Islet Isolation from Pancreatitis Pancreas for Islet Autotransplantation View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014-03-15

AUTHORS

A. N. Balamurugan , Gopalakrishnan Loganathan , Amber Lockridge , Sajjad M. Soltani , Gregory J. Beilman , Bernhard J. Hering , David E. R. Sutherland , Joshua J. Wilhelm

ABSTRACT

For patients suffering from intractable chronic pancreatitis, surgical removal of the pancreas may be recommended. While pancreatectomy has the potential to alleviate suffering and prolong life, the induction of iatrogenic diabetes, through the loss of insulin-producing islet cells, becomes an immediate threat to the postoperative patient. Since the procedure was first performed in 1977 at the University of Minnesota, autologous islet transplantation has become the best treatment option to restore a patient’s ability to endogenously regulate their blood sugar. Autologous islet isolation starts with a specific procurement and packaging of the pancreas, which is then transported to a specialized clean-room facility. The pancreas is distended with tissue dissociation enzymes that digest the extracellular matrix of the pancreas, freeing the embedded cells, which are combined into a single tube. If necessary, this tissue is purified by density gradient and the islets transferred to a transplant bag for intraportal infusion back into the patient. The most critical factor for a positive metabolic outcome from this procedure is the islet mass transplanted, making total isolation yield of particular concern. While the pancreas contains an abundance of islets, even the best isolation techniques capture only half of these. Furthermore, patient-donor characteristics and tissue conditions, like fibrosis and cell atrophy, can further diminish islet yields. Our goal at the University of Minnesota has been to research the underlying factors that influence islet yield and viability and to propose specific procedures designed to optimize isolation success regardless of tissue condition. The purpose of this review is to describe our basic protocol as well as to highlight our system of flexible techniques that can be adapted based on an ongoing evaluation of each individual pancreas and the procedural progress itself. More... »

PAGES

1-25

Book

TITLE

Islets of Langerhans, 2. ed.

ISBN

978-94-007-6884-0

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-94-007-6884-0_48-3

DOI

http://dx.doi.org/10.1007/978-94-007-6884-0_48-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043984119


