Analytical and Numerical Approaches for Optimization Design of MEMS Based SU-8 Microneedles View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

Nhut Tran-Minh , Hoa Le-Thanh , Frank Karlsen

ABSTRACT

This paper addresses the optimization design of the MEMS based SU-8 microneedles for blood extraction by studying the effects of axial and transverse force on SU-8 microneedles during skin insertion in both analytical and numerical points of view. The critical buckling load and maximum bending force that the needle can withstand are 4.486N and 0.123N for 1200μm length (300μm x 300μm) needle, respectively. As the results of numerical simulation, the maximum stress 1.0719MPa, which occurs at the tip, is smaller than 34MPa of yield strength of SU-8. The bending test is also proved by applying the force of 0.1N on the tip of needle, resulting 33.8MPa of maximum stress which is comparable to 34MPa of yield strength of SU-8. Based on these results, the numerical simulation also proves that the needle with our design is strong enough for inserting into human skin. More... »

PAGES

105-114

References to SciGraph publications

Book

TITLE

Biomedical Informatics and Technology

ISBN

978-3-642-54120-9
978-3-642-54121-6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-54121-6_9

DOI

http://dx.doi.org/10.1007/978-3-642-54121-6_9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039655498


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Vestfold University College", 
          "id": "https://www.grid.ac/institutes/grid.412820.d", 
          "name": [
            "Vestfold University College, Postboks 2243, N-3103\u00a0Tonsberg, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tran-Minh", 
        "givenName": "Nhut", 
        "id": "sg:person.01246267071.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246267071.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vestfold University College", 
          "id": "https://www.grid.ac/institutes/grid.412820.d", 
          "name": [
            "Vestfold University College, Postboks 2243, N-3103\u00a0Tonsberg, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le-Thanh", 
        "givenName": "Hoa", 
        "id": "sg:person.015530724316.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015530724316.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vestfold University College", 
          "id": "https://www.grid.ac/institutes/grid.412820.d", 
          "name": [
            "Vestfold University College, Postboks 2243, N-3103\u00a0Tonsberg, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karlsen", 
        "givenName": "Frank", 
        "id": "sg:person.0615237177.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615237177.16"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1088/0960-1317/16/5/012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001050099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1088/0960-1317/16/5/012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001050099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.07-0066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004538814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.2331316100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004630788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10544-012-9683-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010623080", 
          "https://doi.org/10.1007/s10544-012-9683-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jconrel.2006.10.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013155071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1013607400040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020760563", 
          "https://doi.org/10.1023/a:1013607400040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.sna.2005.05.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030631949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.sna.2005.05.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030631949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10255842.2010.497144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038305333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jbiomech.2003.12.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039507975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cherd.2008.06.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044327605"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014", 
    "datePublishedReg": "2014-01-01", 
    "description": "This paper addresses the optimization design of the MEMS based SU-8 microneedles for blood extraction by studying the effects of axial and transverse force on SU-8 microneedles during skin insertion in both analytical and numerical points of view. The critical buckling load and maximum bending force that the needle can withstand are 4.486N and 0.123N for 1200\u03bcm length (300\u03bcm x 300\u03bcm) needle, respectively. As the results of numerical simulation, the maximum stress 1.0719MPa, which occurs at the tip, is smaller than 34MPa of yield strength of SU-8. The bending test is also proved by applying the force of 0.1N on the tip of needle, resulting 33.8MPa of maximum stress which is comparable to 34MPa of yield strength of SU-8. Based on these results, the numerical simulation also proves that the needle with our design is strong enough for inserting into human skin.", 
    "editor": [
      {
        "familyName": "Pham", 
        "givenName": "Tuan D.", 
        "type": "Person"
      }, 
      {
        "familyName": "Ichikawa", 
        "givenName": "Kazuhisha", 
        "type": "Person"
      }, 
      {
        "familyName": "Oyama-Higa", 
        "givenName": "Mayumi", 
        "type": "Person"
      }, 
      {
        "familyName": "Coomans", 
        "givenName": "Danny", 
        "type": "Person"
      }, 
      {
        "familyName": "Jiang", 
        "givenName": "Xiaoyi", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-642-54121-6_9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-642-54120-9", 
        "978-3-642-54121-6"
      ], 
      "name": "Biomedical Informatics and Technology", 
      "type": "Book"
    }, 
    "name": "Analytical and Numerical Approaches for Optimization Design of MEMS Based SU-8 Microneedles", 
    "pagination": "105-114", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-642-54121-6_9"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "bce6a6fddd7f3bff04ed3d3ab295ed671a69af922198d561cad175617543117c"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039655498"
        ]
      }
    ], 
    "publisher": {
      "location": "Berlin, Heidelberg", 
      "name": "Springer Berlin Heidelberg", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-642-54121-6_9", 
      "https://app.dimensions.ai/details/publication/pub.1039655498"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T22:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000267.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-3-642-54121-6_9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-54121-6_9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-54121-6_9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-54121-6_9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-642-54121-6_9'


 

This table displays all metadata directly associated to this object as RDF triples.

