The pheromone signal pathway in Saccharomyces cerevisiae View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1992

AUTHORS

James B. Konopka , Stanley Fields

ABSTRACT

Haploid cells of the yeast Saccharomyces cerevisiae normally undergo a budding life cycle, but after binding the appropriate mating pheromone they undergo a different developmental pathway that leads to conjugation. This intercellular communication between the two mating types activates a signal transduction pathway that stimulates the diverse physiological changes required for conjugation, such as induction of cell surface agglutinins, cell division arrest in Gl, morphogenesis to form a conjugation tube, and cell fusion. The components of this pathway include a G protein-coupled receptor, several protein kinases, and a phero-mone-responsive transcription factor. The molecular mechanisms that transduce the pheromone signal are remarkably similar to the mechanisms of hormone signaling used in multicellular organisms. Thus, the analysis of the pheromone signal pathway in yeast directly contributes to the study of cell growth and development in other eukaryotic organisms. More... »

PAGES

95-108

Book

TITLE

Molecular Biology of Saccharomyces

ISBN

978-94-010-5104-0
978-94-011-2504-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-94-011-2504-8_8

DOI

http://dx.doi.org/10.1007/978-94-011-2504-8_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037170097


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.36425.36", 
          "name": [
            "Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Konopka", 
        "givenName": "James B.", 
        "id": "sg:person.0672737144.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672737144.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.36425.36", 
          "name": [
            "Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fields", 
        "givenName": "Stanley", 
        "id": "sg:person.014624417057.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014624417057.73"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1992", 
    "datePublishedReg": "1992-01-01", 
    "description": "Haploid cells of the yeast Saccharomyces cerevisiae normally undergo a budding life cycle, but after binding the appropriate mating pheromone they undergo a different developmental pathway that leads to conjugation. This intercellular communication between the two mating types activates a signal transduction pathway that stimulates the diverse physiological changes required for conjugation, such as induction of cell surface agglutinins, cell division arrest in Gl, morphogenesis to form a conjugation tube, and cell fusion. The components of this pathway include a G protein-coupled receptor, several protein kinases, and a phero-mone-responsive transcription factor. The molecular mechanisms that transduce the pheromone signal are remarkably similar to the mechanisms of hormone signaling used in multicellular organisms. Thus, the analysis of the pheromone signal pathway in yeast directly contributes to the study of cell growth and development in other eukaryotic organisms.", 
    "editor": [
      {
        "familyName": "Grivell", 
        "givenName": "L. A.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-94-011-2504-8_8", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-94-010-5104-0", 
        "978-94-011-2504-8"
      ], 
      "name": "Molecular Biology of Saccharomyces", 
      "type": "Book"
    }, 
    "keywords": [
      "pheromone-signaling pathway", 
      "appropriate mating pheromone", 
      "cell division arrest", 
      "responsive transcription factors", 
      "signal pathway", 
      "signal transduction pathways", 
      "G protein-coupled receptors", 
      "cell surface agglutinins", 
      "protein-coupled receptors", 
      "mechanism of hormone", 
      "different developmental pathways", 
      "multicellular organisms", 
      "eukaryotic organisms", 
      "mating pheromone", 
      "diverse physiological changes", 
      "division arrest", 
      "yeast Saccharomyces", 
      "haploid cells", 
      "pheromone signals", 
      "transcription factors", 
      "transduction pathways", 
      "protein kinase", 
      "mating types", 
      "conjugation tubes", 
      "molecular mechanisms", 
      "developmental pathways", 
      "intercellular communication", 
      "cell fusion", 
      "cell growth", 
      "Saccharomyces", 
      "pathway", 
      "life cycle", 
      "organisms", 
      "physiological changes", 
      "morphogenesis", 
      "kinase", 
      "yeast", 
      "pheromone", 
      "mechanism", 
      "cells", 
      "induction", 
      "arrest", 
      "conjugation", 
      "receptors", 
      "growth", 
      "fusion", 
      "agglutinin", 
      "hormone", 
      "cycle", 
      "GL", 
      "signals", 
      "development", 
      "components", 
      "changes", 
      "factors", 
      "analysis", 
      "types", 
      "study", 
      "tube", 
      "communication"
    ], 
    "name": "The pheromone signal pathway in Saccharomyces cerevisiae", 
    "pagination": "95-108", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037170097"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-94-011-2504-8_8"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-94-011-2504-8_8", 
      "https://app.dimensions.ai/details/publication/pub.1037170097"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-11-24T21:15", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/chapter/chapter_274.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-94-011-2504-8_8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-94-011-2504-8_8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-94-011-2504-8_8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-94-011-2504-8_8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-94-011-2504-8_8'


 

This table displays all metadata directly associated to this object as RDF triples.

