Melatonin in Parkinson’s Disease and Its Therapeutic Potential View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

Venkataramanujam Srinivasan , U. S. Srinivasan , Charanjit Kaur , Rahimah Zakaria , Zahiruddin Othman , Edward C. Lauterbach , Dario Acuña-Castroviejo

ABSTRACT

Although the etiology of Parkinson’s disease (PD) is not known, most patients with PD experience sleep-related problems like difficulty in initiating and maintaining sleep, excessive daytime sleepiness, sleep fragmentation, and reductions in non-REM or REM sleep. Since melatonin and its analogues have sleep-promoting and sleep-wake rhythm-regulating actions, interest has been focused on the role of melatonin in PD. Interestingly use of melatonin in animal models of PD has shown that melatonin has been useful in improving the neurotoxic effects of administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), rotenone, or maneb and paraquat. Being an antioxidant melatonin counteracted the MPTP-induced lipid per oxidation. The finding of reduced expression of MT1 and MT2 melatonin receptors in amygdale and substantia nigra of patients with PD supports the involvement of melatonergic system in the possible etiology of PD. Use of melatonin or its analogues may be beneficial in treating patients with PD for improving the sleep quality and also for enhancing the neuroprotection against oxidative stress seen in PD. More... »

PAGES

249-261

References to SciGraph publications

  • 2008-04. Melatonin, environmental light, and breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2005-07. Functional MT1 and MT2 melatonin receptors in mammals in ENDOCRINE
  • 2004-03. Initiation of Neuronal Damage by Complex I Deficiency and Oxidative Stress in Parkinson's Disease in NEUROCHEMICAL RESEARCH
  • 2009-06. Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction in ACTA NEUROPATHOLOGICA
  • 2003-06. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria in MOLECULAR NEUROBIOLOGY
  • 2008-02. Is REM sleep Behaviour Disorder (RBD) a risk factor of dementia in idiopathic Parkinson's disease? in JOURNAL OF NEUROLOGY
  • 2005-12. Melatonin, immune function and aging in IMMUNITY & AGEING
  • 1999-12. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease in NATURE MEDICINE
  • 2005-12. Role of melatonin in neurodegenerative diseases in NEUROTOXICITY RESEARCH
  • 2007-04. Effect of exogenous melatonin on sleep and motor dysfunction in Parkinson's disease in JOURNAL OF NEUROLOGY
  • 2007-04. Parkinson’s disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons in ACTA NEUROPATHOLOGICA
  • 2004-08. MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease in JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
  • 2003-10. Mitochondrial Dysfunction and Reactive Oxygen Species in Excitotoxicity and Apoptosis: Implications for the Pathogenesis of Neurodegenerative Diseases in NEUROCHEMICAL RESEARCH
  • Book

