Abstracts of the First Meeting of the Society for Intestinal Microbial Ecology and Disease, Boston, Massachusetts, 1983 View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1984

AUTHORS

Jeanette Winter , Victor D. Bokkenheuser , Michael Stek , Charles E. Edmiston , A. S. Soerjadi-Liem , G. H. Snoeyenbos , O. M. Weinack , C. E. Nord , R. Bennet , M. Eriksson , R. Zetterstrom , Yoshimi Benno , Ken Sawade , Tomotari Mitsuoka , Kunihiko Suzuki , Hiroshi Hirakawa , Nobuo Hiwatashi , Akio Nagasaki , Yosio Goto , G. L. Larsen , J. E. Bakke , M. J. Allison , H. M. Cook , C. A. Thorne , R. V. Clayman , C. Pothoulakie , N. Wedel , C. Franzblau , J. T. LaMont , Gray Weaver , Meyer J. Wolin , Terry L. Miller , Lindsey R. Inman , J. Robert Cantey , K. H. Wilson , J. N. Sheagren , R. Freter , H. M. Cowley , R. R. H. Hill , S. P. Borriello , K. D. R. Setchell , Fiona Barclay , K. Ramotar , J. Conly , E. Bow , A. Ronald , T. J. Louie , R. J. Carman , S. P. Borriello , A. B. Price

ABSTRACT

During enterohepatic circulation conjugated steroids are hydrolyzed by intestinal bacteria, further metabolized mainly by anaerobic bacteria, reabsorbed, reconjugated and delivered to the blood for renal excretion. 21-Dehydroxlylation of tetrahydrodeoxycorticosterone (THCOD) to pregnanolone is performed exclusively by Eubacterium lentum, a normal inhabitant of the intestinal flora. The concentration of E. lentum in feces can be determined from the highest dilution of fresh voided stool capable of 21-dehydroxylating THDOC. Such studies revealed that the concentration increases from 106/g wet feces during the first year of life to 108/g feces in the 7th and 8th decade. Colonization appears to be independent of diet since the organisms are present in babies whether breast-fed or on formula, in subjects on a “Western diet” and in Africans consuming a diet low in meat and fat. More... »

PAGES

263-287

Book

TITLE

Models of Anaerobic Infection

ISBN

978-94-009-6056-5
978-94-009-6054-1

Author Affiliations

  • St. Luke’s — Roosevelt Hospital Center, 10025, New York, NY, USA
  • Division of Tropical Public Health, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, 20814, Bethesda, Maryland, USA
  • Allied Health Discipline, University of Wisconsin-Parkside, 53141, Kenosha, WI, USA
  • Department of Veterinary and Animal Sciences, University of Massachusets, 01003, Ameherst, Massachusetts, USA
  • Department of Pediatrics, St. Goran’s Children’s Hospital, Department of Microbiology, Huddinge University Hospital, Karolinska Institute, and National Bacteriological Laboratory, Stockholm, Sweden
  • The Institute of Physical and Chemical Research, Wako, Saitama, 351, Japan
  • Department of Pediatriacs, Toho University School of Medicine, Ohota-ku, Toxyo, 143, Japan
  • Department of Biomedical Science, Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan
  • The Third Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan
  • USDA, ARS, Metabolism and Radiation Research Lab., 58105, Fargo, N. D., USA
  • National animal Disease Centre, ARS, USDA, 50010, Amea, IA, USA
  • V.A. Medical Center, 55417, Minneapolis, MN, USA
  • Evans Department of Clinical Research, Section of Gastroenterology and Department of Biochemistry, Boston Univeristy School of Medicine, 02118, Boston, MA, USA
  • New York State Health Department, Albany, NY, USA
  • Veterans Administration Medical Center, 29403, Charleston, SC, USA
  • Department of Immunology, University of Michigan Medical School, Ann Arbor, MI, USA
  • Department of Infectious Diseases, University of Witwatersand, 1, Jan Smuts Avenue, Braafontein, 2001, Johannesburg, South Africa
  • Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, UK
  • University of Manitoba, Winnipeg, Canada
  • Charing Cross Hospital Medical School, St.Dunstanfs Road, W6 8RP, London, England
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-94-009-6054-1_22

    DOI

    http://dx.doi.org/10.1007/978-94-009-6054-1_22

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1041531318


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