A Diversity of Elements in the Protein Kinase C Signal Transduction Pathway View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1991

AUTHORS

P. J. Parker

ABSTRACT

Historically the discovery of this signalling system draws upon the convergence of two areas of research. The first was directed at the phenomenon of agonist induced inositol lipid turnover (reviewed in (Hokin, 1985)); the second was directed at the discovery and characterization of protein kinases with signalling potential, which lead to the identification of a calcium and phospholipid-dependent protein kinase termed protein kinase C (PKC) (see (Nishizuka, 1986; Nishizuka, 1988)). The critical link between these fields is the now established second messenger diacyglycerol (DAG) which is produced during agonist stimulated inositol lipid hydrolysis (by an inositol lipid-specific phospholipase C — Ptdlns- PLC) and is itself responsible for the activation of PKC (figure 1). The inositol 1,4,5 trisphosphate head group which is concurrently produced on degradation of Ptdlns 4,5 bisphosphate also serves a second messenger role in the release of Ca2+ from intracellular stores (Streb et. al., 1983). That DAG leads to PKC activation in vivo is evidenced by a variety of reports that short chain membrane permeable DAGs can activate PKC in intact cells as judged by the phosphorylation of particular proteins (e.g. (Kawahara et. al., 1980)). Furthermore such proteins can become phosphorylated in response to agonists that stimulate Ptdlns breakdown providing evidence for a causal role in the events of agonist induced cellular responses. More... »

PAGES

167-177

Book

TITLE

Cellular Regulation by Protein Phosphorylation

ISBN

978-3-642-75144-8
978-3-642-75142-4

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-75142-4_21

DOI

http://dx.doi.org/10.1007/978-3-642-75142-4_21

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038655494


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Protein Phosphorylation Laboratory, Imperial Cancer Research Fund, 44 Lincoln\u2019s Inn Fields, London, WC2A 3PX, England"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Parker", 
        "givenName": "P. J.", 
        "id": "sg:person.01111564441.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111564441.81"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.86.9.3099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001266480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(79)91197-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003188531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(89)80160-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006566134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bi.54.070185.001225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012020337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-291x(80)80169-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013637442"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.87.21.8622", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015617085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1990.tb19431.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028525847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.86.5.1568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029825633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1990.tb19472.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031112170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(89)90048-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036180395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.84.13.4418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036867400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-4157(85)90009-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039783225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-4157(85)90009-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039783225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/334661a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040491061", 
          "https://doi.org/10.1038/334661a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1988.tb13991.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041206967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4889(91)90177-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041929455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4889(91)90177-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041929455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1989.tb14809.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042521739"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/306067a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045175878", 
          "https://doi.org/10.1038/306067a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(90)80831-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046197121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.86.13.4868", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051428882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0303-7207(89)90159-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052228232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0303-7207(89)90159-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052228232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2457254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062538427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2541501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062543191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3014651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062582855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078438055", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078771994", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078998880", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079020581", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079323687", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079586993", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079592449", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1991", 
    "datePublishedReg": "1991-01-01", 
    "description": "Historically the discovery of this signalling system draws upon the convergence of two areas of research. The first was directed at the phenomenon of agonist induced inositol lipid turnover (reviewed in (Hokin, 1985)); the second was directed at the discovery and characterization of protein kinases with signalling potential, which lead to the identification of a calcium and phospholipid-dependent protein kinase termed protein kinase C (PKC) (see (Nishizuka, 1986; Nishizuka, 1988)). The critical link between these fields is the now established second messenger diacyglycerol (DAG) which is produced during agonist stimulated inositol lipid hydrolysis (by an inositol lipid-specific phospholipase C \u2014 Ptdlns- PLC) and is itself responsible for the activation of PKC (figure 1). The inositol 1,4,5 trisphosphate head group which is concurrently produced on degradation of Ptdlns 4,5 bisphosphate also serves a second messenger role in the release of Ca2+ from intracellular stores (Streb et. al., 1983). That DAG leads to PKC activation in vivo is evidenced by a variety of reports that short chain membrane permeable DAGs can activate PKC in intact cells as judged by the phosphorylation of particular proteins (e.g. (Kawahara et. al., 1980)). Furthermore such proteins can become phosphorylated in response to agonists that stimulate Ptdlns breakdown providing evidence for a causal role in the events of agonist induced cellular responses.", 
    "editor": [
      {
        "familyName": "Heilmeyer", 
        "givenName": "Ludwig M. G.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-642-75142-4_21", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-642-75144-8", 
        "978-3-642-75142-4"
      ], 
      "name": "Cellular Regulation by Protein Phosphorylation", 
      "type": "Book"
    }, 
    "name": "A Diversity of Elements in the Protein Kinase C Signal Transduction Pathway", 
    "pagination": "167-177", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-642-75142-4_21"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b8232f54c273084aeab4ffd8a98ddefef9b70b3309de805a4de89909eccbfd93"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1038655494"
        ]
      }
    ], 
    "publisher": {
      "location": "Berlin, Heidelberg", 
      "name": "Springer Berlin Heidelberg", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-642-75142-4_21", 
      "https://app.dimensions.ai/details/publication/pub.1038655494"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T19:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000267.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-3-642-75142-4_21"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-75142-4_21'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-75142-4_21'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-75142-4_21'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-75142-4_21'


 

This table displays all metadata directly associated to this object as RDF triples.

