Therapeutic/Theranostic Use of Radionanomedicine View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018-05-26

AUTHORS

So Won Oh , Dong Soo Lee

ABSTRACT

Radionanomedicine is a newly emerged field of medicine extending nuclear medicine by means of nanomaterial technology and platforms. Radionanomedicine utilizes versatility of nanoparticles (NP) and avoids inherent toxic effect of NPs. This is mainly due to the fact that NPs are used in trace amounts for targeting. The therapeutic effect of radionanomedicine comes from ionizing radiation of labeled radionuclides. The core concept of radionanomedicine depends on both characteristics of radionuclides and properties of NPs. The characteristics of NPs including multifunctionality, intrinsic properties are exploited to enhance the therapeutic effect of radiolabeled NPs. In addition, various strategies have been developed to deliver sufficient amount of radiolabeled NPs, such as local administration and co-application of thermal stimuli. In an attempt to improve the therapeutic effect of radionuclides, several approaches have been investigated, such as utilizing intrinsic radioactive properties of NPs or labeling with alpha emitters. The emergence of radionanomedicine is expected to restore of the essence of nuclear medicine as well as to enhance the clinical applicability of nanomedicine. More... »

PAGES

431-442

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-67720-0_23

DOI

http://dx.doi.org/10.1007/978-3-319-67720-0_23

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1104232136


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