Gene3D and Understanding Proteome Evolution View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2007

AUTHORS

Juan Garcia Ranea , Corin Yeats , Russell Marsden , Christine Orengo

ABSTRACT

Gene3D is a database of protein sequence families. The families have been created through clustering the proteome sequences of over 200 species, including more than 15 eukaryotes, and totalling over 750,000 proteins (as derived from UniProt [1]). Each family is then further subclustered on the basis of sequence similarity. Using remote homologue detection methods, we have been able to assign structures – based on the CATH [2] and Pfam [3] databases – to a majority of these sequences. This allows a high resolution view of the functions and evolution of specific protein families, as well as the evolution of a species' gene content. More... »

PAGES

37-55

Book

TITLE

Structural Approaches to Sequence Evolution

ISBN

978-3-540-35305-8
978-3-540-35306-5

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-540-35306-5_2

DOI

http://dx.doi.org/10.1007/978-3-540-35306-5_2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036485843


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