A Novel Grid-Based Visualization Approach for Metabolic Networks with Advanced Focus&Context View View Full Text


Ontology type: schema:Chapter      Open Access: True


Chapter Info

DATE

2010

AUTHORS

Markus Rohrschneider , Christian Heine , André Reichenbach , Andreas Kerren , Gerik Scheuermann

ABSTRACT

The universe of biochemical reactions in metabolic pathways can be modeled as a complex network structure augmented with domain specific annotations. Based on the functional properties of the involved reactions, metabolic networks are often clustered into so-called pathways inferred from expert knowledge. To support the domain expert in the exploration and analysis process, we follow the well-known Table Lens metaphor with the possibility to select multiple foci. In this paper, we introduce a novel approach to generate an interactive layout of such a metabolic network taking its hierarchical structure into account and present methods for navigation and exploration that preserve the mental map. The layout places the network nodes on a fixed rectilinear grid and routes the edges orthogonally between the node positions. Our approach supports bundled edge routes heuristically minimizing a given cost function based on the number of bends, the number of edge crossings and the density of edges within a bundle. More... »

PAGES

268-279

Book

TITLE

Graph Drawing

ISBN

978-3-642-11804-3
978-3-642-11805-0

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-11805-0_26

DOI

http://dx.doi.org/10.1007/978-3-642-11805-0_26

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029045249


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