Use of a Turn Coil and Channel Above a GMR-SV Device to Observe and Measure the Properties of Deoxidized Red ... View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018-08-30

AUTHORS

Jong-Gu Choi , Su-Hee Kim , Sang-Suk Lee

ABSTRACT

A giant magnetoresistance-spin valve (GMR-SV) having highly sensitive magnetic properties was prepared with a multilayer soft ferromagnetic/non-magnetic/pinned ferromagnetic/anti-ferromagnetic iridium manganese (IrMn) top layer (NiFe/CoFe/Cu/CoFe/IrMn) structure. Micron-sized magnetic beads (MBs) with a diameter of 1 μm immersed in a solution containing 50 mg of Co-Si-OH/ml were attached to red blood cells (RBCs) having the very low magnetization of hemoglobin (HEM) to detect a deoxidized RBC combined with MBs (RBC+MBs). The RBC+MB combinations can be captured on a single-turn μ-coil that maintains a magnetic field large enough to detect the MBs attached to the RBC. When the RBC+MBs passes through a PR μ-channel with a width of 10 μm, its stopping and starting are controlled by the electrical AC input signal applied to the single-turn μ-coil. The RBC+MBs combinations captured above the μ-device of the GMR-SV change the output signal and thus, can be used for detection. This observation implies that this device can be used as a biosensor to analyze the coupling force between the HEM and the MBs for RBCs with deformed membranes passing through a narrow capillary. More... »

PAGES

345-349

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-91287-5_55

DOI

http://dx.doi.org/10.1007/978-3-319-91287-5_55

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106526122

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30178369


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