Ontology type: schema:Chapter
1998
AUTHORSByoung Goo Min , Jae Mok Ahn , Chan Young Park , Yung Ho Jo , Won Woo Choi , Hyun Jung Kim , Seong Keun Park , Jong Jin Lee , Jae Soon Choi , Kyong Sik , Jongwon Kim , Jun Keun Chang , Hee Chan Kim , Won Gon Kim , Joon Ryang Roh , Yong Soon Won
ABSTRACTThe electromechanical total artificial heart (TAH) developed at Seoul National University Hospital was verified as acceptable for human implantation through several successful animal experiments. In the last two years (1994–1996), the TAH was redesigned to be small (600–650 ml, total volume) and lightweight (approimately 950 g), and also improved to overcome three practical problems encountered in the animal experiments. First, we implemented modifications to the blood-pump housing to resolve the anatomical problem made apparent through the construction of a three-dimensional model of the TAH, the human thoracic cavity, and the large vessels, from magnetic resonance images and Angiogram-Computer tomography. Second, the intraventricular surface of the blood sacs was modified with fibrinolytic and anti-infective surface treatments. Third, the mechanism of regulation of cardiac output (CO) was improved by analyzing the measured pressure in the interventricular volume space (IVP). It proved beneficial to achieve the regulation of CO in response to the physiological demand, and to prevent atrial collapse due to the suction. The IVP, which accurately reflected the hemodynamic parameters, was used to predict the preload condition. These three improvements will assist in the application of the newly developed implantable electromechanical artificial heart for long-term implantation. More... »
PAGES331-336
Heart Replacement
ISBN
978-4-431-65923-5
978-4-431-65921-1
http://scigraph.springernature.com/pub.10.1007/978-4-431-65921-1_48
DOIhttp://dx.doi.org/10.1007/978-4-431-65921-1_48
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