Transmission of Hepatitis C Virus Through Needlestick Accidents in Health Care Workers View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1994

AUTHORS

Takeshi Sodeyama , Kendo Kiyosawa , Akihiko Urushihara , Akihiro Matsumoto , Eiji Tanaka , Seiichi Furuta , Masashi Mizokami , Yoshihiro Akahane

ABSTRACT

Viral infection through needlestick accidents is a serious problem among health care workers. We evaluated the actual transmission of hepatitis C virus (HCV) infection through needlestick accidents using second-generation HCV antibody and HCV-RNA tests. Of 92 needlestick accidents involving patients with non-A, non-B (NANB) hepatitis, acute hepatitis NANB developed in three recipients. All three index donors were positive for HCV-RNA. Two of the three recipients became HCV-RNA positive and seroconverted to anti-HCV. The genotype of HCV-RNA in each donor-recipient pair was identical. One of the two pairs showed a high homology of HCV-RNA nucleotide sequences. When the donor patients were positive for anti-HCV-2 or HCV-RNA, the incidence of HCV infection after needlestick accident was 1.2% or 1.4%, respectively. Though this transmission rate is not necessarily high, needlestick accident is an apparent HCV transmission route, and appropriate precautions in hospital employees and careful follow-up of such accidents are needed. More... »

PAGES

459-462

References to SciGraph publications

Book

TITLE

Viral Hepatitis and Liver Disease

ISBN

978-4-431-68257-8
978-4-431-68255-4

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-4-431-68255-4_117

DOI

http://dx.doi.org/10.1007/978-4-431-68255-4_117

DIMENSIONS

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