    TITLE

    Melatonin and Melatonergic Drugs in Clinical Practice

    ISBN

    978-81-322-0824-2
    978-81-322-0825-9

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-81-322-0825-9_17

    DOI

    http://dx.doi.org/10.1007/978-81-322-0825-9_17

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1040159012


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Cardiorespiratory Medicine and Haematology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "name": [
                "Sri Sathya Sai Medical Educational and Research Foundation, An International Medical Sciences Research Study Center, Prasanthi Nilayam, 40-Kovai Thirunagar Extn, Goldwins, Coimbatore, TN, 641014, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Srinivasan", 
            "givenName": "Venkataramanujam", 
            "id": "sg:person.01237721775.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237721775.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Fortis Malar Hospital", 
              "id": "https://www.grid.ac/institutes/grid.460829.1", 
              "name": [
                "Department of Neurosurgery, Fortis Malar Hospital, Gandhi Nagar Main Road, Adyar, Chennai, TN, 600020, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Srinivasan", 
            "givenName": "U. S.", 
            "id": "sg:person.0604043132.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604043132.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National University of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.4280.e", 
              "name": [
                "Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, BLK MD 10, 4 Medical Drive, Singapore, 117597, Singapore"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kaur", 
            "givenName": "Charanjit", 
            "id": "sg:person.01174461275.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174461275.76"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Universiti Sains Malaysia", 
              "id": "https://www.grid.ac/institutes/grid.11875.3a", 
              "name": [
                "Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 16150, Malaysia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zakaria", 
            "givenName": "Rahimah", 
            "id": "sg:person.01224603156.65", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224603156.65"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hospital Universiti Sains Malaysia", 
              "id": "https://www.grid.ac/institutes/grid.428821.5", 
              "name": [
                "Department of Psychiatry, School of Medical Sciences, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, 16150, Malaysia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Othman", 
            "givenName": "Zahiruddin", 
            "id": "sg:person.01341031556.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341031556.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Mercer University", 
              "id": "https://www.grid.ac/institutes/grid.259906.1", 
              "name": [
                "Department of Psychiatry and Behavioral Sciences and the Department of Internal Medicine, Neurology Section, Mercer University School of Medicine, 655 First Street, Macon, GA\u00a031201, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lauterbach", 
            "givenName": "Edward C.", 
            "id": "sg:person.0632502703.19", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632502703.19"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Physiology, Centro de Investigaci\u00f3n Biom\u00e9dica, Parque de Ciencias de la Salud, Avda. del Conocimiento s/n, Armilla, Granada, 18100, Spain"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Acu\u00f1a-Castroviejo", 
            "givenName": "Dario", 
            "id": "sg:person.0610157125.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610157125.40"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1182/blood-2003-03-0779", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000085349"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-009-0538-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000508964", 
              "https://doi.org/10.1007/s00401-009-0538-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-009-0538-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000508964", 
              "https://doi.org/10.1007/s00401-009-0538-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-009-0538-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000508964", 
              "https://doi.org/10.1007/s00401-009-0538-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1471-4159.1989.tb09133.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000702028"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2147/ndt.s4578", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000788272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainres.2005.04.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000858007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainres.2005.04.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000858007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.sleep.2004.07.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001437775"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1531-8257(200007)15:4<669::aid-mds1011>3.0.co;2-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001957187"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainresbull.2009.12.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002072864"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-8993(95)96872-i", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003490623"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuint.2005.12.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003975223"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.parkreldis.2003.11.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004893527"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/123.2.331", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005311422"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0031-9384(99)00023-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006921373"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainres.2005.05.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006963030"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainres.2005.05.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006963030"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m005141200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007184475"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0896-6273(94)90055-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007737076"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/23.3.327", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008722740"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10549-007-9617-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008876587", 
              "https://doi.org/10.1007/s10549-007-9617-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/jgp.0b013e3181e448f7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009083847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awp263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009697029"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awp263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009697029"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2010.00819.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009754331"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2010.00819.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009754331"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0891988704267465", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010065397"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0891988704267465", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010065397"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1385/endo:27:2:101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010104011", 
              "https://doi.org/10.1385/endo:27:2:101"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/mds.10425", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011012863"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.psc.2004.07.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011812038"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1432-1033.2003.03430.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012287438"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.00-0129com", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012463277"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0896-6273(00)80350-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014431501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0278-5846(89)90052-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014508056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0278-5846(89)90052-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014508056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.brainres.2005.09.041", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015162168"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuropharm.2004.09.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015323986"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000542-200610000-00029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015335369"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000542-200610000-00029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015335369"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00001756-199812210-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015705916"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00001756-199812210-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015705916"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/mds.10167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016472005"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0197-4580(02)00065-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016528708"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0197-4580(02)00065-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016528708"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00002826-200207000-00002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016612946"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1385/mn:27:3:325", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017950416", 
              "https://doi.org/10.1385/mn:27:3:325"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clineuro.2010.02.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018043686"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-007-0193-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018593035", 
              "https://doi.org/10.1007/s00401-007-0193-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1742-4658.2008.06302.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018716415"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(95)92509-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018935078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(95)92509-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018935078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.1997.tb00342.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018959243"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.pharmthera.2005.05.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019297141"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.pharmthera.2005.05.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019297141"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.sleep.2003.10.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019767897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.smrv.2004.05.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021691158"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1468-1331.2009.02848.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021713266"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0024-3205(96)00606-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021754734"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1534735408322846", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024061881"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1534735408322846", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024061881"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molbrainres.2005.01.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024496041"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbabio.2004.03.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024589442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0197-4580(02)00133-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025321879"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0197-4580(02)00133-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025321879"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neulet.2008.04.099", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026400208"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.sleep.2005.04.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026795733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.sleep.2005.04.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026795733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1034/j.1600-079x.2002.00841.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026911239"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/09513590903159649", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028969499"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-8993(02)02551-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029611554"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gks630", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029712603"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/07420520701420717", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029868898"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jnr.22123", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030598008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jnr.22123", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030598008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2006.00412.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030904485"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/70978", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031949261", 
