Influence of CsA on humoral immunity and on B lymphocyte activation View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1989

AUTHORS

Iris Motta , Paolo Truffa-Bachi

ABSTRACT

CsA is a hydrophobic cyclic undecapeptïde of fungal origin with potent specific immunosuppressive effects in vivo and in vitro. Since its discovery by Borel and his group in 19761, CsA has proved an effective and valuable agent for suppression of allograft rejection in animals and has found widespread clinical acceptance2,3. CsA is highly specific for lymphocytes and this property suggested that these cells possess some unique features of growth control which might be unravelled through an understanding of the CsA mode of action. Consequently, many laboratories have investigated the effect of this drug on lymphocyte stimulation by antigens or by polyclonal mitogenic or non-mitogenic B cell activators. More... »

PAGES

34-49

Book

TITLE

Cyclosporin

ISBN

978-94-010-6874-1
978-94-009-0859-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-94-009-0859-8_3

DOI

http://dx.doi.org/10.1007/978-94-009-0859-8_3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007454831


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Motta", 
        "givenName": "Iris", 
        "id": "sg:person.0674650317.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674650317.92"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Truffa-Bachi", 
        "givenName": "Paolo", 
        "id": "sg:person.070474653.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.070474653.50"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.77.3.1612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000399504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0192-0561(84)90037-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002047449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0192-0561(84)90037-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002047449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-5699(82)90095-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004749611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0769-2625(87)80135-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005479594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.148.6.1628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006102264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.iy.03.040185.002145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008257972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.1830121013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010013338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.iy.01.040183.001235", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011542964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio237015a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011836543", 
          "https://doi.org/10.1038/newbio237015a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio237015a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011836543", 
          "https://doi.org/10.1038/newbio237015a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio237015a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011836543", 
          "https://doi.org/10.1038/newbio237015a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.1830170222", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012594950"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.1830140308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014513663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/289300a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015730683", 
          "https://doi.org/10.1038/289300a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/287542a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019146409", 
          "https://doi.org/10.1038/287542a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.160.3.679", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019761424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0769-2625(84)81188-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023189298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007890-197901000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025002301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007890-197901000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025002301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-5699(88)91259-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025339056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-5699(88)91259-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025339056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.150.6.1339", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026171464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-065x.1982.tb00421.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026387599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-065x.1982.tb00425.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026623127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.83.2.437", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028463371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-065x.1982.tb00423.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030491752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.iy.06.040188.002413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031117624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-5699(85)90061-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032924641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.155.5.1523", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033456611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3083.1985.tb01864.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033807783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-065x.1980.tb00333.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034408147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0008-8749(86)90310-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036696523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3083.1983.tb00787.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037378189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.1830140309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037843516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0008-8749(84)90032-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039871900"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0769-2617(87)80001-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040047009"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.1830130503", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041243853"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.158.3.690", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042680401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.156.6.1821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043120328"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.157.2.530", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043399270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(85)80080-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043529825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0769-2625(85)80003-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046667458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00915009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048497807", 
          "https://doi.org/10.1007/bf00915009"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3083.1979.tb03278.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049417407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.83.8.2599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049434492"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.iy.01.040183.001515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049622973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0008-8749(87)90281-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050129738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.1830121207", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050566375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.iy.05.040187.001135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050851818"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01973261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051012626", 
          "https://doi.org/10.1007/bf01973261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0008-8749(85)90096-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051829561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-5699(86)90148-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051858058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-2478(86)90051-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053018297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-2478(86)90051-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053018297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074659988", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078801513", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078816691", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078821976", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079060168", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079466529", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079493304", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079501223", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079503499", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079508372", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079551536", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079555331", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079661323", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079778816", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079780797", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079796708", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079954327", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jlb.38.2.231", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080008436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081595379", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081657839", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081671655", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081681407", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081684446", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081978855", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082077440", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082127306", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1989", 
    "datePublishedReg": "1989-01-01", 
    "description": "CsA is a hydrophobic cyclic undecapept\u00efde of fungal origin with potent specific immunosuppressive effects in vivo and in vitro. Since its discovery by Borel and his group in 19761, CsA has proved an effective and valuable agent for suppression of allograft rejection in animals and has found widespread clinical acceptance2,3. CsA is highly specific for lymphocytes and this property suggested that these cells possess some unique features of growth control which might be unravelled through an understanding of the CsA mode of action. Consequently, many laboratories have investigated the effect of this drug on lymphocyte stimulation by antigens or by polyclonal mitogenic or non-mitogenic B cell activators.", 
    "editor": [
      {
        "familyName": "Thomson", 
        "givenName": "Angus W.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-94-009-0859-8_3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-94-010-6874-1", 
        "978-94-009-0859-8"
      ], 
      "name": "Cyclosporin", 
      "type": "Book"
    }, 
    "name": "Influence of CsA on humoral immunity and on B lymphocyte activation", 
    "pagination": "34-49", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1007454831"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-94-009-0859-8_3"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "238238a39365b20eb2bb4a1edcfd0bf4ca0d31ab4a4e91f5a439242dcba86e6c"
        ]
      }
    ], 
    "publisher": {
      "location": "Dordrecht", 
      "name": "Springer Netherlands", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-94-009-0859-8_3", 
      "https://app.dimensions.ai/details/publication/pub.1007454831"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-16T09:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130830_00000000.jsonl", 
    "type": "Chapter", 
    "url": "https://link.springer.com/10.1007%2F978-94-009-0859-8_3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-94-009-0859-8_3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-94-009-0859-8_3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-94-009-0859-8_3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-94-009-0859-8_3'


