Progression of Chronic Kidney Disease and Nephroprotective Therapy View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Elke Wühl , Franz Schaefer

ABSTRACT

Progression of childhood chronic kidney disease towards end-stage renal failure is common and once a significant impairment of renal function has occurred renal failure tends to progress almost irrespectively of the type of underlying kidney disease. The phenomenon of renal failure progression following kidney injury or maldevelopment is a current focus of renal research in adults and children. There is clear evidence from clinical studies that hypertension and proteinuria are key players in the pathophysiology of CKD progression in humans. The renin-angiotensin system is intrinsically involved in the process; presumed modifiers of disease progression include the genetic background, altered mineral homeostasis, anemia, metabolic acidosis, dyslipidemia, inflammation and oxidative stress, on top of general cardiovascular risk factors such as diabetes, smoking and obesity. This chapter summarizes the current state of knowledge regarding the pathophysiology of renal disease progression and discusses the evidence base of renoprotective strategies in pediatric CKD. More... »

PAGES

1399-1423

References to SciGraph publications

  • 2004-06. Renoprotection by ACE inhibitors after severe hemolytic uremic syndrome in PEDIATRIC NEPHROLOGY
  • 2013-10. Is obesity a risk factor for chronic kidney disease in children? in PEDIATRIC NEPHROLOGY
  • 2012-10. Update on fibroblast growth factor 23 in chronic kidney disease in KIDNEY INTERNATIONAL
  • 1999-11. Effect of metabolic acidosis on hyperlipidemia in uremia in PEDIATRIC NEPHROLOGY
  • 1998-05. 1,25-Dihydroxyvitamin D3 corrects insulin and lipid abnormalities in uremia in KIDNEY INTERNATIONAL
  • 2000-01. ACE genotype and ACE inhibitors induced renoprotection in chronic proteinuric nephropathies1 in KIDNEY INTERNATIONAL
  • 2001-04. Polymorphisms of renin-angiotensin system genes in childhood IgA nephropathy in PEDIATRIC NEPHROLOGY
  • 2003-04. Proteinuria and the risk of developing end-stage renal disease in KIDNEY INTERNATIONAL
  • 2014-06. KDIGO Clinical Practice Guideline for Lipid Management in CKD: summary of recommendation statements and clinical approach to the patient in KIDNEY INTERNATIONAL
  • 1998-06. Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation in KIDNEY INTERNATIONAL
  • 2012-11. Educational Paper: Progression in chronic kidney disease and prevention strategies in EUROPEAN JOURNAL OF PEDIATRICS
  • 2004-08. Antihypertensive and antiproteinuric efficacy of ramiprilin children with chronic renal failure in KIDNEY INTERNATIONAL
  • 2006-05. Angiotensin II production and distribution in the kidney – II. Model-based analysis of experimental data in KIDNEY INTERNATIONAL
  • 1994-06. Tubular catabolism of albumin is associated with the release of an inflammatory lipid in KIDNEY INTERNATIONAL
  • 1997-01. Understanding the nature of renal disease progression in KIDNEY INTERNATIONAL
  • 2004-10. Utility of 24-h ambulatory blood pressure measurement in a routine clinical setting of patients with chronic renal disease in JOURNAL OF HUMAN HYPERTENSION
  • 1992-09. Prognosis of patients with unilateral renal agenesis in PEDIATRIC NEPHROLOGY
  • 2013-02. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations in NATURE GENETICS
  • 2007-07. Progression of chronic renal failure in children with dysplastic kidneys in PEDIATRIC NEPHROLOGY
  • 2000-07. Plasma lipids and risk of developing renal dysfunction: The Atherosclerosis Risk in Communities Study in KIDNEY INTERNATIONAL
  • 2009-09. Renal outcome in patients with congenital anomalies of the kidney and urinary tract in KIDNEY INTERNATIONAL
  • 2007-08. Appropriate blood pressure control in hypertensive and normotensive type 2 diabetes mellitus: a summary of the ABCD trial in NATURE REVIEWS NEPHROLOGY
  • 2006-05. Angiotensin II production and distribution in the kidney: I. A kinetic model in KIDNEY INTERNATIONAL
  • 2004-02. Proteinuria as a predictor of disease progression in children with hypodysplastic nephropathy in PEDIATRIC NEPHROLOGY
  • 1998-10. Metabolic effects of erythropoietin in patients on peritoneal dialysis in PEDIATRIC NEPHROLOGY
  • 2003-06. Retarding progression of chronic renal disease: The neglected issue of residual proteinuria in KIDNEY INTERNATIONAL
  • 2001-07. The natural history of renal disease in Australian Aborigines. Part 1. Changes in albuminuria and glomerular filtration rate over time in KIDNEY INTERNATIONAL
  • 2002-05. Effect of combining ACE inhibitor and statin in severe experimental nephropathy in KIDNEY INTERNATIONAL
  • 2010-05. New loci associated with kidney function and chronic kidney disease in NATURE GENETICS
  • 2000-01. Angiotensin II increases the intracellular calcium activity in podocytes of the intact glomerulus in KIDNEY INTERNATIONAL
  • 2004. Hypertension in Chronic Kidney Disease in PEDIATRIC HYPERTENSION
  • 1997-09. Hypoxia stimulates proximal tubular cell matrix production via a TGF-β1-independent mechanism in KIDNEY INTERNATIONAL
  • 1998-08. Effect of metabolic acidosis on insulin action and secretion in uremia in KIDNEY INTERNATIONAL
  • 2007-08. Podocyte protection by darbepoetin: preservation of the cytoskeleton and nephrin expression in KIDNEY INTERNATIONAL
  • 2007-09. The incidence and implications of aldosterone breakthrough in NATURE REVIEWS NEPHROLOGY
  • 1997-09. Angiotensin II increases the cytosolic calcium activity in rat podocytes in culture in KIDNEY INTERNATIONAL
  • 1997-01. Twenty-four-hour ambulatory blood pressure profiles in pediatric patients after renal transplantation in PEDIATRIC NEPHROLOGY
  • 1992-08. Long-term comparison between captopril and nifedipine in the progression of renal insufficiency in KIDNEY INTERNATIONAL
  • 1914. Die Brightsche Nierenkrankheit, Klinik, Pathologie und Atlas in NONE
  • 2004-07. Is ACE gene polymorphism a risk factor for renal scarring with low-grade reflux? in PEDIATRIC NEPHROLOGY
  • 2002-03. Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes in KIDNEY INTERNATIONAL
  • 1999-07. ACE I/D gene polymorphism predicts renal damage in congenital uropathies in PEDIATRIC NEPHROLOGY
  • Book

    TITLE

    Pediatric Kidney Disease

    ISBN

    978-3-662-52970-6
    978-3-662-52972-0

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-662-52972-0_53

    DOI

    http://dx.doi.org/10.1007/978-3-662-52972-0_53

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1083875606


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