              "https://doi.org/10.1038/70978"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ana.410320616", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032351171"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/b:jobb.0000041771.66775.d5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032430633", 
              "https://doi.org/10.1023/b:jobb.0000041771.66775.d5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1742-4933-2-17", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033294837", 
              "https://doi.org/10.1186/1742-4933-2-17"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1749-6632.1985.tb11825.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033809071"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00415-006-0390-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035100308", 
              "https://doi.org/10.1007/s00415-006-0390-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00415-006-0390-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035100308", 
              "https://doi.org/10.1007/s00415-006-0390-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1432206", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035678621"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3181ebdd79", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036067209"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.0b013e3181ebdd79", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036067209"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2007.01.063", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036675623"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/smrv.2002.0229", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038357272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/smrv.2002.0229", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038357272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1515/revneuro.2008.19.4-5.245", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039049444"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s1092852900017260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039906993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/07420520701672556", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040978198"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/mds.10429", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042332707"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awm097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042667052"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1025682611389", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043134078", 
              "https://doi.org/10.1023/a:1025682611389"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1353-8020(99)00011-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043332117"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00002826-198812000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044203673"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2005.00282.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044515150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2005.00282.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044515150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/b:nere.0000014827.94562.4b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044554912", 
              "https://doi.org/10.1023/b:nere.0000014827.94562.4b"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1531-8257(199911)14:6<922::aid-mds1003>3.0.co;2-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045836851"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000148191", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046546461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.92.19.8734", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046904595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0891-5849(91)90009-r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048468249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0891-5849(91)90009-r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048468249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/brain/awm056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049085482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/emboj/20.15.3967", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049155093"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ana.410320703", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049607259"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archneurol.2010.135", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049943065"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/nbdi.2000.0319", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050210436"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00415-008-0629-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050412882", 
              "https://doi.org/10.1007/s00415-008-0629-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00415-008-0629-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050412882", 
              "https://doi.org/10.1007/s00415-008-0629-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2009.00713.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050553140"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1600-079x.2009.00713.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050553140"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1113/jphysiol.2004.073742", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051713165"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf03033887", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051841365", 
              "https://doi.org/10.1007/bf03033887"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf03033887", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051841365", 
              "https://doi.org/10.1007/bf03033887"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0047-6374(01)00384-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051854029"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1600-079x.2003.00096.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053658959"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jm050740o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055949781"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jm050740o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055949781"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/jnp.2010.22.1.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063512791"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/jnp.2010.22.2.130", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063512795"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/edrv-1-2-109", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064237851"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000179346.39655.e0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064347486"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000179346.39655.e0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064347486"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000179346.39655.e0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064347486"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000278114.14096.74", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064349648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000278114.14096.74", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064349648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000278114.14096.74", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064349648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.46.2.388", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373688"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.46.2.388", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373688"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.46.2.388", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373688"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.46.2.388", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064373688"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.58.7.1019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064380729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.58.7.1019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064380729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.58.7.1019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064380729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1568026023394335", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069192858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1568026023394407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069192862"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/187152712800269740", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069221718"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075238442", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077115998", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078042032", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078148550", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079238655", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2014", 
        "datePublishedReg": "2014-01-01", 
        "description": "Although the etiology of Parkinson\u2019s disease (PD) is not known, most patients with PD experience sleep-related problems like difficulty in initiating and maintaining sleep, excessive daytime sleepiness, sleep fragmentation, and reductions in non-REM or REM sleep. Since melatonin and its analogues have sleep-promoting and sleep-wake rhythm-regulating actions, interest has been focused on the role of melatonin in PD. Interestingly use of melatonin in animal models of PD has shown that melatonin has been useful in improving the neurotoxic effects of administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), rotenone, or maneb and paraquat. Being an antioxidant melatonin counteracted the MPTP-induced lipid per oxidation. The finding of reduced expression of MT1 and MT2 melatonin receptors in amygdale and substantia nigra of patients with PD supports the involvement of melatonergic system in the possible etiology of PD. Use of melatonin or its analogues may be beneficial in treating patients with PD for improving the sleep quality and also for enhancing the neuroprotection against oxidative stress seen in PD.", 
        "editor": [
          {
            "familyName": "Srinivasan", 
            "givenName": "V.", 
            "type": "Person"
          }, 
          {
            "familyName": "Brzezinski", 
            "givenName": "Amnon", 
            "type": "Person"
          }, 
          {
            "familyName": "Oter", 
            "givenName": "Sukru", 
            "type": "Person"
          }, 
          {
            "familyName": "Shillcutt", 
            "givenName": "Samuel D.", 
            "type": "Person"
          }
        ], 
        "genre": "chapter", 
        "id": "sg:pub.10.1007/978-81-322-0825-9_17", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": {
          "isbn": [
            "978-81-322-0824-2", 
            "978-81-322-0825-9"
          ], 
          "name": "Melatonin and Melatonergic Drugs in Clinical Practice", 
          "type": "Book"
        }, 
        "name": "Melatonin in Parkinson\u2019s Disease and Its Therapeutic Potential", 
        "pagination": "249-261", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/978-81-322-0825-9_17"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "bf4da7be9c02e5e7619ca2741587d5d28bef0107bf1d8c504eb2b9406e99bfd5"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1040159012"
            ]
          }
        ], 
        "publisher": {
          "location": "New Delhi", 
          "name": "Springer India", 
          "type": "Organisation"
        }, 
        "sameAs": [
          "https://doi.org/10.1007/978-81-322-0825-9_17", 
          "https://app.dimensions.ai/details/publication/pub.1040159012"
        ], 
        "sdDataset": "chapters", 
        "sdDatePublished": "2019-04-15T10:21", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000069.jsonl", 
        "type": "Chapter", 
        "url": "http://link.springer.com/10.1007/978-81-322-0825-9_17"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-81-322-0825-9_17'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-81-322-0825-9_17'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-81-322-0825-9_17'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-81-322-0825-9_17'


