Catheter Biopsy Assessed Cardiomyopathic and Postmyocarditic Changes in Cases with Atrioventricular or Intraventricular Conduction Disturbance View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1983

AUTHORS

Motonari Hasumi , Morie Sekiguchi , Shinichiro Morimoto , Machiko Take , Michiaki Hiroe , Satoshi Ohnishi , Hiroshi Kasanuki , Koshichiro Hirosawa

ABSTRACT

To determine the cause of A-V block or intraventricular conduction disturbance (IVCD) at the clinical level is usually difficult. Our experience with endomyocardial biopsy which exceeds 1300 cases has revealed that biopsy is useful in diagnosing and assessing myocardial disease. A serial biopsy study in 10 cases with acute viral myocarditis has enabled us to define the histopathological criteria of postmyocarditic change (PMC). Eighty-eight cases with A-V block and 51 cases with IVCD underwent biopsy in order to better understand the nature and incidence of myocardial change. Those cases where the ECG abnormalities were the most pertinent to the clinical findings were selected for this study. Accordingly, 91 of 139 cases were idiopathic. Diagnosis of cardiac sarcoidosis in 2 cases and of cardiac amyloidosis in I case were made with the biopsy. Twenty-three of 91 idiopathic cases (25%) showed significant myocardial pathology. In 38 of 91 idiopathic cases (42%), PMC was detected. His-bundle electrogram revealed that in cases with A-V block, H-V prolongation was correlated with the significant pathology. Most of the cases were not classified into either dilated or hypertrophic cardiomyopathy but were classified according to our proposed term: “Arrhythmia-conduction disturbance type of cardiomyopathy”. A long-term follow up of up to 13 years in 87 cases among the 139 cases revealed that the apparent heart muscle diseases such as sarcoidosis, amyloidosis, dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) were more prone to have short prognosis. It is concluded that in those cases where the A-V block or IVCD exists and when pacemaker implantation is considered, biopsy is useful in making diagnosis and also in recognizing the nature of the disease and its severity. More... »

PAGES

101-108

Book

TITLE

Cardiac Pacing

ISBN

978-3-642-72369-8
978-3-642-72367-4

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-72367-4_16

DOI

http://dx.doi.org/10.1007/978-3-642-72367-4_16

DIMENSIONS

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