Mitochondrial DNA Damage in Autism View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Sarah Rose , Sarah Wong , Cecilia Giulivi

ABSTRACT

Mitochondria are organelles involved in essential roles in intermediary metabolism, perinatal neurodevelopment, immunity, bioenergetics, neurotransmitter metabolism, among other critical pathways. As such, mitochondrial dysfunction (MD) has deleterious effects with the potential of contributing to neurological diseases or enhancing their morbidity (e.g., autism and schizophrenia). Therefore, accumulation of mitochondrial damage is interpreted as a key element of the development of aging as well as neurodegenerative diseases. With the rise in the prevalence of autism spectrum disorders (ASD), there has been an increased interest in the etiology and contributors of this disorder. MD caused by genetics alone or by gene and environment interactions, may play a role in the etiology of ASD and holds promise for developing future therapies and/or interventions to help manage its symptoms or delaying its onset. Here we explore findings from our research and others analyzing the role of mitochondrial DNA damage as a contributor to ASD morbidity. More... »

PAGES

327-343

References to SciGraph publications

  • 2006-10. Fragile X syndrome and autism at the intersection of genetic and neural networks in NATURE NEUROSCIENCE
  • 2012-07. Association of GTF2i in the Williams-Beuren Syndrome Critical Region with Autism Spectrum Disorders in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2011-03. Brain Region-Specific Changes in Oxidative Stress and Neurotrophin Levels in Autism Spectrum Disorders (ASD) in THE CEREBELLUM
  • 2013-12. Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism in MOLECULAR AUTISM
  • 2000-06. The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2006-11. Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants in NATURE GENETICS
  • 2013-12. Focal brain inflammation and autism in JOURNAL OF NEUROINFLAMMATION
  • 2010-12. Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2011-06. Mitochondria in innate immune responses in NATURE REVIEWS IMMUNOLOGY
  • 2005-08. Gene targeting using zinc finger nucleases in NATURE BIOTECHNOLOGY
  • 2012-08. Diagnostic Yield of Chromosomal Microarray Analysis in an Autism Primary Care Practice: Which Guidelines to Implement? in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2012-07. Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain in TRANSLATIONAL PSYCHIATRY
  • 2008-11. The ketogenic diet: Uses in epilepsy and other neurologic illnesses in CURRENT TREATMENT OPTIONS IN NEUROLOGY
  • 2009-10. Mitochondrial DNA deletions of blood lymphocytes as genetic markers of low folate-related mitochondrial genotoxicity in peripheral tissues in EUROPEAN JOURNAL OF NUTRITION
  • 2009-09. Mitochondrial gene replacement in primate offspring and embryonic stem cells in NATURE
  • Book