     

    This table displays all metadata directly associated to this object as RDF triples.

    479 TRIPLES      23 PREDICATES      138 URIs      20 LITERALS      8 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/978-81-322-0825-9_17 schema:about anzsrc-for:11
    2 anzsrc-for:1102
    3 schema:author Nfcdcc4fd5b7947a9b6895f0285137d53
    4 schema:citation sg:pub.10.1007/bf03033887
    5 sg:pub.10.1007/s00401-007-0193-x
    6 sg:pub.10.1007/s00401-009-0538-8
    7 sg:pub.10.1007/s00415-006-0390-x
    8 sg:pub.10.1007/s00415-008-0629-9
    9 sg:pub.10.1007/s10549-007-9617-5
    10 sg:pub.10.1023/a:1025682611389
    11 sg:pub.10.1023/b:jobb.0000041771.66775.d5
    12 sg:pub.10.1023/b:nere.0000014827.94562.4b
    13 sg:pub.10.1038/70978
    14 sg:pub.10.1186/1742-4933-2-17
    15 sg:pub.10.1385/endo:27:2:101
    16 sg:pub.10.1385/mn:27:3:325
    17 https://app.dimensions.ai/details/publication/pub.1075238442
    18 https://app.dimensions.ai/details/publication/pub.1077115998
    19 https://app.dimensions.ai/details/publication/pub.1078042032
    20 https://app.dimensions.ai/details/publication/pub.1078148550
    21 https://app.dimensions.ai/details/publication/pub.1079238655
    22 https://doi.org/10.1001/archneurol.2010.135
    23 https://doi.org/10.1002/1531-8257(199911)14:6<922::aid-mds1003>3.0.co;2-7
    24 https://doi.org/10.1002/1531-8257(200007)15:4<669::aid-mds1011>3.0.co;2-5
    25 https://doi.org/10.1002/ana.410320616
    26 https://doi.org/10.1002/ana.410320703
    27 https://doi.org/10.1002/jnr.22123
    28 https://doi.org/10.1002/mds.10167
    29 https://doi.org/10.1002/mds.10425
    30 https://doi.org/10.1002/mds.10429
    31 https://doi.org/10.1006/nbdi.2000.0319
    32 https://doi.org/10.1016/0006-8993(95)96872-i
    33 https://doi.org/10.1016/0278-5846(89)90052-3
    34 https://doi.org/10.1016/0891-5849(91)90009-r
    35 https://doi.org/10.1016/0896-6273(94)90055-8
    36 https://doi.org/10.1016/j.bbabio.2004.03.016
    37 https://doi.org/10.1016/j.bbrc.2007.01.063
    38 https://doi.org/10.1016/j.brainres.2005.04.051
    39 https://doi.org/10.1016/j.brainres.2005.05.051
    40 https://doi.org/10.1016/j.brainres.2005.09.041
    41 https://doi.org/10.1016/j.brainresbull.2009.12.001
    42 https://doi.org/10.1016/j.clineuro.2010.02.011
    43 https://doi.org/10.1016/j.molbrainres.2005.01.002
    44 https://doi.org/10.1016/j.neuint.2005.12.016
    45 https://doi.org/10.1016/j.neulet.2008.04.099
    46 https://doi.org/10.1016/j.neuropharm.2004.09.007
    47 https://doi.org/10.1016/j.parkreldis.2003.11.006
    48 https://doi.org/10.1016/j.pharmthera.2005.05.007
    49 https://doi.org/10.1016/j.psc.2004.07.001
    50 https://doi.org/10.1016/j.sleep.2003.10.012
    51 https://doi.org/10.1016/j.sleep.2004.07.009
    52 https://doi.org/10.1016/j.sleep.2005.04.004
    53 https://doi.org/10.1016/j.smrv.2004.05.002
    54 https://doi.org/10.1016/s0006-8993(02)02551-9
    55 https://doi.org/10.1016/s0024-3205(96)00606-6
    56 https://doi.org/10.1016/s0031-9384(99)00023-2
    57 https://doi.org/10.1016/s0047-6374(01)00384-0
    58 https://doi.org/10.1016/s0140-6736(95)92509-0
    59 https://doi.org/10.1016/s0197-4580(02)00065-9
    60 https://doi.org/10.1016/s0197-4580(02)00133-1
    61 https://doi.org/10.1016/s0896-6273(00)80350-5
    62 https://doi.org/10.1016/s1353-8020(99)00011-5
    63 https://doi.org/10.1017/s1092852900017260
    64 https://doi.org/10.1021/jm050740o
    65 https://doi.org/10.1034/j.1600-079x.2002.00841.x
    66 https://doi.org/10.1046/j.1432-1033.2003.03430.x
    67 https://doi.org/10.1046/j.1600-079x.2003.00096.x
    68 https://doi.org/10.1053/smrv.2002.0229
    69 https://doi.org/10.1073/pnas.92.19.8734
    70 https://doi.org/10.1074/jbc.m005141200
    71 https://doi.org/10.1080/07420520701420717
    72 https://doi.org/10.1080/07420520701672556
    73 https://doi.org/10.1093/brain/123.2.331
    74 https://doi.org/10.1093/brain/awm056
    75 https://doi.org/10.1093/brain/awm097
    76 https://doi.org/10.1093/brain/awp263
    77 https://doi.org/10.1093/emboj/20.15.3967
    78 https://doi.org/10.1093/nar/23.3.327
    79 https://doi.org/10.1093/nar/gks630
    80 https://doi.org/10.1096/fj.00-0129com
    81 https://doi.org/10.1097/00000542-200610000-00029
    82 https://doi.org/10.1097/00001756-199812210-00011
    83 https://doi.org/10.1097/00002826-198812000-00004
    84 https://doi.org/10.1097/00002826-200207000-00002
    85 https://doi.org/10.1097/jgp.0b013e3181e448f7
    86 https://doi.org/10.1101/gad.1432206
    87 https://doi.org/10.1111/j.1468-1331.2009.02848.x
    88 https://doi.org/10.1111/j.1471-4159.1989.tb09133.x
    89 https://doi.org/10.1111/j.1600-079x.1997.tb00342.x
    90 https://doi.org/10.1111/j.1600-079x.2005.00282.x
    91 https://doi.org/10.1111/j.1600-079x.2006.00412.x
    92 https://doi.org/10.1111/j.1600-079x.2009.00713.x
    93 https://doi.org/10.1111/j.1600-079x.2010.00819.x
    94 https://doi.org/10.1111/j.1742-4658.2008.06302.x
    95 https://doi.org/10.1111/j.1749-6632.1985.tb11825.x
    96 https://doi.org/10.1113/jphysiol.2004.073742
    97 https://doi.org/10.1159/000148191
    98 https://doi.org/10.1176/jnp.2010.22.1.8
    99 https://doi.org/10.1176/jnp.2010.22.2.130
    100 https://doi.org/10.1177/0891988704267465
    101 https://doi.org/10.1177/1534735408322846
    102 https://doi.org/10.1182/blood-2003-03-0779
    103 https://doi.org/10.1210/edrv-1-2-109
    104 https://doi.org/10.1212/01.wnl.0000179346.39655.e0
    105 https://doi.org/10.1212/01.wnl.0000278114.14096.74
    106 https://doi.org/10.1212/wnl.0b013e3181ebdd79
    107 https://doi.org/10.1212/wnl.46.2.388
    108 https://doi.org/10.1212/wnl.58.7.1019
    109 https://doi.org/10.1515/revneuro.2008.19.4-5.245
    110 https://doi.org/10.2147/ndt.s4578
    111 https://doi.org/10.2174/1568026023394335
    112 https://doi.org/10.2174/1568026023394407
    113 https://doi.org/10.2174/187152712800269740
    114 https://doi.org/10.3109/09513590903159649
    115 schema:datePublished 2014
    116 schema:datePublishedReg 2014-01-01
