Regulation of mouse mammary tumor virus gene expression by glucocorticoid hormones. View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1979

AUTHORS

H E Varmus , G Ringold , K R Yamamoto

ABSTRACT

Several laboratories have documented that glucocorticoid hormones markedly stimulate the expression of mouse mammary tumor virus genes in a variety of mouse mammary tumor cells and in infected heterologous cells. The effect of the hormone appears to be a rapid and specific augmentation of the synthesis of viral RNA, mediated by interaction with glucocorticoid receptor proteins. The availability of virus-specific reagents and recent developments in the molecular biology of RNA tumor viruses now permit a highly refined analysis of hormonal regulation in this experimental system. More... »

PAGES

253-78

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-81265-1_14

DOI

http://dx.doi.org/10.1007/978-3-642-81265-1_14

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1078575993

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/226870


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