150 TRIPLES      23 PREDICATES      57 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-642-75142-4_21 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N3c69c98eadfa48efb573e6c596279ca2
4 schema:citation sg:pub.10.1038/306067a0
5 sg:pub.10.1038/334661a0
6 https://app.dimensions.ai/details/publication/pub.1078438055
7 https://app.dimensions.ai/details/publication/pub.1078771994
8 https://app.dimensions.ai/details/publication/pub.1078998880
9 https://app.dimensions.ai/details/publication/pub.1079020581
10 https://app.dimensions.ai/details/publication/pub.1079323687
11 https://app.dimensions.ai/details/publication/pub.1079586993
12 https://app.dimensions.ai/details/publication/pub.1079592449
13 https://doi.org/10.1016/0006-291x(79)91197-5
14 https://doi.org/10.1016/0014-5793(89)80160-7
15 https://doi.org/10.1016/0014-5793(90)80831-3
16 https://doi.org/10.1016/0092-8674(89)90048-2
17 https://doi.org/10.1016/0167-4889(91)90177-y
18 https://doi.org/10.1016/0303-7207(89)90159-7
19 https://doi.org/10.1016/0304-4157(85)90009-7
20 https://doi.org/10.1016/s0006-291x(80)80169-0
21 https://doi.org/10.1073/pnas.84.13.4418
22 https://doi.org/10.1073/pnas.86.13.4868
23 https://doi.org/10.1073/pnas.86.5.1568
24 https://doi.org/10.1073/pnas.86.9.3099
25 https://doi.org/10.1073/pnas.87.21.8622
26 https://doi.org/10.1111/j.1432-1033.1988.tb13991.x
27 https://doi.org/10.1111/j.1432-1033.1989.tb14809.x
28 https://doi.org/10.1111/j.1432-1033.1990.tb19431.x
29 https://doi.org/10.1111/j.1432-1033.1990.tb19472.x
30 https://doi.org/10.1126/science.2457254
31 https://doi.org/10.1126/science.2541501
32 https://doi.org/10.1126/science.3014651
33 https://doi.org/10.1146/annurev.bi.54.070185.001225
34 schema:datePublished 1991
35 schema:datePublishedReg 1991-01-01
36 schema:description Historically the discovery of this signalling system draws upon the convergence of two areas of research. The first was directed at the phenomenon of agonist induced inositol lipid turnover (reviewed in (Hokin, 1985)); the second was directed at the discovery and characterization of protein kinases with signalling potential, which lead to the identification of a calcium and phospholipid-dependent protein kinase termed protein kinase C (PKC) (see (Nishizuka, 1986; Nishizuka, 1988)). The critical link between these fields is the now established second messenger diacyglycerol (DAG) which is produced during agonist stimulated inositol lipid hydrolysis (by an inositol lipid-specific phospholipase C — Ptdlns- PLC) and is itself responsible for the activation of PKC (figure 1). The inositol 1,4,5 trisphosphate head group which is concurrently produced on degradation of Ptdlns 4,5 bisphosphate also serves a second messenger role in the release of Ca2+ from intracellular stores (Streb et. al., 1983). That DAG leads to PKC activation in vivo is evidenced by a variety of reports that short chain membrane permeable DAGs can activate PKC in intact cells as judged by the phosphorylation of particular proteins (e.g. (Kawahara et. al., 1980)). Furthermore such proteins can become phosphorylated in response to agonists that stimulate Ptdlns breakdown providing evidence for a causal role in the events of agonist induced cellular responses.
37 schema:editor N2eddbf411d774d40a537b8c3c666e1c2
38 schema:genre chapter
39 schema:inLanguage en
40 schema:isAccessibleForFree false
41 schema:isPartOf N4e424920dec44dedbf89b9d875f56ab6
42 schema:name A Diversity of Elements in the Protein Kinase C Signal Transduction Pathway
43 schema:pagination 167-177
44 schema:productId N19d0b2ed5e064378b3c8b5b1d8fff85f
45 N292cdc2d25704ea180bd12f9cef86975
46 N6971b216b36749d9b8fcff1efb03bd87
47 schema:publisher N74478fe5b1044575991f4bc3c6732fdc
48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038655494
49 https://doi.org/10.1007/978-3-642-75142-4_21
50 schema:sdDatePublished 2019-04-15T19:11
51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
52 schema:sdPublisher N02dd95fab5ec49cdb6c83ab04c93da2a
53 schema:url http://link.springer.com/10.1007/978-3-642-75142-4_21
54 sgo:license sg:explorer/license/
55 sgo:sdDataset chapters
56 rdf:type schema:Chapter
57 N02dd95fab5ec49cdb6c83ab04c93da2a schema:name Springer Nature - SN SciGraph project
58 rdf:type schema:Organization
59 N19d0b2ed5e064378b3c8b5b1d8fff85f schema:name dimensions_id
60 schema:value pub.1038655494
61 rdf:type schema:PropertyValue
62 N292cdc2d25704ea180bd12f9cef86975 schema:name readcube_id
63 schema:value b8232f54c273084aeab4ffd8a98ddefef9b70b3309de805a4de89909eccbfd93
64 rdf:type schema:PropertyValue
65 N2eddbf411d774d40a537b8c3c666e1c2 rdf:first Nd4294172a166469e9d1e5fec623f3674
66 rdf:rest rdf:nil
67 N3c69c98eadfa48efb573e6c596279ca2 rdf:first sg:person.01111564441.81
68 rdf:rest rdf:nil
69 N4e424920dec44dedbf89b9d875f56ab6 schema:isbn 978-3-642-75142-4
70 978-3-642-75144-8
71 schema:name Cellular Regulation by Protein Phosphorylation
72 rdf:type schema:Book
73 N6971b216b36749d9b8fcff1efb03bd87 schema:name doi
