Application du Modele de Cox a l’Etablissement d’une Classification Pronostique de la Deterioration Intellectuelle dans la Maladie de Parkinson View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1981

AUTHORS

Jean-Louis Golmard , Alain Guillard , Claude Chastang

ABSTRACT

L DOPA which reduces akinetic symtoms has also prolonged the survival time of Parkinson patients but as a consequence mental deterioration can be observed in some patients. Thus the aim of our study is to determine what parameters could allow a prognosis of Parkinson intellectual performances patients. For this purpose, 244 patients have been followed for periods ranging from 4 to 11 years after the beginning of the DOPA therapy. The statistical methodology involved both actuarial method and Cox’s model for censored data. So far our main results can be summerized as follow : three classes of patients were determined : i. a hight-risk group exhibiting transitory psychotic symtoms during the first year of DOPA therapy ; ii. a low-risk group with only a tremor at the begining of the therapy or an age less than 60 years, and iii. the remaining patients constitute the intermediary-risk group. More... »

PAGES

629-636

Book

TITLE

Medical Informatics Europe 81

ISBN

978-3-540-10568-8
978-3-642-93169-7

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-93169-7_83

DOI

http://dx.doi.org/10.1007/978-3-642-93169-7_83

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016292591


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