    117 schema:description Although the etiology of Parkinson’s disease (PD) is not known, most patients with PD experience sleep-related problems like difficulty in initiating and maintaining sleep, excessive daytime sleepiness, sleep fragmentation, and reductions in non-REM or REM sleep. Since melatonin and its analogues have sleep-promoting and sleep-wake rhythm-regulating actions, interest has been focused on the role of melatonin in PD. Interestingly use of melatonin in animal models of PD has shown that melatonin has been useful in improving the neurotoxic effects of administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), rotenone, or maneb and paraquat. Being an antioxidant melatonin counteracted the MPTP-induced lipid per oxidation. The finding of reduced expression of MT1 and MT2 melatonin receptors in amygdale and substantia nigra of patients with PD supports the involvement of melatonergic system in the possible etiology of PD. Use of melatonin or its analogues may be beneficial in treating patients with PD for improving the sleep quality and also for enhancing the neuroprotection against oxidative stress seen in PD.
    118 schema:editor N3a9513155e8b459a9b2d9cc4fa6aab67
    119 schema:genre chapter
    120 schema:inLanguage en
    121 schema:isAccessibleForFree false
    122 schema:isPartOf N6f6c9497419e4aeba3b21c5511e21f19
    123 schema:name Melatonin in Parkinson’s Disease and Its Therapeutic Potential
    124 schema:pagination 249-261
    125 schema:productId N5f09b232f7c44c7aa311784b671e74ca
    126 N96b3ed1bfce249a582c132e154d7848a
    127 Nda7a6752c4364ee2b487d6a0863ea139
    128 schema:publisher N2e044a8e26804a99aef88736109f5bf5
    129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040159012
    130 https://doi.org/10.1007/978-81-322-0825-9_17
    131 schema:sdDatePublished 2019-04-15T10:21
    132 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    133 schema:sdPublisher Nafdaac3516e640038c59899069614a77
    134 schema:url http://link.springer.com/10.1007/978-81-322-0825-9_17
    135 sgo:license sg:explorer/license/
    136 sgo:sdDataset chapters
    137 rdf:type schema:Chapter
    138 N0d398525f83345c189e9e5a2cd3e6cb6 rdf:first sg:person.0632502703.19
    139 rdf:rest Nd9d1f750d17443ba84b60b40a21fc2cd
    140 N0e0f4a9532194a50850dc642a9f92c9a rdf:first N4d69715df5b9486e9d1761516692738b
    141 rdf:rest rdf:nil
    142 N2e044a8e26804a99aef88736109f5bf5 schema:location New Delhi
    143 schema:name Springer India
    144 rdf:type schema:Organisation
    145 N376da5fa8b9c466f94745698dac0ff9b schema:familyName Oter
    146 schema:givenName Sukru
    147 rdf:type schema:Person
    148 N3a9513155e8b459a9b2d9cc4fa6aab67 rdf:first Nef7d397f30244d6e947b7f75fdd00e0e
    149 rdf:rest Ne0b3aad79c5d4249a3f98f25637ff014
    150 N4d69715df5b9486e9d1761516692738b schema:familyName Shillcutt
    151 schema:givenName Samuel D.
    152 rdf:type schema:Person
    153 N5f09b232f7c44c7aa311784b671e74ca schema:name dimensions_id
    154 schema:value pub.1040159012
    155 rdf:type schema:PropertyValue
    156 N60c5a23bdcb742849fc5e1d4fa221d38 rdf:first N376da5fa8b9c466f94745698dac0ff9b
    157 rdf:rest N0e0f4a9532194a50850dc642a9f92c9a
    158 N6f6c9497419e4aeba3b21c5511e21f19 schema:isbn 978-81-322-0824-2
    159 978-81-322-0825-9
    160 schema:name Melatonin and Melatonergic Drugs in Clinical Practice
    161 rdf:type schema:Book
    162 N71d0f933d1894fe7bdc5a9d8ef928421 schema:name Department of Physiology, Centro de Investigación Biomédica, Parque de Ciencias de la Salud, Avda. del Conocimiento s/n, Armilla, Granada, 18100, Spain
    163 rdf:type schema:Organization
    164 N844caf43772645d29ddd58509be7cd92 rdf:first sg:person.0604043132.25
    165 rdf:rest Nce2511fd7f8147b2b8cca7e044bad944
    166 N8492f691b3384d2ea8d23af7646cf838 rdf:first sg:person.01341031556.31
    167 rdf:rest N0d398525f83345c189e9e5a2cd3e6cb6
    168 N8bd1cf1d4a3e42b58c9e8aabea2425f2 schema:name Sri Sathya Sai Medical Educational and Research Foundation, An International Medical Sciences Research Study Center, Prasanthi Nilayam, 40-Kovai Thirunagar Extn, Goldwins, Coimbatore, TN, 641014, India
    169 rdf:type schema:Organization
    170 N96b3ed1bfce249a582c132e154d7848a schema:name doi
    171 schema:value 10.1007/978-81-322-0825-9_17
    172 rdf:type schema:PropertyValue
    173 Nafdaac3516e640038c59899069614a77 schema:name Springer Nature - SN SciGraph project
    174 rdf:type schema:Organization
    175 Nce2511fd7f8147b2b8cca7e044bad944 rdf:first sg:person.01174461275.76
    176 rdf:rest Nddef86f435654768ab0e3924d1caef4b
    177 Nd9d1f750d17443ba84b60b40a21fc2cd rdf:first sg:person.0610157125.40
    178 rdf:rest rdf:nil
    179 Nda7a6752c4364ee2b487d6a0863ea139 schema:name readcube_id
    180 schema:value bf4da7be9c02e5e7619ca2741587d5d28bef0107bf1d8c504eb2b9406e99bfd5
    181 rdf:type schema:PropertyValue
    182 Nddef86f435654768ab0e3924d1caef4b rdf:first sg:person.01224603156.65
    183 rdf:rest N8492f691b3384d2ea8d23af7646cf838
    184 Ne0b3aad79c5d4249a3f98f25637ff014 rdf:first Ne42d5cfe687f46b0bb5065e8a71a8a1e
    185 rdf:rest N60c5a23bdcb742849fc5e1d4fa221d38
    186 Ne42d5cfe687f46b0bb5065e8a71a8a1e schema:familyName Brzezinski
    187 schema:givenName Amnon
    188 rdf:type schema:Person
    189 Nef7d397f30244d6e947b7f75fdd00e0e schema:familyName Srinivasan
    190 schema:givenName V.
    191 rdf:type schema:Person
    192 Nfcdcc4fd5b7947a9b6895f0285137d53 rdf:first sg:person.01237721775.15
    193 rdf:rest N844caf43772645d29ddd58509be7cd92
    194 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    195 schema:name Medical and Health Sciences
    196 rdf:type schema:DefinedTerm
    197 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
    198 schema:name Cardiorespiratory Medicine and Haematology
    199 rdf:type schema:DefinedTerm
    200 sg:person.01174461275.76 schema:affiliation https://www.grid.ac/institutes/grid.4280.e
    201 schema:familyName Kaur
    202 schema:givenName Charanjit
    203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174461275.76
    204 rdf:type schema:Person
    205 sg:person.01224603156.65 schema:affiliation https://www.grid.ac/institutes/grid.11875.3a
    206 schema:familyName Zakaria
    207 schema:givenName Rahimah
    208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224603156.65
    209 rdf:type schema:Person
    210 sg:person.01237721775.15 schema:affiliation N8bd1cf1d4a3e42b58c9e8aabea2425f2
    211 schema:familyName Srinivasan