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Balamurugan", 
        "givenName": "A. N.", 
        "id": "sg:person.013566567154.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013566567154.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Loganathan", 
        "givenName": "Gopalakrishnan", 
        "id": "sg:person.01372207601.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372207601.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lockridge", 
        "givenName": "Amber", 
        "id": "sg:person.01241427445.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241427445.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Soltani", 
        "givenName": "Sajjad M.", 
        "id": "sg:person.01031450541.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031450541.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beilman", 
        "givenName": "Gregory J.", 
        "id": "sg:person.012130265534.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012130265534.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hering", 
        "givenName": "Bernhard J.", 
        "id": "sg:person.016406322417.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016406322417.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sutherland", 
        "givenName": "David E. R.", 
        "id": "sg:person.0660363072.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660363072.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Schulze Diabetes Institute, University of Minnesota", 
          "id": "http://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Department of Surgery, Schulze Diabetes Institute, University of Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilhelm", 
        "givenName": "Joshua J.", 
        "id": "sg:person.014622173157.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014622173157.65"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2014-03-15", 
    "datePublishedReg": "2014-03-15", 
    "description": "For patients suffering from intractable chronic pancreatitis, surgical removal of the pancreas may be recommended. While pancreatectomy has the potential to alleviate suffering and prolong life, the induction of iatrogenic diabetes, through the loss of insulin-producing islet cells, becomes an immediate threat to the postoperative patient. Since the procedure was first performed in 1977 at the University of Minnesota, autologous islet transplantation has become the best treatment option to restore a patient\u2019s ability to endogenously regulate their blood sugar. Autologous islet isolation starts with a specific procurement and packaging of the pancreas, which is then transported to a specialized clean-room facility. The pancreas is distended with tissue dissociation enzymes that digest the extracellular matrix of the pancreas, freeing the embedded cells, which are combined into a single tube. If necessary, this tissue is purified by density gradient and the islets transferred to a transplant bag for intraportal infusion back into the patient. The most critical factor for a positive metabolic outcome from this procedure is the islet mass transplanted, making total isolation yield of particular concern. While the pancreas contains an abundance of islets, even the best isolation techniques capture only half of these. Furthermore, patient-donor characteristics and tissue conditions, like fibrosis and cell atrophy, can further diminish islet yields. Our goal at the University of Minnesota has been to research the underlying factors that influence islet yield and viability and to propose specific procedures designed to optimize isolation success regardless of tissue condition. The purpose of this review is to describe our basic protocol as well as to highlight our system of flexible techniques that can be adapted based on an ongoing evaluation of each individual pancreas and the procedural progress itself.", 
    "editor": [
      {
        "familyName": "Islam", 
        "givenName": "Md. Shahidul", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-94-007-6884-0_48-3", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-94-007-6884-0"
      ], 
      "name": "Islets of Langerhans, 2. ed.", 
      "type": "Book"
    }, 
    "keywords": [
      "islet yield", 
      "islet isolation", 
      "insulin-producing islet cells", 
      "intractable chronic pancreatitis", 
      "autologous islet transplantation", 
      "best treatment option", 
      "tissue conditions", 
      "positive metabolic outcomes", 
      "individual pancreas", 
      "islet autotransplantation", 
      "postoperative patients", 
      "chronic pancreatitis", 
      "blood sugar", 
      "intraportal infusion", 
      "surgical removal", 
      "islet transplantation", 
      "treatment options", 
      "metabolic outcomes", 
      "islet mass", 
      "cell atrophy", 
      "University of Minnesota", 
      "iatrogenic diabetes", 
      "patient's ability", 
      "prolong life", 
      "islet cells", 
      "pancreas", 
      "patients", 
      "better isolation techniques", 
      "isolation success", 
      "ongoing evaluation", 
      "islets", 
      "tissue dissociation", 
      "extracellular matrix", 
      "pancreatectomy", 
      "autotransplantation", 
      "pancreatitis", 
      "diabetes", 
      "cells", 
      "transplantation", 
      "atrophy", 
      "infusion", 
      "fibrosis", 
      "particular concern", 
      "basic protocol", 
      "outcomes", 
      "specific procedures", 
      "factors", 
      "procedure", 
      "tissue", 
      "induction", 
      "Minnesota", 
      "immediate threat", 
      "isolation yield", 
      "isolation techniques", 
      "review", 
      "options", 
      "suffering", 
      "isolation", 
      "ability", 
      "half", 
      "life", 
      "abundance", 
      "evaluation", 
      "critical factor", 
      "viability", 
      "protocol", 
      "loss", 
      "density gradient", 
      "single tube", 
      "purpose", 
      "mass", 
      "yield", 
      "concern", 
      "University", 
      "removal", 
      "sugars", 
      "conditions", 
      "success", 
      "tube", 
      "technique", 
      "facilities", 
      "potential", 
      "specific procurements", 
      "goal", 
      "bags", 
      "dissociation", 
      "characteristics", 
      "procurement", 
      "gradient", 
      "clean-room facilities", 
      "threat", 
      "packaging", 
      "system", 
      "matrix", 
      "flexible technique", 
      "Autologous islet isolation", 
      "specialized clean-room facility", 
      "transplant bag", 
      "total isolation yield", 
      "abundance of islets", 
      "patient-donor characteristics", 
      "Pancreatitis Pancreas"
    ], 
    "name": "Islet Isolation from Pancreatitis Pancreas for Islet Autotransplantation", 
    "pagination": "1-25", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1043984119"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-94-007-6884-0_48-3"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-94-007-6884-0_48-3", 
      "https://app.dimensions.ai/details/publication/pub.1043984119"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2021-12-01T20:06", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/chapter/chapter_350.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-94-007-6884-0_48-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-94-007-6884-0_48-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-94-007-6884-0_48-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-94-007-6884-0_48-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-94-007-6884-0_48-3'


 

This table displays all metadata directly associated to this object as RDF triples.

