Mechanical Ventilation should be Individually Optimized in Patients with ARDS View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1995

AUTHORS

F. Brunet , J. F. Dhainaut , J. Dall’ava-Santucci

ABSTRACT

The mortality of the adult respiratory distress syndrome (ARDS) remains high, but patients who survived the acute phase of the syndrome generally resume productive lives with no serious pulmonary limitations [1–3]. Specific treatments of ARDS should ideally be directed to limit the initial abnormal inflammatory response. However, ARDS therapy is essentially supportive with a central role for mechanical ventilation. Conventional mode of ventilation aimed to obtain “normal” pulmonary function as reflected by arterial blood gases, and some lung injury was accepted as an inevitable consequence [4, 5]. Positive-end expiratory pressure (PEEP) has been early proposed to achieve adequate arterial oxygenation while decreasing FiO2 to limit oxygen toxicity [4, 5]. This type of ventilatory support is frequently associated with high airway pressures and volumes for effective ventilation which, in turn, may worsen the lung injury [7–11]. Optimal ventilation would be the mode achieving adequate gas exchange without increasing the risk of ventilator-induced barotrauma [7, 12]. New strategies have been developed to prevent the lungs exposure to high pressures and to lower minute ventilation [13–15]. All these modes of ventilation introduce a new concept of ventilation which allows “abnormal” respiratory function with hypercapnia [12, 16]. There are no convincing data indicating that any ventilatory mode is superior to others for ARDS patients, both in terms of reduction of morbidity and mortality. More... »

PAGES

81-88

Book

TITLE

Yearbook of Intensive Care and Emergency Medicine

ISBN

978-3-540-58256-4
978-3-642-79154-3

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-79154-3_8

DOI

http://dx.doi.org/10.1007/978-3-642-79154-3_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050255509


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Brunet", 
        "givenName": "F.", 
        "id": "sg:person.0741664152.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741664152.85"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Dhainaut", 
        "givenName": "J. F.", 
        "id": "sg:person.0737311472.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737311472.48"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Dall\u2019ava-Santucci", 
        "givenName": "J.", 
        "id": "sg:person.0656355071.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656355071.53"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1995", 
    "datePublishedReg": "1995-01-01", 
    "description": "The mortality of the adult respiratory distress syndrome (ARDS) remains high, but patients who survived the acute phase of the syndrome generally resume productive lives with no serious pulmonary limitations [1\u20133]. Specific treatments of ARDS should ideally be directed to limit the initial abnormal inflammatory response. However, ARDS therapy is essentially supportive with a central role for mechanical ventilation. Conventional mode of ventilation aimed to obtain \u201cnormal\u201d pulmonary function as reflected by arterial blood gases, and some lung injury was accepted as an inevitable consequence [4, 5]. Positive-end expiratory pressure (PEEP) has been early proposed to achieve adequate arterial oxygenation while decreasing FiO2 to limit oxygen toxicity [4, 5]. This type of ventilatory support is frequently associated with high airway pressures and volumes for effective ventilation which, in turn, may worsen the lung injury [7\u201311]. Optimal ventilation would be the mode achieving adequate gas exchange without increasing the risk of ventilator-induced barotrauma [7, 12]. New strategies have been developed to prevent the lungs exposure to high pressures and to lower minute ventilation [13\u201315]. All these modes of ventilation introduce a new concept of ventilation which allows \u201cabnormal\u201d respiratory function with hypercapnia [12, 16]. There are no convincing data indicating that any ventilatory mode is superior to others for ARDS patients, both in terms of reduction of morbidity and mortality.", 
    "editor": [
      {
        "familyName": "Vincent", 
        "givenName": "Jean-Louis", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-642-79154-3_8", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-540-58256-4", 
        "978-3-642-79154-3"
      ], 
      "name": "Yearbook of Intensive Care and Emergency Medicine", 
      "type": "Book"
    }, 
    "keywords": [
      "adult respiratory distress syndrome", 
      "positive-end expiratory pressure", 
      "lung injury", 
      "mechanical ventilation", 
      "ventilator-induced barotrauma", 
      "high airway pressures", 
      "lower minute ventilation", 
      "respiratory distress syndrome", 
      "arterial blood gases", 
      "abnormal inflammatory response", 
      "adequate arterial oxygenation", 
      "mode of ventilation", 
      "adequate gas exchange", 
      "ARDS therapy", 
      "ventilatory support", 
      "airway pressure", 
      "pulmonary limitations", 
      "pulmonary function", 
      "arterial oxygenation", 
      "ARDS patients", 
      "distress syndrome", 
      "acute phase", 
      "expiratory pressure", 
      "blood gases", 
      "minute ventilation", 
      "ventilatory mode", 
      "inflammatory response", 
      "respiratory function", 
      "lung exposure", 
      "specific treatment", 
      "convincing data", 
      "patients", 
      "effective ventilation", 
      "optimal ventilation", 
      "ventilation", 
      "oxygen toxicity", 
      "syndrome", 
      "injury", 
      "mortality", 
      "terms of reduction", 
      "productive life", 
      "gas exchange", 
      "morbidity", 
      "FiO2", 
      "hypercapnia", 
      "barotrauma", 
      "therapy", 
      "central role", 
      "inevitable consequence", 
      "oxygenation", 
      "new strategy", 
      "treatment", 
      "risk", 
      "pressure", 
      "toxicity", 
      "exposure", 
      "response", 
      "function", 
      "life", 
      "role", 
      "conventional mode", 
      "reduction", 
      "volume", 
      "data", 
      "consequences", 
      "support", 
      "strategies", 
      "types", 
      "limitations", 
      "new concept", 
      "turn", 
      "phase", 
      "mode", 
      "terms", 
      "exchange", 
      "concept", 
      "gases", 
      "high pressure", 
      "serious pulmonary limitations", 
      "initial abnormal inflammatory response"
    ], 
    "name": "Mechanical Ventilation should be Individually Optimized in Patients with ARDS", 
    "pagination": "81-88", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050255509"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-642-79154-3_8"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-642-79154-3_8", 
      "https://app.dimensions.ai/details/publication/pub.1050255509"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-01-01T19:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/chapter/chapter_391.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-3-642-79154-3_8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-79154-3_8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-79154-3_8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-79154-3_8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-79154-3_8'