126 TRIPLES      22 PREDICATES      85 URIs      78 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-94-011-2504-8_8 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N170153605aec4c55841e462420f162c7
4 schema:datePublished 1992
5 schema:datePublishedReg 1992-01-01
6 schema:description Haploid cells of the yeast Saccharomyces cerevisiae normally undergo a budding life cycle, but after binding the appropriate mating pheromone they undergo a different developmental pathway that leads to conjugation. This intercellular communication between the two mating types activates a signal transduction pathway that stimulates the diverse physiological changes required for conjugation, such as induction of cell surface agglutinins, cell division arrest in Gl, morphogenesis to form a conjugation tube, and cell fusion. The components of this pathway include a G protein-coupled receptor, several protein kinases, and a phero-mone-responsive transcription factor. The molecular mechanisms that transduce the pheromone signal are remarkably similar to the mechanisms of hormone signaling used in multicellular organisms. Thus, the analysis of the pheromone signal pathway in yeast directly contributes to the study of cell growth and development in other eukaryotic organisms.
7 schema:editor N1133fc43c48848c79333bee92d0bb60a
8 schema:genre chapter
9 schema:isAccessibleForFree false
10 schema:isPartOf Ndef70203f6214034afd93e6adfc00c40
11 schema:keywords G protein-coupled receptors
12 GL
13 Saccharomyces
14 agglutinin
15 analysis
16 appropriate mating pheromone
17 arrest
18 cell division arrest
19 cell fusion
20 cell growth
21 cell surface agglutinins
22 cells
23 changes
24 communication
25 components
26 conjugation
27 conjugation tubes
28 cycle
29 development
30 developmental pathways
31 different developmental pathways
32 diverse physiological changes
33 division arrest
34 eukaryotic organisms
35 factors
36 fusion
37 growth
38 haploid cells
39 hormone
40 induction
41 intercellular communication
42 kinase
43 life cycle
44 mating pheromone
45 mating types
46 mechanism
47 mechanism of hormone
48 molecular mechanisms
49 morphogenesis
50 multicellular organisms
51 organisms
52 pathway
53 pheromone
54 pheromone signals
55 pheromone-signaling pathway
56 physiological changes
57 protein kinase
58 protein-coupled receptors
59 receptors
60 responsive transcription factors
61 signal pathway
62 signal transduction pathways
63 signals
64 study
65 transcription factors
66 transduction pathways
67 tube
68 types
69 yeast
70 yeast Saccharomyces
71 schema:name The pheromone signal pathway in Saccharomyces cerevisiae
72 schema:pagination 95-108
73 schema:productId N17e3c07fc61743cea0ce135b8885e615
74 N37bcc22e229344978b71de414f70f316
75 schema:publisher N45658b2900474f268f5691d37e088982
76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037170097
77 https://doi.org/10.1007/978-94-011-2504-8_8
78 schema:sdDatePublished 2022-11-24T21:15
79 schema:sdLicense https://scigraph.springernature.com/explorer/license/
80 schema:sdPublisher N16aa9f050df543ebaa9517bf975e33f6
81 schema:url https://doi.org/10.1007/978-94-011-2504-8_8
82 sgo:license sg:explorer/license/
83 sgo:sdDataset chapters
84 rdf:type schema:Chapter
85 N1133fc43c48848c79333bee92d0bb60a rdf:first N57d601da203b4f9b9dfedec6fcd9c05c
86 rdf:rest rdf:nil
87 N16aa9f050df543ebaa9517bf975e33f6 schema:name Springer Nature - SN SciGraph project
88 rdf:type schema:Organization
89 N170153605aec4c55841e462420f162c7 rdf:first sg:person.0672737144.07
90 rdf:rest N7c6074aef8734e3b956ed67b8046e0dd
91 N17e3c07fc61743cea0ce135b8885e615 schema:name doi
92 schema:value 10.1007/978-94-011-2504-8_8
93 rdf:type schema:PropertyValue
94 N37bcc22e229344978b71de414f70f316 schema:name dimensions_id
95 schema:value pub.1037170097
96 rdf:type schema:PropertyValue
97 N45658b2900474f268f5691d37e088982 schema:name Springer Nature
98 rdf:type schema:Organisation
99 N57d601da203b4f9b9dfedec6fcd9c05c schema:familyName Grivell
100 schema:givenName L. A.
101 rdf:type schema:Person
102 N7c6074aef8734e3b956ed67b8046e0dd rdf:first sg:person.014624417057.73
103 rdf:rest rdf:nil
104 Ndef70203f6214034afd93e6adfc00c40 schema:isbn 978-94-010-5104-0
105 978-94-011-2504-8
106 schema:name Molecular Biology of Saccharomyces
107 rdf:type schema:Book
108 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
109 schema:name Biological Sciences
110 rdf:type schema:DefinedTerm
111 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
112 schema:name Biochemistry and Cell Biology
113 rdf:type schema:DefinedTerm
114 sg:person.014624417057.73 schema:affiliation grid-institutes:grid.36425.36
115 schema:familyName Fields
116 schema:givenName Stanley
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014624417057.73
118 rdf:type schema:Person
119 sg:person.0672737144.07 schema:affiliation grid-institutes:grid.36425.36
120 schema:familyName Konopka
121 schema:givenName James B.
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672737144.07
123 rdf:type schema:Person
124 grid-institutes:grid.36425.36 schema:alternateName Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA
125 schema:name Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA
126 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...