In vitro Interactions Between Tumor Cells and Immune Lymphoid Cells View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1976

AUTHORS

J. P. Levy , E. Gomard , A. Senik , J. C. Leclerc

ABSTRACT

In the past 6 years after the very important initial contribution of HELLSTRÖM (11), about 100 papers have been published, reporting the existence of tumor-specific, cell-mediated immune reactions (CMIR) in man. Now, in the last 2 years, several groups have clearly demonstrated that most, and perhaps all, of these results are not related to the anti-tumor response, since they also exist in controls at the same level and with the same frequency (3, 5, 20, 29). In fact, no attention has been given to the nature of the effector cell or to their specificity in many of the experiments reported. Perhaps it is useful to return to clear experimental models to try to etablish the significance of the in vitro methods used in investigations on cell-mediated antitumor immunity, and to determine whether the anti-tumor immune response is actually a response against the tumor or in fact an intercurrent phenomenon. More... »

PAGES

24-30

Book

TITLE

Lymphocytes, Macrophages, and Cancer

ISBN

978-3-642-81051-0
978-3-642-81049-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-81049-7_4

DOI

http://dx.doi.org/10.1007/978-3-642-81049-7_4

DIMENSIONS

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