131 TRIPLES      23 PREDICATES      37 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-642-54121-6_9 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Ne656e112579841c7b029e04e69534eb5
4 schema:citation sg:pub.10.1007/s10544-012-9683-2
5 sg:pub.10.1023/a:1013607400040
6 https://doi.org/10.1016/j.cherd.2008.06.002
7 https://doi.org/10.1016/j.jbiomech.2003.12.010
8 https://doi.org/10.1016/j.jconrel.2006.10.017
9 https://doi.org/10.1016/j.sna.2005.05.017
10 https://doi.org/10.1073/pnas.2331316100
11 https://doi.org/10.1080/10255842.2010.497144
12 https://doi.org/10.1088/0960-1317/16/5/012
13 https://doi.org/10.1167/iovs.07-0066
14 schema:datePublished 2014
15 schema:datePublishedReg 2014-01-01
16 schema:description This paper addresses the optimization design of the MEMS based SU-8 microneedles for blood extraction by studying the effects of axial and transverse force on SU-8 microneedles during skin insertion in both analytical and numerical points of view. The critical buckling load and maximum bending force that the needle can withstand are 4.486N and 0.123N for 1200μm length (300μm x 300μm) needle, respectively. As the results of numerical simulation, the maximum stress 1.0719MPa, which occurs at the tip, is smaller than 34MPa of yield strength of SU-8. The bending test is also proved by applying the force of 0.1N on the tip of needle, resulting 33.8MPa of maximum stress which is comparable to 34MPa of yield strength of SU-8. Based on these results, the numerical simulation also proves that the needle with our design is strong enough for inserting into human skin.
17 schema:editor N71dedcafd31a4a6bbc455dd8a025f22b
18 schema:genre chapter
19 schema:inLanguage en
20 schema:isAccessibleForFree false
21 schema:isPartOf N868032f66afd4668a186e6fb1b4019f8
22 schema:name Analytical and Numerical Approaches for Optimization Design of MEMS Based SU-8 Microneedles
23 schema:pagination 105-114
24 schema:productId N1972e2bca57d4bec98262046b683304a
25 N1e8d26e5722d490393498918a6ad23a8
26 N7d36610dcb8e473788bc2f56505f0cc2
27 schema:publisher N92a2035da3bc4f4b8a571aa8761fc7c8
28 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039655498
29 https://doi.org/10.1007/978-3-642-54121-6_9
30 schema:sdDatePublished 2019-04-15T22:00
31 schema:sdLicense https://scigraph.springernature.com/explorer/license/
32 schema:sdPublisher N8d3cbab771974e18a5a9ff413da3e521
33 schema:url http://link.springer.com/10.1007/978-3-642-54121-6_9
34 sgo:license sg:explorer/license/
35 sgo:sdDataset chapters
36 rdf:type schema:Chapter
37 N00ca653c9d92478399f7a549a418301c schema:familyName Coomans
38 schema:givenName Danny
39 rdf:type schema:Person
40 N09aac47e1a7b438790a8279f162a2bc9 rdf:first Na8dd4f3add0646f08724e42bd08cfea1
41 rdf:rest N526e0ec15d404feba12fabc194184b68
42 N1972e2bca57d4bec98262046b683304a schema:name doi
43 schema:value 10.1007/978-3-642-54121-6_9
44 rdf:type schema:PropertyValue
45 N1e8d26e5722d490393498918a6ad23a8 schema:name readcube_id
46 schema:value bce6a6fddd7f3bff04ed3d3ab295ed671a69af922198d561cad175617543117c
47 rdf:type schema:PropertyValue
48 N218460ed1a9a410abee1fbdb2cf5a216 rdf:first N9376f27f97ef4560813fe81180f85427
49 rdf:rest rdf:nil
50 N4ca121601bd14444b1f37f97aeeef93d schema:familyName Pham
51 schema:givenName Tuan D.
52 rdf:type schema:Person
53 N526e0ec15d404feba12fabc194184b68 rdf:first N00ca653c9d92478399f7a549a418301c
54 rdf:rest N218460ed1a9a410abee1fbdb2cf5a216
55 N71dedcafd31a4a6bbc455dd8a025f22b rdf:first N4ca121601bd14444b1f37f97aeeef93d
56 rdf:rest N7c3dc0d064db4513882318c379609272
57 N7c3dc0d064db4513882318c379609272 rdf:first Nd7df330d65af44c9a4694a8834f87085
58 rdf:rest N09aac47e1a7b438790a8279f162a2bc9
59 N7d36610dcb8e473788bc2f56505f0cc2 schema:name dimensions_id
60 schema:value pub.1039655498
61 rdf:type schema:PropertyValue