210 TRIPLES      23 PREDICATES      127 URIs      120 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-94-007-6884-0_48-3 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Nd6ce09a9e6704d9692c4717ce288a79b
4 schema:datePublished 2014-03-15
5 schema:datePublishedReg 2014-03-15
6 schema:description For patients suffering from intractable chronic pancreatitis, surgical removal of the pancreas may be recommended. While pancreatectomy has the potential to alleviate suffering and prolong life, the induction of iatrogenic diabetes, through the loss of insulin-producing islet cells, becomes an immediate threat to the postoperative patient. Since the procedure was first performed in 1977 at the University of Minnesota, autologous islet transplantation has become the best treatment option to restore a patient’s ability to endogenously regulate their blood sugar. Autologous islet isolation starts with a specific procurement and packaging of the pancreas, which is then transported to a specialized clean-room facility. The pancreas is distended with tissue dissociation enzymes that digest the extracellular matrix of the pancreas, freeing the embedded cells, which are combined into a single tube. If necessary, this tissue is purified by density gradient and the islets transferred to a transplant bag for intraportal infusion back into the patient. The most critical factor for a positive metabolic outcome from this procedure is the islet mass transplanted, making total isolation yield of particular concern. While the pancreas contains an abundance of islets, even the best isolation techniques capture only half of these. Furthermore, patient-donor characteristics and tissue conditions, like fibrosis and cell atrophy, can further diminish islet yields. Our goal at the University of Minnesota has been to research the underlying factors that influence islet yield and viability and to propose specific procedures designed to optimize isolation success regardless of tissue condition. The purpose of this review is to describe our basic protocol as well as to highlight our system of flexible techniques that can be adapted based on an ongoing evaluation of each individual pancreas and the procedural progress itself.
7 schema:editor Na65ec4bb726949559ce4f7ae7b23a393
8 schema:genre chapter
9 schema:inLanguage en
10 schema:isAccessibleForFree false
11 schema:isPartOf N672f76764eaf4994917f83ade7596383
12 schema:keywords Autologous islet isolation
13 Minnesota
14 Pancreatitis Pancreas
15 University
16 University of Minnesota
17 ability
18 abundance
19 abundance of islets
20 atrophy
21 autologous islet transplantation
22 autotransplantation
23 bags
24 basic protocol
25 best treatment option
26 better isolation techniques
27 blood sugar
28 cell atrophy
29 cells
30 characteristics
31 chronic pancreatitis
32 clean-room facilities
33 concern
34 conditions
35 critical factor
36 density gradient
37 diabetes
38 dissociation
39 evaluation
40 extracellular matrix
41 facilities
42 factors
43 fibrosis
44 flexible technique
45 goal
46 gradient
47 half
48 iatrogenic diabetes
49 immediate threat
50 individual pancreas
51 induction
52 infusion
53 insulin-producing islet cells
54 intractable chronic pancreatitis
55 intraportal infusion
56 islet autotransplantation
57 islet cells
58 islet isolation
59 islet mass
60 islet transplantation
61 islet yield
62 islets
63 isolation
64 isolation success
65 isolation techniques
66 isolation yield
67 life
68 loss
69 mass
70 matrix
71 metabolic outcomes
72 ongoing evaluation
73 options
74 outcomes
75 packaging
76 pancreas
77 pancreatectomy
78 pancreatitis
79 particular concern
80 patient's ability
81 patient-donor characteristics
82 patients
83 positive metabolic outcomes
84 postoperative patients
85 potential
86 procedure
87 procurement
88 prolong life
89 protocol
90 purpose
91 removal
92 review
93 single tube
94 specialized clean-room facility
95 specific procedures
96 specific procurements
97 success
98 suffering
99 sugars
100 surgical removal
101 system
102 technique
103 threat
104 tissue
105 tissue conditions
106 tissue dissociation
107 total isolation yield
108 transplant bag
109 transplantation
110 treatment options
111 tube
112 viability
113 yield
114 schema:name Islet Isolation from Pancreatitis Pancreas for Islet Autotransplantation
115 schema:pagination 1-25
116 schema:productId N65f5d56bab7a49afa94a9368d4b75f78
117 Na1fde8c694fc4cb7b1f52dc1de53a2e1
118 schema:publisher N05f05c20155e47d996b19e64b9d1ae67
119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043984119
