Burn reconstruction: Skin substitutes and tissue engineering View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Raymund E. Horch , Volker J. Schmidt

ABSTRACT

Skin, also known as the integument, is not only the largest laminar organ, but also the appropriate interface between the human organism and its environment. Beside other functions the skin represents the primary barrier of the immune system. Thus, an extensive skin loss due to thermal trauma represents in the majority of cases a life-threatening situation and demands particular requirements from the Plastic and Burn surgery to provide a sufficient skin substitution. Development and improvement of innovative strategies concerning skin expansion and Tissue Engineering have contributed to the fact that burns affecting more than 80 % of the body surface (TBS) are survivable today [110]. Although the application of cultured epidermis and compound cultured skin analogues is approved as a life-saving method today, the indications for this novel approach have become more differentiated. Beside historical aspects the present chapter gives insights into both the conventional techniques and the application forms of current cultured skin substitutes. More... »

PAGES

149-167

Book

TITLE

Handbook of Burns

ISBN

978-3-7091-0314-2
978-3-7091-0315-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-7091-0315-9_13

DOI

http://dx.doi.org/10.1007/978-3-7091-0315-9_13

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028805980


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