 

This table displays all metadata directly associated to this object as RDF triples.

272 TRIPLES      23 PREDICATES      102 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-94-009-0859-8_3 schema:about anzsrc-for:11
2 anzsrc-for:1107
3 schema:author Neca4a6d6a97d489096e88a95641629cf
4 schema:citation sg:pub.10.1007/bf00915009
5 sg:pub.10.1007/bf01973261
6 sg:pub.10.1038/287542a0
7 sg:pub.10.1038/289300a0
8 sg:pub.10.1038/newbio237015a0
9 https://app.dimensions.ai/details/publication/pub.1074659988
10 https://app.dimensions.ai/details/publication/pub.1078801513
11 https://app.dimensions.ai/details/publication/pub.1078816691
12 https://app.dimensions.ai/details/publication/pub.1078821976
13 https://app.dimensions.ai/details/publication/pub.1079060168
14 https://app.dimensions.ai/details/publication/pub.1079466529
15 https://app.dimensions.ai/details/publication/pub.1079493304
16 https://app.dimensions.ai/details/publication/pub.1079501223
17 https://app.dimensions.ai/details/publication/pub.1079503499
18 https://app.dimensions.ai/details/publication/pub.1079508372
19 https://app.dimensions.ai/details/publication/pub.1079551536
20 https://app.dimensions.ai/details/publication/pub.1079555331
21 https://app.dimensions.ai/details/publication/pub.1079661323
22 https://app.dimensions.ai/details/publication/pub.1079778816
23 https://app.dimensions.ai/details/publication/pub.1079780797
24 https://app.dimensions.ai/details/publication/pub.1079796708
25 https://app.dimensions.ai/details/publication/pub.1079954327
26 https://app.dimensions.ai/details/publication/pub.1081595379
27 https://app.dimensions.ai/details/publication/pub.1081657839
28 https://app.dimensions.ai/details/publication/pub.1081671655
29 https://app.dimensions.ai/details/publication/pub.1081681407
30 https://app.dimensions.ai/details/publication/pub.1081684446
31 https://app.dimensions.ai/details/publication/pub.1081978855
32 https://app.dimensions.ai/details/publication/pub.1082077440
33 https://app.dimensions.ai/details/publication/pub.1082127306
34 https://doi.org/10.1002/eji.1830121013
35 https://doi.org/10.1002/eji.1830121207
36 https://doi.org/10.1002/eji.1830130503
37 https://doi.org/10.1002/eji.1830140308
38 https://doi.org/10.1002/eji.1830140309
39 https://doi.org/10.1002/eji.1830170222
40 https://doi.org/10.1002/jlb.38.2.231
41 https://doi.org/10.1016/0008-8749(84)90032-7
42 https://doi.org/10.1016/0008-8749(85)90096-6
43 https://doi.org/10.1016/0008-8749(86)90310-2
44 https://doi.org/10.1016/0008-8749(87)90281-4
45 https://doi.org/10.1016/0165-2478(86)90051-9
46 https://doi.org/10.1016/0167-5699(82)90095-0
47 https://doi.org/10.1016/0167-5699(85)90061-1
48 https://doi.org/10.1016/0167-5699(86)90148-9
49 https://doi.org/10.1016/0167-5699(88)91259-5
50 https://doi.org/10.1016/0192-0561(84)90037-7
51 https://doi.org/10.1016/s0092-8674(85)80080-5
52 https://doi.org/10.1016/s0769-2617(87)80001-1
53 https://doi.org/10.1016/s0769-2625(84)81188-5
54 https://doi.org/10.1016/s0769-2625(85)80003-9
55 https://doi.org/10.1016/s0769-2625(87)80135-6
56 https://doi.org/10.1073/pnas.77.3.1612
57 https://doi.org/10.1073/pnas.83.2.437
58 https://doi.org/10.1073/pnas.83.8.2599
59 https://doi.org/10.1084/jem.148.6.1628
60 https://doi.org/10.1084/jem.150.6.1339
61 https://doi.org/10.1084/jem.155.5.1523
62 https://doi.org/10.1084/jem.156.6.1821
63 https://doi.org/10.1084/jem.157.2.530
64 https://doi.org/10.1084/jem.158.3.690
65 https://doi.org/10.1084/jem.160.3.679
66 https://doi.org/10.1097/00007890-197901000-00014
67 https://doi.org/10.1111/j.1365-3083.1979.tb03278.x
68 https://doi.org/10.1111/j.1365-3083.1983.tb00787.x
69 https://doi.org/10.1111/j.1365-3083.1985.tb01864.x
70 https://doi.org/10.1111/j.1600-065x.1980.tb00333.x
71 https://doi.org/10.1111/j.1600-065x.1982.tb00421.x
72 https://doi.org/10.1111/j.1600-065x.1982.tb00423.x
73 https://doi.org/10.1111/j.1600-065x.1982.tb00425.x
74 https://doi.org/10.1146/annurev.iy.01.040183.001235
75 https://doi.org/10.1146/annurev.iy.01.040183.001515
76 https://doi.org/10.1146/annurev.iy.03.040185.002145
77 https://doi.org/10.1146/annurev.iy.05.040187.001135
78 https://doi.org/10.1146/annurev.iy.06.040188.002413
79 schema:datePublished 1989
80 schema:datePublishedReg 1989-01-01