120 https://doi.org/10.1007/978-94-007-6884-0_48-3
121 schema:sdDatePublished 2021-12-01T20:06
122 schema:sdLicense https://scigraph.springernature.com/explorer/license/
123 schema:sdPublisher Ne9ec1fe604174192b491f1a46380e1ca
124 schema:url https://doi.org/10.1007/978-94-007-6884-0_48-3
125 sgo:license sg:explorer/license/
126 sgo:sdDataset chapters
127 rdf:type schema:Chapter
128 N042c48b6ed904339a9c4108de38e3247 rdf:first sg:person.012130265534.18
129 rdf:rest N26da9c00e189496a9f0400a9f182cde8
130 N05f05c20155e47d996b19e64b9d1ae67 schema:name Springer Nature
131 rdf:type schema:Organisation
132 N26da9c00e189496a9f0400a9f182cde8 rdf:first sg:person.016406322417.09
133 rdf:rest Na2494192903f486aba6bfbcc143112bb
134 N2dfe72db5b4241f5abfb91b1b115c542 rdf:first sg:person.01241427445.35
135 rdf:rest Ne084934d787f495fa78684353eb9f1e7
136 N351882973645453c839be21b2a60fd00 schema:familyName Islam
137 schema:givenName Md. Shahidul
138 rdf:type schema:Person
139 N65f5d56bab7a49afa94a9368d4b75f78 schema:name dimensions_id
140 schema:value pub.1043984119
141 rdf:type schema:PropertyValue
142 N672f76764eaf4994917f83ade7596383 schema:isbn 978-94-007-6884-0
143 schema:name Islets of Langerhans, 2. ed.
144 rdf:type schema:Book
145 Na1fde8c694fc4cb7b1f52dc1de53a2e1 schema:name doi
146 schema:value 10.1007/978-94-007-6884-0_48-3
147 rdf:type schema:PropertyValue
148 Na2494192903f486aba6bfbcc143112bb rdf:first sg:person.0660363072.84
149 rdf:rest Ne60cc512dacd4d1a8dcdc00cde262365
150 Na65ec4bb726949559ce4f7ae7b23a393 rdf:first N351882973645453c839be21b2a60fd00
151 rdf:rest rdf:nil
152 Nd6ce09a9e6704d9692c4717ce288a79b rdf:first sg:person.013566567154.60
153 rdf:rest Nea618c5fb5904097a1091770fc41564c
154 Ne084934d787f495fa78684353eb9f1e7 rdf:first sg:person.01031450541.12
155 rdf:rest N042c48b6ed904339a9c4108de38e3247
156 Ne60cc512dacd4d1a8dcdc00cde262365 rdf:first sg:person.014622173157.65
157 rdf:rest rdf:nil
158 Ne9ec1fe604174192b491f1a46380e1ca schema:name Springer Nature - SN SciGraph project
159 rdf:type schema:Organization
160 Nea618c5fb5904097a1091770fc41564c rdf:first sg:person.01372207601.89
161 rdf:rest N2dfe72db5b4241f5abfb91b1b115c542
162 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
163 schema:name Medical and Health Sciences
164 rdf:type schema:DefinedTerm
165 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
166 schema:name Clinical Sciences
167 rdf:type schema:DefinedTerm
168 sg:person.01031450541.12 schema:affiliation grid-institutes:grid.17635.36
169 schema:familyName Soltani
170 schema:givenName Sajjad M.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031450541.12
172 rdf:type schema:Person
173 sg:person.012130265534.18 schema:affiliation grid-institutes:grid.17635.36
174 schema:familyName Beilman
175 schema:givenName Gregory J.
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012130265534.18
177 rdf:type schema:Person
178 sg:person.01241427445.35 schema:affiliation grid-institutes:grid.17635.36
179 schema:familyName Lockridge
180 schema:givenName Amber
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241427445.35
182 rdf:type schema:Person
183 sg:person.013566567154.60 schema:affiliation grid-institutes:grid.17635.36
184 schema:familyName Balamurugan
185 schema:givenName A. N.
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013566567154.60
187 rdf:type schema:Person
188 sg:person.01372207601.89 schema:affiliation grid-institutes:grid.17635.36
189 schema:familyName Loganathan
190 schema:givenName Gopalakrishnan
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372207601.89
192 rdf:type schema:Person
193 sg:person.014622173157.65 schema:affiliation grid-institutes:grid.17635.36
194 schema:familyName Wilhelm
195 schema:givenName Joshua J.
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014622173157.65
197 rdf:type schema:Person
198 sg:person.016406322417.09 schema:affiliation grid-institutes:grid.17635.36
199 schema:familyName Hering
200 schema:givenName Bernhard J.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016406322417.09
202 rdf:type schema:Person
203 sg:person.0660363072.84 schema:affiliation grid-institutes:grid.17635.36
204 schema:familyName Sutherland
205 schema:givenName David E. R.
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660363072.84
207 rdf:type schema:Person
208 grid-institutes:grid.17635.36 schema:alternateName Department of Surgery, Schulze Diabetes Institute, University of Minnesota
209 schema:name Department of Surgery, Schulze Diabetes Institute, University of Minnesota
210 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...