Economic Fabrication and Utilisation of Agar Composites in Bioselective Recovery in Fixed and Fluidised Beds View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1990

AUTHORS

Nigel B. Gibson , Andrew Lyddiatt

ABSTRACT

The assembly and characterisation of beaded forms of agar (100-500 μm) formed in simple, economic emulsification procedures is described. Such particles have been chemically cross-linked to enhance physical, temperature and pH stabilities, and have been subsequently derivatised with ion-exchange groups, textile dyes and blood antigens to form selective adsorbents. Materials have been characterised in single-step, fixed bed concentrations and/or purifications of albumin from solution and monoclonal antibodies from animal cell culture broths. The introduction of inert, dense particles during bead emulsification has yielded material suited to similar product recoveries from biological suspensions in fluidised bed contactors. Direct comparison has been made with conventional commercial chromatographic materials in terms of performance efficiency and cost effectiveness in realistic biorecoveries. More... »

PAGES

152-161

References to SciGraph publications

  • 1987-12. Large-Scale Affinity Chromatography in NATURE BIOTECHNOLOGY
  • 1988-08. Macrosorb kieselguhr-agarose composite adsorbents in APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
  • Book

    TITLE

    Separations for Biotechnology 2

    ISBN

    978-94-010-6839-0
    978-94-009-0783-6

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-94-009-0783-6_17

    DOI

    http://dx.doi.org/10.1007/978-94-009-0783-6_17

    DIMENSIONS

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