Role of interleukin-1 beta and other potential genetic markers as indicators of gastric cancer risk View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2003

AUTHORS

E. Troost , G. L. Hold , M. Smith , W.-H. Chow , C. S. Rabkin , K. E. L. McColl , E. M. El-Omar

ABSTRACT

It has long been established that human susceptibility to infectious agents is at least partly under genetic control. Several observations from twin, adoptee, pedigree, and candidate gene studies point to host genetic factors as key determinants of this susceptibility1,2. The recent explosion in genetic knowledge, accelerated by the human genome project, is helping to unravel the molecular pathways that mediate genetic susceptibility to human diseases, including infections and cancer3–5. While genetic susceptibility may apply to the risk of acquisition of an infectious agent, it is becoming increasingly recognized that host genes also influence the pathophysiological response to infections, which ultimately determine the clinical outcome. More... »

PAGES

215-223

Book

TITLE

Helicobactor pylori

ISBN

978-90-481-5778-5
978-94-017-1763-2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-94-017-1763-2_22

DOI

http://dx.doi.org/10.1007/978-94-017-1763-2_22

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012690249


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