185
78 schema:productId Nb5d8a3a3f6b24d8d922d19731c78caf7
79 Ncf637acaf36c466eac235ab1ce2a0d29
80 Ne0b6f998c35d4af58a9208e4b6dd211d
81 schema:publisher N39ccb3462e874cceb69b3b8a7429f99e
82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091891112
83 https://doi.org/10.1007/978-981-10-4397-0_12
84 schema:sdDatePublished 2021-11-01T18:50
85 schema:sdLicense https://scigraph.springernature.com/explorer/license/
86 schema:sdPublisher N30410f20eea54288a6a136fffa13d6fe
87 schema:url https://doi.org/10.1007/978-981-10-4397-0_12
88 sgo:license sg:explorer/license/
89 sgo:sdDataset chapters
90 rdf:type schema:Chapter
91 N03594c56d48a4dafaf24d5279e8b56fc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Recovery of Function
93 rdf:type schema:DefinedTerm
94 N0a179054ecfd4b129a7fed6c1268c2c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Humans
96 rdf:type schema:DefinedTerm
97 N10bcdbe97cb742489af49e07e28811ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Signal Transduction
99 rdf:type schema:DefinedTerm
100 N2088a39916df44e8b54ee8b33272e9a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Myocytes, Cardiac
102 rdf:type schema:DefinedTerm
103 N22bde1baf1c146529e572dce5b8f51a2 schema:familyName Xiao
104 schema:givenName Junjie
105 rdf:type schema:Person
106 N30410f20eea54288a6a136fffa13d6fe schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N39ccb3462e874cceb69b3b8a7429f99e schema:name Springer Nature
109 rdf:type schema:Organisation
110 N3d8254a903cd40a9ba58dc4cc401113e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Animals
112 rdf:type schema:DefinedTerm
113 N4c0fe6b7a8ad4c9bbb8c70585d51ec42 rdf:first sg:person.01140123057.09
114 rdf:rest N7bdd8760f69f44b59b424b95dcc5b221
115 N5826a23c99a4454da93ae21924daadee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Regeneration
117 rdf:type schema:DefinedTerm
118 N600b3d634b774997be97b7121ebf57f2 rdf:first N22bde1baf1c146529e572dce5b8f51a2
119 rdf:rest N74160fca44ef4ddaa286d6cf90358a3a
120 N71979e19dc924a01845c4aa1d57031be rdf:first sg:person.013234515004.78
121 rdf:rest Nf8652100f84740cd923b6b81cba8b0e7
122 N74160fca44ef4ddaa286d6cf90358a3a rdf:first Nfc4fea733c0a488493bf6a3d5d639001
123 rdf:rest rdf:nil
124 N7bdd8760f69f44b59b424b95dcc5b221 rdf:first sg:person.01150107730.46
125 rdf:rest N71979e19dc924a01845c4aa1d57031be
126 N7c433c9043ee4cd99b4ab8a8aa83c3bb schema:isbn 978-981-10-4396-3
127 978-981-10-4397-0
128 schema:name Exosomes in Cardiovascular Diseases
129 rdf:type schema:Book
130 Nb5d8a3a3f6b24d8d922d19731c78caf7 schema:name doi
131 schema:value 10.1007/978-981-10-4397-0_12
132 rdf:type schema:PropertyValue
133 Nc4d4980354e7434f9b652b0f50754031 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Mesenchymal Stem Cell Transplantation
135 rdf:type schema:DefinedTerm
136 Ncf294f86a8b642bebe834f327a3419ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Myocardium
138 rdf:type schema:DefinedTerm
139 Ncf637acaf36c466eac235ab1ce2a0d29 schema:name pubmed_id
140 schema:value 28936740
141 rdf:type schema:PropertyValue
142 Nd7ffd523281d4cb78439aec09b8fbc2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Cardiovascular Diseases
144 rdf:type schema:DefinedTerm
145 Nda66f8f1f05147c082f72b6a55f845b2 rdf:first sg:person.0662043630.06
146 rdf:rest rdf:nil
147 Ne0b6f998c35d4af58a9208e4b6dd211d schema:name dimensions_id
148 schema:value pub.1091891112
149 rdf:type schema:PropertyValue
150 Ne60694dc64c4431dbd935bcaf03670a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Exosomes
152 rdf:type schema:DefinedTerm
153 Nf8652100f84740cd923b6b81cba8b0e7 rdf:first sg:person.010260751664.31
154 rdf:rest Nda66f8f1f05147c082f72b6a55f845b2
155 Nf8c7011d244e46a9afa2a826c980f77e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Gene Expression Regulation
157 rdf:type schema:DefinedTerm
158 Nfc4fea733c0a488493bf6a3d5d639001 schema:familyName Cretoiu
159 schema:givenName Sanda
160 rdf:type schema:Person
161 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
162 schema:name Medical and Health Sciences
163 rdf:type schema:DefinedTerm
164 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
165 schema:name Cardiorespiratory Medicine and Haematology
166 rdf:type schema:DefinedTerm
167 sg:person.010260751664.31 schema:affiliation grid-institutes:grid.26999.3d
168 schema:familyName Oba
169 schema:givenName Shigeyoshi
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010260751664.31
171 rdf:type schema:Person
172 sg:person.01140123057.09 schema:affiliation grid-institutes:grid.412764.2
173 schema:familyName Suzuki
174 schema:givenName Etsu
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140123057.09
176 rdf:type schema:Person
177 sg:person.01150107730.46 schema:affiliation grid-institutes:grid.26999.3d
178 schema:familyName Fujita
179 schema:givenName Daishi
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150107730.46
181 rdf:type schema:Person
182 sg:person.013234515004.78 schema:affiliation grid-institutes:grid.26999.3d
183 schema:familyName Takahashi
184 schema:givenName Masao
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013234515004.78
186 rdf:type schema:Person
187 sg:person.0662043630.06 schema:affiliation grid-institutes:grid.26999.3d
188 schema:familyName Nishimatsu
189 schema:givenName Hiroaki
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662043630.06
191 rdf:type schema:Person
192 grid-institutes:grid.26999.3d schema:alternateName Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
193 Faculty of Medicine, The Department of Urology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
194 schema:name Faculty of Medicine, The Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
195 Faculty of Medicine, The Department of Urology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
196 rdf:type schema:Organization
197 grid-institutes:grid.412764.2 schema:alternateName Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, 216-8512, Kawasaki, Japan
198 schema:name Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, 216-8512, Kawasaki, Japan
199 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...