Role of PET/CT in Melanoma View Full Text


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Chapter Info

DATE

2017

AUTHORS

Michael S. Hofman , Rodney J. Hicks

ABSTRACT

In line with major advances in therapy for metastatic melanoma in the last decade, there have also been significant improvements in imaging. 18F-fluorodeoxyglucose (FDG) PET/CT has emerged as the imaging modality of choice for identifying locoregional nodal or distant metastatic disease and also for restaging following therapy. The spatial and contrast resolution of PET has improved owing to advances in both hardware and software reconstruction. The ultimate size of disease that PET can detect depends on how metabolically active the tumour cells are within an individual lesion. On a current generation PET/CT device, disease of 8 mm or greater in size is readily detected. In some patients, however, disease as small as 2–3 mm can be detected with confidence owing to the high metabolic activity of melanoma. More... »

PAGES

37-51

References to SciGraph publications

  • 2002-04. Evaluation of high-risk melanoma: comparison of [18F]FDG PET and high-dose 67Ga SPET in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2012-09. Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [18F]ICF01006, a highly promising melanoma PET tracer in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2009-11. Limited value of 18F-FDG PET/CT and S-100B tumour marker in the detection of liver metastases from uveal melanoma compared to liver metastases from cutaneous melanoma in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2012-03. The Additional Value of Lymphatic Mapping with Routine SPECT/CT in Unselected Patients with Clinically Localized Melanoma in ANNALS OF SURGICAL ONCOLOGY
  • 2008-10. Chemotherapy response assessment in stage IV melanoma patients—comparison of 18F-FDG-PET/CT, CT, brain MRI, and tumormarker S-100B in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2009-06. The Yield of SPECT/CT for Anatomical Lymphatic Mapping in Patients with Melanoma in ANNALS OF SURGICAL ONCOLOGY
  • 2013-09. Outcome of Clinical Stage III Melanoma Patients with FDG-PET and Whole-Body CT Added to the Diagnostic Workup in ANNALS OF SURGICAL ONCOLOGY
  • 2013-10. Clinical impact of 18F-FDG PET-CT in recurrent stage III/IV melanoma: a tertiary centre Specialist Skin Cancer Multidisciplinary Team (SSMDT) experience in INSIGHTS INTO IMAGING
  • 2011-05. PET/CT in malignant melanoma: contrast-enhanced CT versus plain low-dose CT in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Book

    TITLE

    PET/CT in Melanoma

    ISBN

    978-3-319-54740-4
    978-3-319-54741-1

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-319-54741-1_5

    DOI

    http://dx.doi.org/10.1007/978-3-319-54741-1_5

    DIMENSIONS

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