    212 schema:givenName Venkataramanujam
    213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237721775.15
    214 rdf:type schema:Person
    215 sg:person.01341031556.31 schema:affiliation https://www.grid.ac/institutes/grid.428821.5
    216 schema:familyName Othman
    217 schema:givenName Zahiruddin
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341031556.31
    219 rdf:type schema:Person
    220 sg:person.0604043132.25 schema:affiliation https://www.grid.ac/institutes/grid.460829.1
    221 schema:familyName Srinivasan
    222 schema:givenName U. S.
    223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604043132.25
    224 rdf:type schema:Person
    225 sg:person.0610157125.40 schema:affiliation N71d0f933d1894fe7bdc5a9d8ef928421
    226 schema:familyName Acuña-Castroviejo
    227 schema:givenName Dario
    228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610157125.40
    229 rdf:type schema:Person
    230 sg:person.0632502703.19 schema:affiliation https://www.grid.ac/institutes/grid.259906.1
    231 schema:familyName Lauterbach
    232 schema:givenName Edward C.
    233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632502703.19
    234 rdf:type schema:Person
    235 sg:pub.10.1007/bf03033887 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051841365
    236 https://doi.org/10.1007/bf03033887
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1007/s00401-007-0193-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018593035
    239 https://doi.org/10.1007/s00401-007-0193-x
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1007/s00401-009-0538-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000508964
    242 https://doi.org/10.1007/s00401-009-0538-8
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1007/s00415-006-0390-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1035100308
    245 https://doi.org/10.1007/s00415-006-0390-x
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1007/s00415-008-0629-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050412882
    248 https://doi.org/10.1007/s00415-008-0629-9
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1007/s10549-007-9617-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008876587
    251 https://doi.org/10.1007/s10549-007-9617-5
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1023/a:1025682611389 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043134078
    254 https://doi.org/10.1023/a:1025682611389
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1023/b:jobb.0000041771.66775.d5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032430633
    257 https://doi.org/10.1023/b:jobb.0000041771.66775.d5
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1023/b:nere.0000014827.94562.4b schema:sameAs https://app.dimensions.ai/details/publication/pub.1044554912
    260 https://doi.org/10.1023/b:nere.0000014827.94562.4b
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1038/70978 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031949261
    263 https://doi.org/10.1038/70978
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1186/1742-4933-2-17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033294837
    266 https://doi.org/10.1186/1742-4933-2-17
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1385/endo:27:2:101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010104011
    269 https://doi.org/10.1385/endo:27:2:101
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1385/mn:27:3:325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017950416
    272 https://doi.org/10.1385/mn:27:3:325
    273 rdf:type schema:CreativeWork
    274 https://app.dimensions.ai/details/publication/pub.1075238442 schema:CreativeWork
    275 https://app.dimensions.ai/details/publication/pub.1077115998 schema:CreativeWork
    276 https://app.dimensions.ai/details/publication/pub.1078042032 schema:CreativeWork
    277 https://app.dimensions.ai/details/publication/pub.1078148550 schema:CreativeWork
    278 https://app.dimensions.ai/details/publication/pub.1079238655 schema:CreativeWork
    279 https://doi.org/10.1001/archneurol.2010.135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049943065
    280 rdf:type schema:CreativeWork
    281 https://doi.org/10.1002/1531-8257(199911)14:6<922::aid-mds1003>3.0.co;2-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045836851
    282 rdf:type schema:CreativeWork
    283 https://doi.org/10.1002/1531-8257(200007)15:4<669::aid-mds1011>3.0.co;2-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001957187
    284 rdf:type schema:CreativeWork
    285 https://doi.org/10.1002/ana.410320616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032351171
    286 rdf:type schema:CreativeWork
    287 https://doi.org/10.1002/ana.410320703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049607259
    288 rdf:type schema:CreativeWork
    289 https://doi.org/10.1002/jnr.22123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030598008
    290 rdf:type schema:CreativeWork
    291 https://doi.org/10.1002/mds.10167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016472005
    292 rdf:type schema:CreativeWork
    293 https://doi.org/10.1002/mds.10425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011012863
    294 rdf:type schema:CreativeWork
    295 https://doi.org/10.1002/mds.10429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042332707
    296 rdf:type schema:CreativeWork
    297 https://doi.org/10.1006/nbdi.2000.0319 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050210436
    298 rdf:type schema:CreativeWork
    299 https://doi.org/10.1016/0006-8993(95)96872-i schema:sameAs https://app.dimensions.ai/details/publication/pub.1003490623
    300 rdf:type schema:CreativeWork
    301 https://doi.org/10.1016/0278-5846(89)90052-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014508056
    302 rdf:type schema:CreativeWork
    303 https://doi.org/10.1016/0891-5849(91)90009-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1048468249
    304 rdf:type schema:CreativeWork
    305 https://doi.org/10.1016/0896-6273(94)90055-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007737076
    306 rdf:type schema:CreativeWork
    307 https://doi.org/10.1016/j.bbabio.2004.03.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024589442
