Purinergic Receptors: Novel Targets for Cancer Immunotherapy View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018

AUTHORS

Dipti Vijayan , Mark J. Smyth , Michele W. L. Teng

ABSTRACT

Tumor hypoxia has been a topic of immense interest to oncologists ever since its discovery by Thomlinson and Gray in 1955. In their study, the authors observed that tumors from human lung cancer patients were radio-resistant and upon histological analysis, exhibited a non-uniform distribution of oxygen. In 1977, Reinhold et al. extended on these initial findings and concluded that the architecture of blood vasculature encapsulating tumors was disordered, which subsequently led to fluctuations in oxygen levels. More... »

PAGES

115-141

References to SciGraph publications

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  • Book

    TITLE

    Oncoimmunology

    ISBN

    978-3-319-62430-3
    978-3-319-62431-0

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-319-62431-0_7

    DOI

    http://dx.doi.org/10.1007/978-3-319-62431-0_7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1099663598


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