81 schema:description CsA is a hydrophobic cyclic undecapeptïde of fungal origin with potent specific immunosuppressive effects in vivo and in vitro. Since its discovery by Borel and his group in 19761, CsA has proved an effective and valuable agent for suppression of allograft rejection in animals and has found widespread clinical acceptance2,3. CsA is highly specific for lymphocytes and this property suggested that these cells possess some unique features of growth control which might be unravelled through an understanding of the CsA mode of action. Consequently, many laboratories have investigated the effect of this drug on lymphocyte stimulation by antigens or by polyclonal mitogenic or non-mitogenic B cell activators.
82 schema:editor Nedd984d13f1b4bb2b359aa5179891469
83 schema:genre chapter
84 schema:inLanguage en
85 schema:isAccessibleForFree false
86 schema:isPartOf N941d5c1d7d314c94b35c08bb2ad0eb99
87 schema:name Influence of CsA on humoral immunity and on B lymphocyte activation
88 schema:pagination 34-49
89 schema:productId N19e1b7c2869842dda179a403bb518563
90 N2847a7dd64984a4dabb048578be2dad1
91 N93311a8fbb9b427eb35309e7b204bacf
92 schema:publisher Nec24c7db9cc641da8bbd5a31e4e55256
93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007454831
94 https://doi.org/10.1007/978-94-009-0859-8_3
95 schema:sdDatePublished 2019-04-16T09:21
96 schema:sdLicense https://scigraph.springernature.com/explorer/license/
97 schema:sdPublisher Nabb982c3df5b46758d07efc44af3ffa7
98 schema:url https://link.springer.com/10.1007%2F978-94-009-0859-8_3
99 sgo:license sg:explorer/license/
100 sgo:sdDataset chapters
101 rdf:type schema:Chapter
102 N0161e3b68fee4f67acc89130a579578c schema:familyName Thomson
103 schema:givenName Angus W.
104 rdf:type schema:Person
105 N19e1b7c2869842dda179a403bb518563 schema:name readcube_id
106 schema:value 238238a39365b20eb2bb4a1edcfd0bf4ca0d31ab4a4e91f5a439242dcba86e6c
107 rdf:type schema:PropertyValue
108 N2847a7dd64984a4dabb048578be2dad1 schema:name dimensions_id
109 schema:value pub.1007454831
110 rdf:type schema:PropertyValue
111 N93311a8fbb9b427eb35309e7b204bacf schema:name doi
112 schema:value 10.1007/978-94-009-0859-8_3
113 rdf:type schema:PropertyValue
114 N941d5c1d7d314c94b35c08bb2ad0eb99 schema:isbn 978-94-009-0859-8
115 978-94-010-6874-1
116 schema:name Cyclosporin
117 rdf:type schema:Book
118 Nabb982c3df5b46758d07efc44af3ffa7 schema:name Springer Nature - SN SciGraph project
119 rdf:type schema:Organization
120 Nec24c7db9cc641da8bbd5a31e4e55256 schema:location Dordrecht
121 schema:name Springer Netherlands
122 rdf:type schema:Organisation
123 Neca4a6d6a97d489096e88a95641629cf rdf:first sg:person.0674650317.92
124 rdf:rest Nf580247fc8a242ea86558a653f359ec4
125 Nedd984d13f1b4bb2b359aa5179891469 rdf:first N0161e3b68fee4f67acc89130a579578c
126 rdf:rest rdf:nil
127 Nf580247fc8a242ea86558a653f359ec4 rdf:first sg:person.070474653.50
128 rdf:rest rdf:nil
129 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
130 schema:name Medical and Health Sciences
131 rdf:type schema:DefinedTerm
132 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
133 schema:name Immunology
134 rdf:type schema:DefinedTerm
135 sg:person.0674650317.92 schema:familyName Motta
136 schema:givenName Iris
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674650317.92
138 rdf:type schema:Person
139 sg:person.070474653.50 schema:familyName Truffa-Bachi
140 schema:givenName Paolo
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.070474653.50
142 rdf:type schema:Person
143 sg:pub.10.1007/bf00915009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048497807
144 https://doi.org/10.1007/bf00915009
145 rdf:type schema:CreativeWork
146 sg:pub.10.1007/bf01973261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051012626
147 https://doi.org/10.1007/bf01973261
148 rdf:type schema:CreativeWork
149 sg:pub.10.1038/287542a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019146409
150 https://doi.org/10.1038/287542a0
151 rdf:type schema:CreativeWork
152 sg:pub.10.1038/289300a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015730683
153 https://doi.org/10.1038/289300a0
154 rdf:type schema:CreativeWork
155 sg:pub.10.1038/newbio237015a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011836543