 

This table displays all metadata directly associated to this object as RDF triples.

148 TRIPLES      23 PREDICATES      106 URIs      99 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-642-79154-3_8 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author Nea94ae528c1f41b3a9436206ac4a2cf1
4 schema:datePublished 1995
5 schema:datePublishedReg 1995-01-01
6 schema:description The mortality of the adult respiratory distress syndrome (ARDS) remains high, but patients who survived the acute phase of the syndrome generally resume productive lives with no serious pulmonary limitations [1–3]. Specific treatments of ARDS should ideally be directed to limit the initial abnormal inflammatory response. However, ARDS therapy is essentially supportive with a central role for mechanical ventilation. Conventional mode of ventilation aimed to obtain “normal” pulmonary function as reflected by arterial blood gases, and some lung injury was accepted as an inevitable consequence [4, 5]. Positive-end expiratory pressure (PEEP) has been early proposed to achieve adequate arterial oxygenation while decreasing FiO2 to limit oxygen toxicity [4, 5]. This type of ventilatory support is frequently associated with high airway pressures and volumes for effective ventilation which, in turn, may worsen the lung injury [7–11]. Optimal ventilation would be the mode achieving adequate gas exchange without increasing the risk of ventilator-induced barotrauma [7, 12]. New strategies have been developed to prevent the lungs exposure to high pressures and to lower minute ventilation [13–15]. All these modes of ventilation introduce a new concept of ventilation which allows “abnormal” respiratory function with hypercapnia [12, 16]. There are no convincing data indicating that any ventilatory mode is superior to others for ARDS patients, both in terms of reduction of morbidity and mortality.
7 schema:editor N3c2ddad80117466db7b4cef359806d1a
8 schema:genre chapter
9 schema:inLanguage en
10 schema:isAccessibleForFree false
11 schema:isPartOf Na1d58fff9aae497b9b3c6ed42315a86e
12 schema:keywords ARDS patients
13 ARDS therapy
14 FiO2
15 abnormal inflammatory response
16 acute phase
17 adequate arterial oxygenation
18 adequate gas exchange
19 adult respiratory distress syndrome
20 airway pressure
21 arterial blood gases
22 arterial oxygenation
23 barotrauma
24 blood gases
25 central role
26 concept
27 consequences
28 conventional mode
29 convincing data
30 data
31 distress syndrome
32 effective ventilation
33 exchange
34 expiratory pressure
35 exposure
36 function
37 gas exchange
38 gases
39 high airway pressures
40 high pressure
41 hypercapnia
42 inevitable consequence
43 inflammatory response
44 initial abnormal inflammatory response
45 injury
46 life
47 limitations
48 lower minute ventilation
49 lung exposure
50 lung injury
51 mechanical ventilation
52 minute ventilation
53 mode
54 mode of ventilation
55 morbidity
56 mortality
57 new concept
58 new strategy
59 optimal ventilation
60 oxygen toxicity
61 oxygenation
62 patients
63 phase
64 positive-end expiratory pressure
65 pressure
66 productive life
67 pulmonary function
