Prognostic Value of Wave Intensity in Patients Awaiting Heart Transplantation View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2009

AUTHORS

Henryk Siniawski , Hans B. Lehmkuhl , Michael Dandel , Yuguo Weng , Roland Hetzer

ABSTRACT

Background: Prospective comparative studies to predict the risk of hemodynamic deterioration in patients referred for transplantation were performed on the basis of standard invasive and non-invasive data and new wave intensity (WI) parameters.Methods and results: Study group 1 consisted of 150 consecutive outpatients (age 48.7±12 years; 110 men) with endstage dilative cardiomyopathy. Group 2, consisting of 11 consecutive patients (age 50±11 years; 6 men) with sinus rhythm and “true” decompensation, was used to create “critical” values of WI. There were no demographic or somatic (weight and height) differences between the groups. The follow-up period of ambulatory patients was 31±8 months. Non-invasive WI was studied in the common carotid artery. Complete invasive and noninvasive data were also recorded on the day of investigation. During follow-up 44 pts were lost: there were 15 cardiac deaths (10%), life-saving ventricular assist device implantation in 10 (6.6%) and transplantation in 19 (12.7%). For statistical purposes this group was named “events” group B (n=44). A predisposing factor for events (death, “true” decompensation and “urgent” transplantation in ambulatory patients) was low first peak (“critical” value assessed in group 2 <4100 mmHg*s3) (OR 45.6, CI 14.5-143.3, p<0.001). Less powerful predictors of the risk of deterioration were PCP, diastolic PAP and E/A mitral wave relation (p=0.05).Conclusions: The new ventricular-arterial coupling parameter 1st peak of WI can potentially be used to distinguish patients at high risk for true deterioration and death. More... »

PAGES

29-32

Book

TITLE

World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany

ISBN

978-3-642-03881-5
978-3-642-03882-2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-642-03882-2_8

DOI

http://dx.doi.org/10.1007/978-3-642-03882-2_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005576373


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