Ciclosporin (CyA) in Primary Biliary Cirrhosis (PBC): A Multicentre, Double-blind, Placebo-controlled Long-term Therapeutic Study. The Study Design View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1985

AUTHORS

N. Tygstrup , L. Ranek , E. Juhl , S. Keiding , E. Christensen , R. Williams , J. Neuberger , J. Rodes

ABSTRACT

Primary biliary cirrhosis (PBC) is a chronic inflammatory disease involving the intrahepatic bile ducts and progressing to cirrhosis, liver failure and variceal hemorrhage. Sjögren’s syndrome and pancreatic hyposecretion occur in up to 70% of patients with PBC, thus accounting for the “dry gland syndrome”. The incidence of PBC is approximately 50 per million population [5] and PBC is more common in females aged 40–60 years. The mean duration of survival of symptomatic patients is approximately 11.9 years [2], but symptomfree patients appear to have a similar life expectancy to age-matched and sex-matched controls from the general population of the USA [3]. More... »

PAGES

182-184

References to SciGraph publications

  • 1980-02. Suppressor cell activity in primary biliary cirrhosis in DIGESTIVE DISEASES AND SCIENCES
  • Book

    TITLE

    Ciclosporin in Autoimmune Diseases

    ISBN

    978-3-642-70609-7
    978-3-642-70607-3

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-642-70607-3_32

    DOI

    http://dx.doi.org/10.1007/978-3-642-70607-3_32

    DIMENSIONS

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