74 schema:value 10.1007/978-3-642-75142-4_21
75 rdf:type schema:PropertyValue
76 N74478fe5b1044575991f4bc3c6732fdc schema:location Berlin, Heidelberg
77 schema:name Springer Berlin Heidelberg
78 rdf:type schema:Organisation
79 Nd4294172a166469e9d1e5fec623f3674 schema:familyName Heilmeyer
80 schema:givenName Ludwig M. G.
81 rdf:type schema:Person
82 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
83 schema:name Biological Sciences
84 rdf:type schema:DefinedTerm
85 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
86 schema:name Biochemistry and Cell Biology
87 rdf:type schema:DefinedTerm
88 sg:person.01111564441.81 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
89 schema:familyName Parker
90 schema:givenName P. J.
91 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111564441.81
92 rdf:type schema:Person
93 sg:pub.10.1038/306067a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045175878
94 https://doi.org/10.1038/306067a0
95 rdf:type schema:CreativeWork
96 sg:pub.10.1038/334661a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040491061
97 https://doi.org/10.1038/334661a0
98 rdf:type schema:CreativeWork
99 https://app.dimensions.ai/details/publication/pub.1078438055 schema:CreativeWork
100 https://app.dimensions.ai/details/publication/pub.1078771994 schema:CreativeWork
101 https://app.dimensions.ai/details/publication/pub.1078998880 schema:CreativeWork
102 https://app.dimensions.ai/details/publication/pub.1079020581 schema:CreativeWork
103 https://app.dimensions.ai/details/publication/pub.1079323687 schema:CreativeWork
104 https://app.dimensions.ai/details/publication/pub.1079586993 schema:CreativeWork
105 https://app.dimensions.ai/details/publication/pub.1079592449 schema:CreativeWork
106 https://doi.org/10.1016/0006-291x(79)91197-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003188531
107 rdf:type schema:CreativeWork
108 https://doi.org/10.1016/0014-5793(89)80160-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006566134
109 rdf:type schema:CreativeWork
110 https://doi.org/10.1016/0014-5793(90)80831-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046197121
111 rdf:type schema:CreativeWork
112 https://doi.org/10.1016/0092-8674(89)90048-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036180395
113 rdf:type schema:CreativeWork
114 https://doi.org/10.1016/0167-4889(91)90177-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1041929455
115 rdf:type schema:CreativeWork
116 https://doi.org/10.1016/0303-7207(89)90159-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052228232
117 rdf:type schema:CreativeWork
118 https://doi.org/10.1016/0304-4157(85)90009-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039783225
119 rdf:type schema:CreativeWork
120 https://doi.org/10.1016/s0006-291x(80)80169-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013637442
121 rdf:type schema:CreativeWork
122 https://doi.org/10.1073/pnas.84.13.4418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036867400
123 rdf:type schema:CreativeWork
124 https://doi.org/10.1073/pnas.86.13.4868 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051428882
125 rdf:type schema:CreativeWork
126 https://doi.org/10.1073/pnas.86.5.1568 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029825633
127 rdf:type schema:CreativeWork
128 https://doi.org/10.1073/pnas.86.9.3099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001266480
129 rdf:type schema:CreativeWork
130 https://doi.org/10.1073/pnas.87.21.8622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015617085
131 rdf:type schema:CreativeWork
132 https://doi.org/10.1111/j.1432-1033.1988.tb13991.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041206967
133 rdf:type schema:CreativeWork
134 https://doi.org/10.1111/j.1432-1033.1989.tb14809.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042521739
135 rdf:type schema:CreativeWork
136 https://doi.org/10.1111/j.1432-1033.1990.tb19431.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028525847
137 rdf:type schema:CreativeWork
138 https://doi.org/10.1111/j.1432-1033.1990.tb19472.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031112170
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1126/science.2457254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062538427
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1126/science.2541501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062543191
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1126/science.3014651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062582855
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1146/annurev.bi.54.070185.001225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012020337
147 rdf:type schema:CreativeWork
148 https://www.grid.ac/institutes/grid.11485.39 schema:alternateName Cancer Research UK
149 schema:name Protein Phosphorylation Laboratory, Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London, WC2A 3PX, England
150 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...