1994
AUTHORSMarjori Matzke , Antonius J. M. Matzke , Ortrun Mittelsten Scheid
ABSTRACTHomology-dependent gene silencing, in which the presence of two or more totally or partially homologous copies of a nuclear gene can lead to inactivation of at least one gene copy, has provided a fresh perspective for understanding fundamental aspects of gene expression in plants. Several reviews have appeared recently on this topic (Matzke & Matzke 1993a, 1993b; Jorgensen 1992b, 1993), and various possible mechanisms have been proposed. Our aim is not to duplicate these previous reviews, but to consider one specific hypothetical mechanism that involves the recognition and pairing of homologous DNA sequences in somatic cells, followed by the transmission of epigenetic information between these regions. As should be immediately evident, the initiating steps of this mechanism — homology sensing and pairing — can be common to gene inactivation and homologous recombination. Therefore, we regard homology-dependent gene silencing as an integral part of a discussion on homologous recombination in plants. More... »
PAGES271-307
Homologous Recombination and Gene Silencing in Plants
ISBN
978-94-010-4478-3
978-94-011-1094-5
http://scigraph.springernature.com/pub.10.1007/978-94-011-1094-5_12
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