156 https://doi.org/10.1038/newbio237015a0
157 rdf:type schema:CreativeWork
158 https://app.dimensions.ai/details/publication/pub.1074659988 schema:CreativeWork
159 https://app.dimensions.ai/details/publication/pub.1078801513 schema:CreativeWork
160 https://app.dimensions.ai/details/publication/pub.1078816691 schema:CreativeWork
161 https://app.dimensions.ai/details/publication/pub.1078821976 schema:CreativeWork
162 https://app.dimensions.ai/details/publication/pub.1079060168 schema:CreativeWork
163 https://app.dimensions.ai/details/publication/pub.1079466529 schema:CreativeWork
164 https://app.dimensions.ai/details/publication/pub.1079493304 schema:CreativeWork
165 https://app.dimensions.ai/details/publication/pub.1079501223 schema:CreativeWork
166 https://app.dimensions.ai/details/publication/pub.1079503499 schema:CreativeWork
167 https://app.dimensions.ai/details/publication/pub.1079508372 schema:CreativeWork
168 https://app.dimensions.ai/details/publication/pub.1079551536 schema:CreativeWork
169 https://app.dimensions.ai/details/publication/pub.1079555331 schema:CreativeWork
170 https://app.dimensions.ai/details/publication/pub.1079661323 schema:CreativeWork
171 https://app.dimensions.ai/details/publication/pub.1079778816 schema:CreativeWork
172 https://app.dimensions.ai/details/publication/pub.1079780797 schema:CreativeWork
173 https://app.dimensions.ai/details/publication/pub.1079796708 schema:CreativeWork
174 https://app.dimensions.ai/details/publication/pub.1079954327 schema:CreativeWork
175 https://app.dimensions.ai/details/publication/pub.1081595379 schema:CreativeWork
176 https://app.dimensions.ai/details/publication/pub.1081657839 schema:CreativeWork
177 https://app.dimensions.ai/details/publication/pub.1081671655 schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1081681407 schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1081684446 schema:CreativeWork
180 https://app.dimensions.ai/details/publication/pub.1081978855 schema:CreativeWork
181 https://app.dimensions.ai/details/publication/pub.1082077440 schema:CreativeWork
182 https://app.dimensions.ai/details/publication/pub.1082127306 schema:CreativeWork
183 https://doi.org/10.1002/eji.1830121013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010013338
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1002/eji.1830121207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050566375
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1002/eji.1830130503 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041243853
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1002/eji.1830140308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014513663
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1002/eji.1830140309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037843516
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1002/eji.1830170222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012594950
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1002/jlb.38.2.231 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080008436
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/0008-8749(84)90032-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039871900
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/0008-8749(85)90096-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051829561
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/0008-8749(86)90310-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036696523
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/0008-8749(87)90281-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050129738
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/0165-2478(86)90051-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053018297
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/0167-5699(82)90095-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004749611
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/0167-5699(85)90061-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032924641
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/0167-5699(86)90148-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051858058
