Towards Automatic Generation of 3D Models of Biological Objects Based on Serial Sections View Full Text


Ontology type: schema:Chapter      Open Access: True


Chapter Info

DATE

2008

AUTHORS

Vincent Jasper Dercksen , Cornelia Brüß , Detlev Stalling , Sabine Gubatz , Udo Seiffert , Hans-Christian Hege

ABSTRACT

We present a set of coherent methods for the nearly automatic creation of 3D geometric models from large stacks of images of histological sections. Three-dimensional surface models facilitate the visual analysis of 3D anatomy. They also form a basis for standardized anatomical atlases that allow researchers to integrate, accumulate and associate heterogeneous experimental information, like functional or gene-expression data, with spatial or even spatio-temporal reference. Models are created by performing the following steps: image stitching, slice alignment, elastic registration, image segmentation and surface reconstruction. The proposed methods are to a large extent automatic and robust against inevitably occurring imaging artifacts. The option of interactive control at most stages of the modeling process complements automatic methods. More... »

PAGES

3-25

References to SciGraph publications

Book

TITLE

Visualization in Medicine and Life Sciences

ISBN

978-3-540-72629-6
978-3-540-72630-2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-540-72630-2_1

DOI

http://dx.doi.org/10.1007/978-3-540-72630-2_1

DIMENSIONS

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