Deoxyspergualin. A novel immunosuppressant: experimental and clinical studies View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1991

AUTHORS

H. Amemiya , S. Suzuki , K. Ota , K. Takahashi , T. Sonoda , M. Ishibashi , R. Omoto , I. Koyama , K. Dohi , Y. Fukuda , K. Fukao

ABSTRACT

Deoxyspergualin (DSG) is an analogue of an antibiotic having antitumor effect, spergualin (1), which was isolated from the culture filtrate of Bacillus laterosporus in 1981. In 1985, it was reported that DSG had immunosuppressive effect (2, 3), and thereafter the characteristics of the agent as an immunosuppressant against rejection has been examined in detail. Figure 1 shows the chemical structure of DSG, which has a molecular weight of 496.91, occurs as white powder, and is very soluble in water and stable for a long period at 15 °C and below. More... »

PAGES

123-127

Book

TITLE

Organ Transplantation 1990

ISBN

978-94-010-5497-3
978-94-011-3386-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-94-011-3386-9_16

DOI

http://dx.doi.org/10.1007/978-94-011-3386-9_16

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007178718


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