Near-Field Microscopy for Biomolecular Systems View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2002

AUTHORS

T. Yanagida , E. Tamiya , H. Muramatsu , P. Degenaar , Y. Ishii , Y. Sako , K. Saito , S. Ohta-Iino , S. Ogawa , G. Marriott , A. Kusumi , H. Tatsumi

ABSTRACT

Direct visualization of functioning biomolecular systems (cells and subcellular organelles and molecules) has been one of the greatest dreams of biologists. Conventional techniques for high-resolution imaging of biological materials use high-energy electrons (e.g., electron microscope) or X rays (e.g., X-ray microscope). Since these high energy particles or waves significantly damage biolomecular systems, direct visualization of functioning biomolecular systems has been remained difficult. The recent development of near-field optics and related technology enable us to realize this dream partially. There are two ways to use near-field optical phenomena in biological applications; one is a scanning near-field optical microscope (SNOM) and the other is a total internal reflection fluorescence microscope. Technical details of these near-field optical microscopes are mentioned elsewhere (see related chapters in this book). More... »

PAGES

191-236

Book

TITLE

Nano-Optics

ISBN

978-3-642-07527-8
978-3-540-45273-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-540-45273-7_8

DOI

http://dx.doi.org/10.1007/978-3-540-45273-7_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003516054


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