Intra-Operative Ex-Situ and In-Situ Optical Biopsy Using Light-CT View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Martine Antoine , Brigitte Sigal , Fabrice Harms , Anne Latrive , Adriano Burcheri , Osnath Assayag , Bertrand de Poly , Sylvain Gigan , A. Claude Boccara

ABSTRACT

The field of digital pathology is evolving very quickly: there is an increasing implication of laboratories and imaging companies in the biomedical field of histology. For our part we propose a digital imaging tool based on optical interferometry with short coherence length light sources (OCT). This instrument provides, without preparation or contrast agents , virtual sections of biological tissues with a field of view (1cm 2) and spatial resolution (approximately 1 micron in 3-D) suitable for histology. We show the relevance of this approach by comparing our images obtained in minutes during surgery with histological sections obtained after a few days. In these studies we worked on fixed tissue, fresh tissue in vivo or ex vivo. Finally, an endoscopic probe based on the same principle has been validated ex-vivo for use inside the bodies of patients. More... »

PAGES

77-84

References to SciGraph publications

Book

TITLE

Advances in Bio-Imaging: From Physics to Signal Understanding Issues

ISBN

978-3-642-25546-5
978-3-642-25547-2

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-25547-2_7

DOI

http://dx.doi.org/10.1007/978-3-642-25547-2_7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009956811


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