Current Non-HSCT Treatments for SCD View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018

AUTHORS

Claire L. Anderson , Deepika S. Darbari

ABSTRACT

Sickle cell disease (SCD) is associated with many acute and chronic complications which require management with pharmacologic agents. Advances in health care and public policies have successfully reduced the mortality in children with SCD and has led to its evolution into a chronic disease in adults living with SCD. While management of SCD remains largely symptomatic with only one FDA-approved pharmacologic disease-modifying agent hydroxyurea, improved understanding of complex mechanisms underlying the pathophysiology of SCD is paving way for new therapies. In this chapter we review current disease-modifying therapies and supportive care for patients with SCD and briefly discuss pharmacologic agents currently under investigation. More... »

PAGES

65-86

Book

TITLE

Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

ISBN

978-3-319-62327-6
978-3-319-62328-3

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-62328-3_3

DOI

http://dx.doi.org/10.1007/978-3-319-62328-3_3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091881261


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