Defect of Ferritin Secretion in HLA-A3 Subjects and in Idiopathic Hemochromatosis View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1984

AUTHORS

B. Martins da Silva , R. Fauchet , B. Genetet , L. Le Mignon , M. Simon , M. de Sousa

ABSTRACT

We previously described an impairment of ferritin secretion in peripheral blood mononuclear cells from normal HLA-A3 subjects following stimulation in vitro with phytohemagglutinin (PHA) and concanavalin A (Con A) with or without addition of ferric citrate [1–3]. We now re-examine the association of ferritin secretion with HLA-A phenotype in a population of controls and idiopathic hemochromatosis (IH) patients in Brittany, the region where family studies first documented a linkage disequilibrium of the HLA-A3 antigen in IH [4]. More... »

PAGES

661-661

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-69770-8_255

DOI

http://dx.doi.org/10.1007/978-3-642-69770-8_255

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022478967


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