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/0167-5699(88)91259-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025339056
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/0192-0561(84)90037-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002047449
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/s0092-8674(85)80080-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043529825
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/s0769-2617(87)80001-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040047009
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/s0769-2625(84)81188-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023189298
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/s0769-2625(85)80003-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046667458
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/s0769-2625(87)80135-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005479594
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1073/pnas.77.3.1612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000399504
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1073/pnas.83.2.437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028463371
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1073/pnas.83.8.2599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049434492
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1084/jem.148.6.1628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006102264
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1084/jem.150.6.1339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026171464
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1084/jem.155.5.1523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033456611
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1084/jem.156.6.1821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043120328
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1084/jem.157.2.530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043399270
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1084/jem.158.3.690 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042680401
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1084/jem.160.3.679 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019761424
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1097/00007890-197901000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025002301
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1111/j.1365-3083.1979.tb03278.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049417407
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1111/j.1365-3083.1983.tb00787.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037378189
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1111/j.1365-3083.1985.tb01864.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033807783
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1111/j.1600-065x.1980.tb00333.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034408147
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1111/j.1600-065x.1982.tb00421.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026387599
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1111/j.1600-065x.1982.tb00423.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030491752
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1111/j.1600-065x.1982.tb00425.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026623127
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1146/annurev.iy.01.040183.001235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011542964
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1146/annurev.iy.01.040183.001515 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049622973
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1146/annurev.iy.03.040185.002145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008257972
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1146/annurev.iy.05.040187.001135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050851818
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1146/annurev.iy.06.040188.002413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031117624
272 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...