Non-infectious Diseases of the Oral Mucosa: The Importance of Immune Functions View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018-03-02

AUTHORS

Lesley Ann Bergmeier , Farida Fortune

ABSTRACT

Introduction: The non-microbial diseases of the oral mucosa constitute a heterogenous group of disorders from rare life-threatening autoimmune disorders such as Pemphigus vulgaris to more common conditions like recurrent aphthous stomatitis (RAS). However, they have some features in common; a genetic susceptibility or association in some; and immune dysregulation or immune-driven pathology in many. In this chapter, the diseases are briefly described in terms of any genetic susceptibility/association, and the contribution of the immune response to pathology. Many of the diseases are managed by using immunosuppressive drugs which also include specific monoclonal antibodies, the so-called biologics. The mode of action of some of the drugs most commonly used is outlined in Table 11.1. An extensive description of diagnostic criteria and detailed clinical management is beyond the scope of this chapter but is referenced in a literature review of current clinical management of oral mucosal disease in Chap. 10.1007/978-3-319-56065-6_12. More... »

PAGES

141-159

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-56065-6_11

DOI

http://dx.doi.org/10.1007/978-3-319-56065-6_11

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101292898


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Centre for Oral Immunology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, London, UK", 
          "id": "http://www.grid.ac/institutes/grid.4868.2", 
          "name": [
            "Centre for Oral Immunology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bergmeier", 
        "givenName": "Lesley Ann", 
        "id": "sg:person.01100261732.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100261732.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Oral Immunology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, London, UK", 
          "id": "http://www.grid.ac/institutes/grid.4868.2", 
          "name": [
            "Centre for Oral Immunology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fortune", 
        "givenName": "Farida", 
        "id": "sg:person.011016136005.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011016136005.53"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2018-03-02", 
    "datePublishedReg": "2018-03-02", 
    "description": "Introduction: The non-microbial diseases of the oral mucosa constitute a heterogenous group of disorders from rare life-threatening autoimmune disorders such as Pemphigus vulgaris to more common conditions like recurrent aphthous stomatitis (RAS). However, they have some features in common; a genetic susceptibility or association in some; and immune dysregulation or immune-driven pathology in many. In this chapter, the diseases are briefly described in terms of any genetic susceptibility/association, and the contribution of the immune response to pathology. Many of the diseases are managed by using immunosuppressive drugs which also include specific monoclonal antibodies, the so-called biologics. The mode of action of some of the drugs most commonly used is outlined in Table 11.1. An extensive description of diagnostic criteria and detailed clinical management is beyond the scope of this chapter but is referenced in a literature review of current clinical management of oral mucosal disease in Chap. 10.1007/978-3-319-56065-6_12.", 
    "editor": [
      {
        "familyName": "Bergmeier", 
        "givenName": "Lesley Ann", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-319-56065-6_11", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-319-56064-9", 
        "978-3-319-56065-6"
      ], 
      "name": "Oral Mucosa in Health and Disease", 
      "type": "Book"
    }, 
    "keywords": [
      "recurrent aphthous stomatitis", 
      "clinical management", 
      "oral mucosa", 
      "life-threatening autoimmune disorder", 
      "oral mucosal diseases", 
      "current clinical management", 
      "non-infectious diseases", 
      "immune dysregulation", 
      "aphthous stomatitis", 
      "autoimmune disorders", 
      "immunosuppressive drugs", 
      "mucosal disease", 
      "specific monoclonal antibodies", 
      "immune response", 
      "common condition", 
      "immune function", 
      "diagnostic criteria", 
      "heterogenous group", 
      "genetic susceptibility", 
      "disease", 
      "monoclonal antibodies", 
      "mode of action", 
      "mucosa", 
      "pathology", 
      "disorders", 
      "drugs", 
      "literature review", 
      "association", 
      "stomatitis", 
      "Table 11.1", 
      "antibodies", 
      "biologics", 
      "dysregulation", 
      "management", 
      "review", 
      "group", 
      "susceptibility", 
      "response", 
      "criteria", 
      "action", 
      "extensive description", 
      "function", 
      "importance", 
      "features", 
      "chapter", 
      "conditions", 
      "Chap", 
      "terms", 
      "contribution", 
      "scope", 
      "description", 
      "mode"
    ], 
    "name": "Non-infectious Diseases of the Oral Mucosa: The Importance of Immune Functions", 
    "pagination": "141-159", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1101292898"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-319-56065-6_11"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-319-56065-6_11", 
      "https://app.dimensions.ai/details/publication/pub.1101292898"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-06-01T22:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220601/entities/gbq_results/chapter/chapter_257.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-3-319-56065-6_11"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-56065-6_11'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-56065-6_11'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-56065-6_11'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-56065-6_11'


 

This table displays all metadata directly associated to this object as RDF triples.