62 N868032f66afd4668a186e6fb1b4019f8 schema:isbn 978-3-642-54120-9
63 978-3-642-54121-6
64 schema:name Biomedical Informatics and Technology
65 rdf:type schema:Book
66 N8d3cbab771974e18a5a9ff413da3e521 schema:name Springer Nature - SN SciGraph project
67 rdf:type schema:Organization
68 N92a2035da3bc4f4b8a571aa8761fc7c8 schema:location Berlin, Heidelberg
69 schema:name Springer Berlin Heidelberg
70 rdf:type schema:Organisation
71 N9376f27f97ef4560813fe81180f85427 schema:familyName Jiang
72 schema:givenName Xiaoyi
73 rdf:type schema:Person
74 Na8dd4f3add0646f08724e42bd08cfea1 schema:familyName Oyama-Higa
75 schema:givenName Mayumi
76 rdf:type schema:Person
77 Nac9193e1966e4cdab2af4ae8cf07f88e rdf:first sg:person.015530724316.81
78 rdf:rest Nf64af243fd3047ca90fe7f9bdbfc327a
79 Nd7df330d65af44c9a4694a8834f87085 schema:familyName Ichikawa
80 schema:givenName Kazuhisha
81 rdf:type schema:Person
82 Ne656e112579841c7b029e04e69534eb5 rdf:first sg:person.01246267071.75
83 rdf:rest Nac9193e1966e4cdab2af4ae8cf07f88e
84 Nf64af243fd3047ca90fe7f9bdbfc327a rdf:first sg:person.0615237177.16
85 rdf:rest rdf:nil
86 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
87 schema:name Medical and Health Sciences
88 rdf:type schema:DefinedTerm
89 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
90 schema:name Clinical Sciences
91 rdf:type schema:DefinedTerm
92 sg:person.01246267071.75 schema:affiliation https://www.grid.ac/institutes/grid.412820.d
93 schema:familyName Tran-Minh
94 schema:givenName Nhut
95 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246267071.75
96 rdf:type schema:Person
97 sg:person.015530724316.81 schema:affiliation https://www.grid.ac/institutes/grid.412820.d
98 schema:familyName Le-Thanh
99 schema:givenName Hoa
100 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015530724316.81
101 rdf:type schema:Person
102 sg:person.0615237177.16 schema:affiliation https://www.grid.ac/institutes/grid.412820.d
103 schema:familyName Karlsen
104 schema:givenName Frank
105 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615237177.16
106 rdf:type schema:Person
107 sg:pub.10.1007/s10544-012-9683-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010623080
108 https://doi.org/10.1007/s10544-012-9683-2
109 rdf:type schema:CreativeWork
110 sg:pub.10.1023/a:1013607400040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020760563
111 https://doi.org/10.1023/a:1013607400040
112 rdf:type schema:CreativeWork
113 https://doi.org/10.1016/j.cherd.2008.06.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044327605
114 rdf:type schema:CreativeWork
115 https://doi.org/10.1016/j.jbiomech.2003.12.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039507975
116 rdf:type schema:CreativeWork
117 https://doi.org/10.1016/j.jconrel.2006.10.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013155071
118 rdf:type schema:CreativeWork
119 https://doi.org/10.1016/j.sna.2005.05.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030631949
120 rdf:type schema:CreativeWork
121 https://doi.org/10.1073/pnas.2331316100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004630788
122 rdf:type schema:CreativeWork
123 https://doi.org/10.1080/10255842.2010.497144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038305333
124 rdf:type schema:CreativeWork
125 https://doi.org/10.1088/0960-1317/16/5/012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001050099
126 rdf:type schema:CreativeWork
127 https://doi.org/10.1167/iovs.07-0066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004538814
128 rdf:type schema:CreativeWork
129 https://www.grid.ac/institutes/grid.412820.d schema:alternateName Vestfold University College
130 schema:name Vestfold University College, Postboks 2243, N-3103 Tonsberg, Norway
131 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...