Metabolic Significance and Biogenesis of Microbodies in Yeasts View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1987

AUTHORS

M. Veenhuis , W. Harder

ABSTRACT

In yeasts proliferation of microbodies (glyoxysomes/peroxisomes) is largely prescribed by the growth environment and due to the fact that the organelles harbour essential enzymic functions required for the metabolism of the carbon and/or nitrogen source. Presently activities of more than 20 different enzymes have been shown to reside in yeast microbodies namely catalase, several H202-producing oxidases and enzymes involved in 8-oxidation, glyoxylate cycle enzymes, dehydrogenases, an amino transferase and a transketolase. The functioning of these organelles often requires extensive metabolic interactions with other cell compartments such as mitochondria, microsomes or the cyrosol. Yeast microbodies have been shown to be acidic in nature with an internal pH of 5.8 – 6.0 whereas the cytosolic pH is approximately 7.1. This electrochemical proton gradient — generated by a membrane bound H+-ATPase — may play an important role in different transport processes across the peroxisomal membrane including uptake of matrix proteins and transport of low molecular weight compounds such as substrates and/or metabolic intermediates. More... »

PAGES

436-458

References to SciGraph publications

Book

TITLE

Peroxisomes in Biology and Medicine

ISBN

978-3-642-71327-9
978-3-642-71325-5

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-71325-5_47

DOI

http://dx.doi.org/10.1007/978-3-642-71325-5_47

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022075146


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