Differential Gene Survival under Asymmetric Directional Mutational Pressure View Full Text


Ontology type: schema:Chapter      Open Access: True


Chapter Info

DATE

2004

AUTHORS

Paweł Mackiewicz , Małgorzata Dudkiewicz , Maria Kowalczuk , Dorota Mackiewicz , Joanna Banaszak , Natalia Polak , Kamila Smolarczyk , Aleksandra Nowicka , Mirosław R. Dudek , Stanisław Cebrat

ABSTRACT

We have simulated, using Monte Carlo methods, the survival of prokaryotic genes under directional mutational pressure. We have found that the whole pool of genes located on the leading DNA strand differs from that located on the lagging DNA strand and from the subclass of genes coding for ribosomal proteins. The best strategy for most of the non-ribosomal genes is to change the direction of the mutational pressure from time to time or to stay at their recent position. Genes coding for ribosomal proteins do not profit to such an extent from switching the directional pressure which seems to explain their extremely conserved positions on the prokaryotic chromosomes. More... »

PAGES

687-693

Book

TITLE

Computational Science - ICCS 2004

ISBN

978-3-540-22129-6
978-3-540-25944-2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-540-25944-2_89

DOI

http://dx.doi.org/10.1007/978-3-540-25944-2_89

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048004118


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