Injectable Bone Graft in Rabbit Radius Defects: Influence of Demineralized Bone Matrix, Bone Marrow and Cancellous Bone View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1989

AUTHORS

K. G. Thorngren , P. Aspenberg , J. Wittbjer

ABSTRACT

Injectable bone transplants would be useful in a variety of conditions requiring local stimulation of bone formation. Apart from bone defects after resection, for example in tumour surgery, conditions requiring extra stimulation to form callus, as in slow-healing fractures, could be percutaneously grafted. Apart from by a direct percutaneous approach, injectable bone grafting could be achieved using a tube, such as a cannulated rush-pin, inserted into the medullary canal of a long bone from a safe distance. An injectable bone transplant should then consist of agents previously known to stimulate the bone formation. Demineralized bone matrix has been shown to contain such factors. To allow a percutaneous application it must be particulated. Bone marrow cells have been shown to increase bone formation in connection with bone matrix both by their own bone-forming capacity and by increasing the supply of undifferentiated target cells for the inductive factors [1]. The present study compares pulverized bone matrix and autologus bone marrow with conventionally implanted whole bone matrix and marrow or cancellous bone. More... »

PAGES

214-215

Book

TITLE

Bone Transplantation

ISBN

978-3-642-83573-5
978-3-642-83571-1

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-83571-1_38

DOI

http://dx.doi.org/10.1007/978-3-642-83571-1_38

DIMENSIONS

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