Organ-Specific Autoimmunity in HCV-Positive Patients View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Corrado Betterle , Fabio Presotto

ABSTRACT

Chronic hepatitis C virus (HCV) infection predisposes patients to the onset of diseases involving other organ systems. Indeed, more than 50% of patients with HCV infection develop at least one autoimmune extrahepatic manifestation. These manifestations may be triggered by virus-induced autoimmunity with autoantibody production, autoreactive T cells, and intricate autoimmune reactions that lead to organ-specific or non-organ-specific autoimmune diseases involving the kidneys, skin, eyes, joints, nervous system, etc. Some extrahepatic manifestations of hepatitis C are relatively common (e.g., cryoglobulinemia), while others, such as autoimmune thyroid diseases or type 1 diabetes mellitus, are uncommon and their association with HCV has yet to be fully elucidated. In this chapter, we consider the main organ-specific autoimmune disorders directly related to HCV infection or indirectly induced by treatment for HCV infection, and interferons in particular. More... »

PAGES

43-51

Book

TITLE

HCV Infection and Cryoglobulinemia

ISBN

978-88-470-1704-7
978-88-470-1705-4

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-88-470-1705-4_5

DOI

http://dx.doi.org/10.1007/978-88-470-1705-4_5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047973497


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