119 TRIPLES      23 PREDICATES      76 URIs      69 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-319-56065-6_11 schema:about anzsrc-for:11
2 anzsrc-for:1107
3 schema:author N2de6ff5c40e24d42b2bf89209257fa33
4 schema:datePublished 2018-03-02
5 schema:datePublishedReg 2018-03-02
6 schema:description Introduction: The non-microbial diseases of the oral mucosa constitute a heterogenous group of disorders from rare life-threatening autoimmune disorders such as Pemphigus vulgaris to more common conditions like recurrent aphthous stomatitis (RAS). However, they have some features in common; a genetic susceptibility or association in some; and immune dysregulation or immune-driven pathology in many. In this chapter, the diseases are briefly described in terms of any genetic susceptibility/association, and the contribution of the immune response to pathology. Many of the diseases are managed by using immunosuppressive drugs which also include specific monoclonal antibodies, the so-called biologics. The mode of action of some of the drugs most commonly used is outlined in Table 11.1. An extensive description of diagnostic criteria and detailed clinical management is beyond the scope of this chapter but is referenced in a literature review of current clinical management of oral mucosal disease in Chap. 10.1007/978-3-319-56065-6_12.
7 schema:editor N62d60dc4cc4d4ca3912834f1d9b848ca
8 schema:genre chapter
9 schema:inLanguage en
10 schema:isAccessibleForFree false
11 schema:isPartOf N1d1c63854407486bbb2520d83f4c2cee
12 schema:keywords Chap
13 Table 11.1
14 action
15 antibodies
16 aphthous stomatitis
17 association
18 autoimmune disorders
19 biologics
20 chapter
21 clinical management
22 common condition
23 conditions
24 contribution
25 criteria
26 current clinical management
27 description
28 diagnostic criteria
29 disease
30 disorders
31 drugs
32 dysregulation
33 extensive description
34 features
35 function
36 genetic susceptibility
37 group
38 heterogenous group
39 immune dysregulation
40 immune function
41 immune response
42 immunosuppressive drugs
43 importance
44 life-threatening autoimmune disorder
45 literature review
46 management
47 mode
48 mode of action
49 monoclonal antibodies
50 mucosa
51 mucosal disease
52 non-infectious diseases
53 oral mucosa
54 oral mucosal diseases
55 pathology
56 recurrent aphthous stomatitis
57 response
58 review
59 scope
60 specific monoclonal antibodies
61 stomatitis
62 susceptibility
63 terms
64 schema:name Non-infectious Diseases of the Oral Mucosa: The Importance of Immune Functions
65 schema:pagination 141-159
66 schema:productId N2468bf93cc1643c6bbb40899ed95e1de
67 N7caec1a2fc394630bab7ea825237b8dd
68 schema:publisher N9b1dcd41fa5d4e1aadc69dc5b497ffd2
69 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101292898
70 https://doi.org/10.1007/978-3-319-56065-6_11
71 schema:sdDatePublished 2022-06-01T22:30
72 schema:sdLicense https://scigraph.springernature.com/explorer/license/
73 schema:sdPublisher Nde278956cd3243f8bafa8b387da06f8b
74 schema:url https://doi.org/10.1007/978-3-319-56065-6_11
75 sgo:license sg:explorer/license/
76 sgo:sdDataset chapters
77 rdf:type schema:Chapter
78 N0b3d6d222c6b4f53901bc341964761bf rdf:first sg:person.011016136005.53
79 rdf:rest rdf:nil
80 N1d1c63854407486bbb2520d83f4c2cee schema:isbn 978-3-319-56064-9
81 978-3-319-56065-6
82 schema:name Oral Mucosa in Health and Disease
83 rdf:type schema:Book
84 N1fe86420a21f4c6eb45b901e4e7f5bc8 schema:familyName Bergmeier
85 schema:givenName Lesley Ann
86 rdf:type schema:Person
87 N2468bf93cc1643c6bbb40899ed95e1de schema:name doi
88 schema:value 10.1007/978-3-319-56065-6_11
89 rdf:type schema:PropertyValue
90 N2de6ff5c40e24d42b2bf89209257fa33 rdf:first sg:person.01100261732.04
91 rdf:rest N0b3d6d222c6b4f53901bc341964761bf
92 N62d60dc4cc4d4ca3912834f1d9b848ca rdf:first N1fe86420a21f4c6eb45b901e4e7f5bc8
93 rdf:rest rdf:nil
94 N7caec1a2fc394630bab7ea825237b8dd schema:name dimensions_id
95 schema:value pub.1101292898
96 rdf:type schema:PropertyValue
97 N9b1dcd41fa5d4e1aadc69dc5b497ffd2 schema:name Springer Nature
98 rdf:type schema:Organisation
99 Nde278956cd3243f8bafa8b387da06f8b schema:name Springer Nature - SN SciGraph project
100 rdf:type schema:Organization
101 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
102 schema:name Medical and Health Sciences
103 rdf:type schema:DefinedTerm
104 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
105 schema:name Immunology
106 rdf:type schema:DefinedTerm
107 sg:person.01100261732.04 schema:affiliation grid-institutes:grid.4868.2
108 schema:familyName Bergmeier
109 schema:givenName Lesley Ann
110 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100261732.04
111 rdf:type schema:Person
112 sg:person.011016136005.53 schema:affiliation grid-institutes:grid.4868.2
113 schema:familyName Fortune
114 schema:givenName Farida
115 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011016136005.53
116 rdf:type schema:Person
117 grid-institutes:grid.4868.2 schema:alternateName Centre for Oral Immunology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, London, UK
118 schema:name Centre for Oral Immunology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, London, UK
119 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...