Radiohalogenated L-α-Methyltyrosines as Potential Pancreas Imaging Agents for PECT and SPECT View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1982

AUTHORS

G. Kloster , H. H. Coenen , Z. Szabo , F. Ritzl , G. Stöcklin

ABSTRACT

The diagnosis of pancreatic carcinoma is still a problem in nuclar medicine (1), and an improved pancreas imaging agent is urgently needed. Currently, L-I75Se)-seleno-methionine (SM) is used as an agent for the detection of pancreatic carcinoma (2), with 99mTc sulfur colloid often injected in addition in order to permit the substraction of the interfering liver back-ground from SM (3). This imaging procedure results in rather large radiation doses to the patient, especially since the biological half-time of SM (70 days) is comparable with the physical half-life (120 days) of 75Se (4). Additionally, significant numbers of false-positives and false-negatives make routine diagnosis difficult (5). More... »

PAGES

97-107

References to SciGraph publications

  • 1979-05. Accumulation of radioiodinated tyrosine derivatives in the adrenal medulla and in melanomas in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1976-03. Labelling and metabolism of methionine-methyl-11C in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1977-12. Fully automatic computer-assisted pancreas imaging in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Book

    TITLE

    Progress in Radiopharmacology 3

    ISBN

    978-94-009-7671-9
    978-94-009-7669-6

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-94-009-7669-6_12

    DOI

    http://dx.doi.org/10.1007/978-94-009-7669-6_12

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1036582811


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