    308 rdf:type schema:CreativeWork
    309 https://doi.org/10.1016/j.bbrc.2007.01.063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036675623
    310 rdf:type schema:CreativeWork
    311 https://doi.org/10.1016/j.brainres.2005.04.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000858007
    312 rdf:type schema:CreativeWork
    313 https://doi.org/10.1016/j.brainres.2005.05.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006963030
    314 rdf:type schema:CreativeWork
    315 https://doi.org/10.1016/j.brainres.2005.09.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015162168
    316 rdf:type schema:CreativeWork
    317 https://doi.org/10.1016/j.brainresbull.2009.12.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002072864
    318 rdf:type schema:CreativeWork
    319 https://doi.org/10.1016/j.clineuro.2010.02.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018043686
    320 rdf:type schema:CreativeWork
    321 https://doi.org/10.1016/j.molbrainres.2005.01.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024496041
    322 rdf:type schema:CreativeWork
    323 https://doi.org/10.1016/j.neuint.2005.12.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003975223
    324 rdf:type schema:CreativeWork
    325 https://doi.org/10.1016/j.neulet.2008.04.099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026400208
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.1016/j.neuropharm.2004.09.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015323986
    328 rdf:type schema:CreativeWork
    329 https://doi.org/10.1016/j.parkreldis.2003.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004893527
    330 rdf:type schema:CreativeWork
    331 https://doi.org/10.1016/j.pharmthera.2005.05.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019297141
    332 rdf:type schema:CreativeWork
    333 https://doi.org/10.1016/j.psc.2004.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011812038
    334 rdf:type schema:CreativeWork
    335 https://doi.org/10.1016/j.sleep.2003.10.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019767897
    336 rdf:type schema:CreativeWork
    337 https://doi.org/10.1016/j.sleep.2004.07.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001437775
    338 rdf:type schema:CreativeWork
    339 https://doi.org/10.1016/j.sleep.2005.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026795733
    340 rdf:type schema:CreativeWork
    341 https://doi.org/10.1016/j.smrv.2004.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021691158
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1016/s0006-8993(02)02551-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029611554
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1016/s0024-3205(96)00606-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021754734
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1016/s0031-9384(99)00023-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006921373
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1016/s0047-6374(01)00384-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051854029
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1016/s0140-6736(95)92509-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018935078
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1016/s0197-4580(02)00065-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016528708
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1016/s0197-4580(02)00133-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025321879
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1016/s0896-6273(00)80350-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014431501
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1016/s1353-8020(99)00011-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043332117
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1017/s1092852900017260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039906993
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.1021/jm050740o schema:sameAs https://app.dimensions.ai/details/publication/pub.1055949781
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.1034/j.1600-079x.2002.00841.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026911239
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.1046/j.1432-1033.2003.03430.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1012287438
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1046/j.1600-079x.2003.00096.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053658959
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1053/smrv.2002.0229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038357272
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1073/pnas.92.19.8734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046904595
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1074/jbc.m005141200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007184475
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1080/07420520701420717 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029868898
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1080/07420520701672556 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040978198
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1093/brain/123.2.331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005311422
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1093/brain/awm056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049085482
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1093/brain/awm097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042667052
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1093/brain/awp263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009697029
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1093/emboj/20.15.3967 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049155093
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1093/nar/23.3.327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008722740
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1093/nar/gks630 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029712603
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1096/fj.00-0129com schema:sameAs https://app.dimensions.ai/details/publication/pub.1012463277
