TrypZean™: An Animal-Free Alternative to Bovine Trypsin View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

Aparna Krishnan , Susan L. Woodard

ABSTRACT

Trypsin derived from either porcine or bovine pancreas is widely used in biopharmaceutical manufacturing. This industry is working toward replacing animal source materials with alternatives to prevent contamination of the products with mammalian viruses and human pathogens. Bovine trypsin made in maize seed culminated in a commercial product, TrypZean™, which is a possible replacement product for use in cell culture and viral vaccine manufacturing, as well as in the processing of therapeutic proteins. This chapter describes the development of this product from a plant biotechnology perspective and then discusses how it is being used today. Possible improvements to make this product more cost competitive are discussed. More... »

PAGES

43-63

Book

TITLE

Commercial Plant-Produced Recombinant Protein Products

ISBN

978-3-662-43835-0
978-3-662-43836-7

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-662-43836-7_4

DOI

http://dx.doi.org/10.1007/978-3-662-43836-7_4

DIMENSIONS

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