Ontology type: schema:Chapter
2017-09-30
AUTHORSOlivier Goureau , Christelle Monville , Antoine Chaffiol , Gregory Gauvain , Serge Picaud , Jens Duebel , José-Alain Sahel
ABSTRACTInherited and age-related retinal dystrophies, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), respectively, are a leading cause of irreversible vision loss. Various approaches aiming at restoring visual function in the blind are currently under development and evaluation: neuroprotection, gene and cell therapy, and retinal prostheses. In this review, we focus on recent advances in optogenetics and cell therapy, two therapeutic strategies that have the potential to restore vision in a broad spectrum of retinal degenerative diseases. We discuss major advantages of optogenetics and cell therapies as well as their current limitations. More... »
PAGES105-125
Retinal Prosthesis
ISBN
978-3-319-67258-8
978-3-319-67260-1
http://scigraph.springernature.com/pub.10.1007/978-3-319-67260-1_7
DOIhttp://dx.doi.org/10.1007/978-3-319-67260-1_7
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1100464972
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Neurosciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1113",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Ophthalmology and Optometry",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France",
"id": "http://www.grid.ac/institutes/grid.462844.8",
"name": [
"Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France"
],
"type": "Organization"
},
"familyName": "Goureau",
"givenName": "Olivier",
"id": "sg:person.0776412526.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776412526.00"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Universit\u00e9 Evry Val Essonne, ISTEM, Paris, France",
"id": "http://www.grid.ac/institutes/grid.8390.2",
"name": [
"Universit\u00e9 Evry Val Essonne, ISTEM, Paris, France"
],
"type": "Organization"
},
"familyName": "Monville",
"givenName": "Christelle",
"id": "sg:person.01002253626.63",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002253626.63"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France",
"id": "http://www.grid.ac/institutes/grid.462844.8",
"name": [
"Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France"
],
"type": "Organization"
},
"familyName": "Chaffiol",
"givenName": "Antoine",
"id": "sg:person.0673302301.86",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673302301.86"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France",
"id": "http://www.grid.ac/institutes/grid.462844.8",
"name": [
"Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France"
],
"type": "Organization"
},
"familyName": "Gauvain",
"givenName": "Gregory",
"id": "sg:person.01043253243.25",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043253243.25"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France",
"id": "http://www.grid.ac/institutes/grid.462844.8",
"name": [
"Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France"
],
"type": "Organization"
},
"familyName": "Picaud",
"givenName": "Serge",
"id": "sg:person.0642273724.04",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642273724.04"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France",
"id": "http://www.grid.ac/institutes/grid.462844.8",
"name": [
"Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France"
],
"type": "Organization"
},
"familyName": "Duebel",
"givenName": "Jens",
"id": "sg:person.01156573604.98",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156573604.98"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Ophthalmology, The University of Pittsburgh School of Medicine, 15213, Pittsburgh, PA, USA",
"id": "http://www.grid.ac/institutes/grid.21925.3d",
"name": [
"Institut de la Vision, Sorbonne Universit\u00e9s, UPMC Univ Paris 6, INSERM UMRS_968, CNRS UMR 7210, Paris, France",
"Centre Hospitalier National d\u2019Ophtalmologie des Quinze-Vingts, DHU Sight Restore, INSERM-DHOS CIC, Paris, France",
"Fondation Ophtalmologique Adolphe de Rothschild, Paris, France",
"Department of Ophthalmology, The University of Pittsburgh School of Medicine, 15213, Pittsburgh, PA, USA"
],
"type": "Organization"
},
"familyName": "Sahel",
"givenName": "Jos\u00e9-Alain",
"id": "sg:person.01104041722.66",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104041722.66"
],
"type": "Person"
}
],
"datePublished": "2017-09-30",
"datePublishedReg": "2017-09-30",
"description": "Inherited and age-related retinal dystrophies, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), respectively, are a leading cause of irreversible vision loss. Various approaches aiming at restoring visual function in the blind are currently under development and evaluation: neuroprotection, gene and cell therapy, and retinal prostheses. In this review, we focus on recent advances in optogenetics and cell therapy, two therapeutic strategies that have the potential to restore vision in a broad spectrum of retinal degenerative diseases. We discuss major advantages of optogenetics and cell therapies as well as their current limitations.",
"editor": [
{
"familyName": "Humayun",
"givenName": "Mark S.",
"type": "Person"
},
{
"familyName": "Olmos de Koo",
"givenName": "Lisa C.",
"type": "Person"
}
],
"genre": "chapter",
"id": "sg:pub.10.1007/978-3-319-67260-1_7",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": {
"isbn": [
"978-3-319-67258-8",
"978-3-319-67260-1"
],
"name": "Retinal Prosthesis",
"type": "Book"
},
"keywords": [
"age-related macular degeneration",
"cell therapy",
"retinitis pigmentosa",
"irreversible vision loss",
"retinal degenerative diseases",
"vision loss",
"visual function",
"macular degeneration",
"therapeutic strategies",
"retinal dystrophy",
"therapy",
"degenerative diseases",
"retinal prosthesis",
"broad spectrum",
"optogenetics",
"neuroprotection",
"degeneration",
"disease",
"pigmentosa",
"dystrophy",
"prosthesis",
"recent advances",
"cause",
"future directions",
"review",
"evaluation",
"genes",
"loss",
"current limitations",
"advances",
"function",
"development",
"strategies",
"major advantage",
"vision",
"potential",
"limitations",
"approach",
"advantages",
"direction",
"spectra"
],
"name": "Retinal Prostheses: Other Therapies and Future Directions",
"pagination": "105-125",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1100464972"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/978-3-319-67260-1_7"
]
}
],
"publisher": {
"name": "Springer Nature",
"type": "Organisation"
},
"sameAs": [
"https://doi.org/10.1007/978-3-319-67260-1_7",
"https://app.dimensions.ai/details/publication/pub.1100464972"
],
"sdDataset": "chapters",
"sdDatePublished": "2022-05-20T07:49",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/chapter/chapter_65.jsonl",
"type": "Chapter",
"url": "https://doi.org/10.1007/978-3-319-67260-1_7"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-67260-1_7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-67260-1_7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-67260-1_7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-67260-1_7'
This table displays all metadata directly associated to this object as RDF triples.
161 TRIPLES
23 PREDICATES
67 URIs
59 LITERALS
7 BLANK NODES