Ontology type: schema:Chapter
2008
AUTHORSRalf Bartenschlager , Gang Long , Darius Moradpour
ABSTRACTChronic liver disease caused by infection with the hepatitis C virus (HCV) is an important medical problem. Although primary infection usually is mild, and often asymptomatic, in the vast majority of cases HCV establishes persistence that in the course of one or several decades may result in chronic liver diseases including liver cirrhosis and hepatocellular carcinoma. Therapeutic options are limited and a vaccine to prevent HCV infection is not in sight. Diagnostic tests to detect HCV-containing blood products have become available after the first molecular cloning of the viral genome. This achievement also opened the field for studies of the viral replication cycle as well as the development of selective antiviral drugs. HCV is a hepatotropic flavivirus which has several remarkable properties. Among these are the potent inhibition of the induction phase of the innate antiviral response, the high genomic plasticity and the unusual strategy of virus particle assembly that occurs in close association with lipid droplets and the very-low-density lipoprotein production pathway. This chapter will briefly summarise some old and new aspects of chronic hepatitis C and of the pathogen responsible for this disease. More... »
PAGES95-120
Comparative Hepatitis
ISBN
978-3-7643-8557-6
978-3-7643-8558-3
http://scigraph.springernature.com/pub.10.1007/978-3-7643-8558-3_5
DOIhttp://dx.doi.org/10.1007/978-3-7643-8558-3_5
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"publisher": {
"location": "Basel",
"name": "Birkh\u00e4user Basel",
"type": "Organisation"
},
"sameAs": [
"https://doi.org/10.1007/978-3-7643-8558-3_5",
"https://app.dimensions.ai/details/publication/pub.1007171382"
],
"sdDataset": "chapters",
"sdDatePublished": "2019-04-16T06:11",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000350_0000000350/records_77581_00000000.jsonl",
"type": "Chapter",
"url": "https://link.springer.com/10.1007%2F978-3-7643-8558-3_5"
}
]Download the RDF metadata as:Â json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-7643-8558-3_5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-7643-8558-3_5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-7643-8558-3_5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-7643-8558-3_5'
This table displays all metadata directly associated to this object as RDF triples.
583 TRIPLES
23 PREDICATES
190 URIs
20 LITERALS
8 BLANK NODES