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1097/00000542-200610000-00029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015335369
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1097/00001756-199812210-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015705916
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1097/00002826-198812000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044203673
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1097/00002826-200207000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016612946
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1097/jgp.0b013e3181e448f7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009083847
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1101/gad.1432206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035678621
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1111/j.1468-1331.2009.02848.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021713266
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1111/j.1471-4159.1989.tb09133.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000702028
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1111/j.1600-079x.1997.tb00342.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018959243
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1111/j.1600-079x.2005.00282.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044515150
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1111/j.1600-079x.2006.00412.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030904485
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1111/j.1600-079x.2009.00713.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050553140
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1111/j.1600-079x.2010.00819.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009754331
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1111/j.1742-4658.2008.06302.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018716415
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1111/j.1749-6632.1985.tb11825.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033809071
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1113/jphysiol.2004.073742 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051713165
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1159/000148191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046546461
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1176/jnp.2010.22.1.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063512791
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1176/jnp.2010.22.2.130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063512795
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1177/0891988704267465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010065397
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1177/1534735408322846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024061881
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1182/blood-2003-03-0779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000085349
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1210/edrv-1-2-109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064237851
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1212/01.wnl.0000179346.39655.e0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064347486
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1212/01.wnl.0000278114.14096.74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064349648
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1212/wnl.0b013e3181ebdd79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036067209
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1212/wnl.46.2.388 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064373688
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1212/wnl.58.7.1019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064380729
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1515/revneuro.2008.19.4-5.245 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039049444
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.2147/ndt.s4578 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000788272
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.2174/1568026023394335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069192858
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.2174/1568026023394407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069192862
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.2174/187152712800269740 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069221718
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.3109/09513590903159649 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028969499
    464 rdf:type schema:CreativeWork
    465 https://www.grid.ac/institutes/grid.11875.3a schema:alternateName Universiti Sains Malaysia
    466 schema:name Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 16150, Malaysia
    467 rdf:type schema:Organization
    468 https://www.grid.ac/institutes/grid.259906.1 schema:alternateName Mercer University
    469 schema:name Department of Psychiatry and Behavioral Sciences and the Department of Internal Medicine, Neurology Section, Mercer University School of Medicine, 655 First Street, Macon, GA 31201, USA
    470 rdf:type schema:Organization
    471 https://www.grid.ac/institutes/grid.4280.e schema:alternateName National University of Singapore
    472 schema:name Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, BLK MD 10, 4 Medical Drive, Singapore, 117597, Singapore
    473 rdf:type schema:Organization
    474 https://www.grid.ac/institutes/grid.428821.5 schema:alternateName Hospital Universiti Sains Malaysia
    475 schema:name Department of Psychiatry, School of Medical Sciences, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, 16150, Malaysia
    476 rdf:type schema:Organization
    477 https://www.grid.ac/institutes/grid.460829.1 schema:alternateName Fortis Malar Hospital
    478 schema:name Department of Neurosurgery, Fortis Malar Hospital, Gandhi Nagar Main Road, Adyar, Chennai, TN, 600020, India
    479 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...