Acute Kidney Transplant Failure View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2010

AUTHORS

Ralf Schindler

ABSTRACT

The glomerular filtration rate (GFR) of the renal transplant usually averages around 40–50 ml/min. Thus, even slight decreases in GFR that may remain undetected in a healthy patient will cause a rapid increase in serum creatinine in the transplanted patient. Calcineurin inhibitors as part of immunosuppressive protocols may cause renal vasoconstriction and also interact with a variety of other drugs, thus potentially increasing their nephrotoxic potential. Acute allograft failure may occur in the context of severe infections, secondary to diarrhea and fluid loss, or as a consequence of disturbed (arterial of venous) graft perfusion. If these potential reasons have been investigated and excluded, a renal biopsy must be performed to establish the diagnosis of rejection. More... »

PAGES

439-443

Book

TITLE

Management of Acute Kidney Problems

ISBN

978-3-540-69413-7
978-3-540-69441-0

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-540-69441-0_44

DOI

http://dx.doi.org/10.1007/978-3-540-69441-0_44

DIMENSIONS

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