68 pulmonary limitations
69 reduction
70 respiratory distress syndrome
71 respiratory function
72 response
73 risk
74 role
75 serious pulmonary limitations
76 specific treatment
77 strategies
78 support
79 syndrome
80 terms
81 terms of reduction
82 therapy
83 toxicity
84 treatment
85 turn
86 types
87 ventilation
88 ventilator-induced barotrauma
89 ventilatory mode
90 ventilatory support
91 volume
92 schema:name Mechanical Ventilation should be Individually Optimized in Patients with ARDS
93 schema:pagination 81-88
94 schema:productId N5d87c5aebcdb44b4946f0f6f4c35952e
95 Ndffcf427d0554b48bdd39ae551b64e02
96 schema:publisher Ne9dda4f48383448e98225c8536d19f67
97 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050255509
98 https://doi.org/10.1007/978-3-642-79154-3_8
99 schema:sdDatePublished 2022-01-01T19:22
100 schema:sdLicense https://scigraph.springernature.com/explorer/license/
101 schema:sdPublisher N387440e3d9ec461bb92f0392f56c71fd
102 schema:url https://doi.org/10.1007/978-3-642-79154-3_8
103 sgo:license sg:explorer/license/
104 sgo:sdDataset chapters
105 rdf:type schema:Chapter
106 N387440e3d9ec461bb92f0392f56c71fd schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N3a4947d7e8554ba5bd7df6d08efcb8c9 rdf:first sg:person.0656355071.53
109 rdf:rest rdf:nil
110 N3c2ddad80117466db7b4cef359806d1a rdf:first N4c786a4ff9a84bfbb42565b426cd187e
111 rdf:rest rdf:nil
112 N4c786a4ff9a84bfbb42565b426cd187e schema:familyName Vincent
113 schema:givenName Jean-Louis
114 rdf:type schema:Person
115 N5d87c5aebcdb44b4946f0f6f4c35952e schema:name dimensions_id
116 schema:value pub.1050255509
117 rdf:type schema:PropertyValue
118 Na1d58fff9aae497b9b3c6ed42315a86e schema:isbn 978-3-540-58256-4
119 978-3-642-79154-3
120 schema:name Yearbook of Intensive Care and Emergency Medicine
121 rdf:type schema:Book
122 Ncff4ebfe141e4e45a526d4b5b04e4c57 rdf:first sg:person.0737311472.48
123 rdf:rest N3a4947d7e8554ba5bd7df6d08efcb8c9
124 Ndffcf427d0554b48bdd39ae551b64e02 schema:name doi
125 schema:value 10.1007/978-3-642-79154-3_8
126 rdf:type schema:PropertyValue
127 Ne9dda4f48383448e98225c8536d19f67 schema:name Springer Nature
128 rdf:type schema:Organisation
129 Nea94ae528c1f41b3a9436206ac4a2cf1 rdf:first sg:person.0741664152.85
130 rdf:rest Ncff4ebfe141e4e45a526d4b5b04e4c57
131 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
132 schema:name Medical and Health Sciences
133 rdf:type schema:DefinedTerm
134 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
135 schema:name Cardiorespiratory Medicine and Haematology
136 rdf:type schema:DefinedTerm
137 sg:person.0656355071.53 schema:familyName Dall’ava-Santucci
138 schema:givenName J.
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656355071.53
140 rdf:type schema:Person
141 sg:person.0737311472.48 schema:familyName Dhainaut
142 schema:givenName J. F.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737311472.48
144 rdf:type schema:Person
145 sg:person.0741664152.85 schema:familyName Brunet
146 schema:givenName F.
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741664152.85
148 rdf:type schema:Person
 




Preview window. Press ESC to close (or click here)


...