Interleukin 1β production by colonic mucosa from children with Crohn’s disease View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1990

AUTHORS

S M Hill , P J Milla , G F Bottazzo , R Mirakian

ABSTRACT

Crohn’s disease is a chronic relapsing inflammatory disorder involving the bowel, of unknown aetiology. The disease process involves abnormal cellular and humoral immunological mechanisms (1) and the affected mucosa is infiltrated by inflammatory cells. IL-1β is important as a mediator of inflammation and initiator of the immune response (2). The aim of this study was to investigate IL-1 β production by colonic mucosa taken from children with CD, and compare this with production by control tissue both under basal culture conditions, and after stimulation with lipopolysaccharide (LPS). More... »

PAGES

715-716

References to SciGraph publications

  • 1988-02. News and notices in DIGESTIVE DISEASES AND SCIENCES
  • Book

    TITLE

    Advances in Mucosal Immunology

    ISBN

    978-94-010-7323-3
    978-94-009-1848-1

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-94-009-1848-1_220

    DOI

    http://dx.doi.org/10.1007/978-94-009-1848-1_220

    DIMENSIONS

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