    TITLE

    Biochemistry of Oxidative Stress

    ISBN

    978-3-319-45864-9
    978-3-319-45865-6

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-319-45865-6_21

    DOI

    http://dx.doi.org/10.1007/978-3-319-45865-6_21

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1040790371


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of California, Davis", 
              "id": "https://www.grid.ac/institutes/grid.27860.3b", 
              "name": [
                "Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rose", 
            "givenName": "Sarah", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, Davis", 
              "id": "https://www.grid.ac/institutes/grid.27860.3b", 
              "name": [
                "Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wong", 
            "givenName": "Sarah", 
            "id": "sg:person.01277374714.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277374714.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, Davis", 
              "id": "https://www.grid.ac/institutes/grid.27860.3b", 
              "name": [
                "Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis", 
                "Medical Investigations of Neurodevelopmental Disorders (MIND) Institute, University of California Davis"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Giulivi", 
            "givenName": "Cecilia", 
            "id": "sg:person.0701025676.91", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701025676.91"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/j.pediatrneurol.2007.02.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001090941"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0014-5793(98)01564-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001987161"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/schbul/sbq146", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002210145"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/088307380001500601", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002701526"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/088307380001500601", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002701526"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2008.07.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002754913"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2008.07.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002754913"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jpeds.2003.10.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002855445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.2010.1706", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003227353"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1523/jneurosci.5685-08.2009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003828658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-2952(02)01150-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003852305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-2952(02)01150-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003852305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4103/2319-4170.107152", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005027395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2006.04.064", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005103541"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-8749.2005.tb01113.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005200074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1469-8749.2005.tb01113.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005200074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1528-1167.2006.00439.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005582061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1528-1167.2006.00439.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005582061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11940-008-0043-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005668892", 
              "https://doi.org/10.1007/s11940-008-0043-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1289/ehp.8483", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006494666"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0401401101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006903643"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/0471142905.hg0812s74", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007888025"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2002-02-0522", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008607492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/08830738030180020501", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009498425"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/08830738030180020501", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009498425"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/dds124", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009978502"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddu057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010661071"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2010.11.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010684162"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-011-1389-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011373838", 
              "https://doi.org/10.1007/s10803-011-1389-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/embor.2011.157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011410773"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2013/609602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011727920"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jnr.20970", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011973548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2353/ajpath.2008.071163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012603132"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/jmg.40.10.e111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013003684"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/jmg.2004.024646", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013176159"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08368", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013205937", 
              "https://doi.org/10.1038/nature08368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08368", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013205937", 
              "https://doi.org/10.1038/nature08368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ejpn.2009.06.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013252590"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/hypertensionaha.111.172114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013593744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/hypertensionaha.111.172114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013593744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/hypertensionaha.111.172114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013593744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1471-4159.2011.07189.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014482167"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.nbd.2013.01.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017331905"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jns.2008.08.021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017482045"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.conb.2012.05.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017825271"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/jmg.40.8.e92", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019088831"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/07853890109002096", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019312274"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1542/peds.2013-1545", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020077530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/mus.20598", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020400212"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arcmed.2011.08.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021169299"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddq076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022024858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(11)61305-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022229807"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ana.10596", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022255537"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/humu.10257", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022546291"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/jnc.12646", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022645338"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbi.2012.07.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022762500"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/91.22.1922", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023170749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molmed.2010.04.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023533458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri2975", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023733273", 
              "https://doi.org/10.1038/nri2975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1742-2094-10-46", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024265323", 
              "https://doi.org/10.1186/1742-2094-10-46"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1125", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024455353", 
              "https://doi.org/10.1038/nbt1125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1125", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024455353", 
              "https://doi.org/10.1038/nbt1125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci22684", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025255907"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci22684", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025255907"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbi.2011.09.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025466109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cphy.c130008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026841040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.freeradbiomed.2012.03.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026925416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archgenpsychiatry.2011.76", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027280665"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.eplepsyres.2005.10.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027799433"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.08-128926", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028300126"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nn1765", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028583224", 
              "https://doi.org/10.1038/nn1765"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1289/ehp.1002728", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029100504"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2003.12.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029222778"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuron.2006.03.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030469327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuron.2006.03.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030469327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-011-1398-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031426926", 
              "https://doi.org/10.1007/s10803-011-1398-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-011-1398-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031426926", 
              "https://doi.org/10.1007/s10803-011-1398-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddq163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031611476"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0003815", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032435327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033903052", 
              "https://doi.org/10.1038/ng1897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033903052", 
              "https://doi.org/10.1038/ng1897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s0954579412000739", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034157189"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/2040-2392-4-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034893721", 
              "https://doi.org/10.1186/2040-2392-4-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0883073811429858", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035041244"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0883073811429858", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035041244"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/08830738020170101701", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035768358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/08830738020170101701", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035768358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/jmedgenet-2014-102803", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035865376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1005592401947", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036427450", 
              "https://doi.org/10.1023/a:1005592401947"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0045-6535(01)00239-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036725484"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/tp.2012.61", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038675626", 
              "https://doi.org/10.1038/tp.2012.61"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-010-1006-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039117642", 
              "https://doi.org/10.1007/s10803-010-1006-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-010-1006-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039117642", 
              "https://doi.org/10.1007/s10803-010-1006-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.coi.2011.11.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040055087"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj3480425", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040557727"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj3480425", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040557727"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jnutbio.2011.12.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040707487"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jnutbio.2011.12.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040707487"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-01-0191", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040713683"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ajmg.1477", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041545305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymgme.2009.11.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041558434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2012/986519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041911924"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1289/ehp.1104553", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043013931"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.peptides.2012.11.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043334833"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ana.20899", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043754085"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/circulationaha.104.524835", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044239501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.envint.2010.09.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045725699"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biopsych.2013.03.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045903725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fped.2014.00069", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046027060"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/toxsci/kfs339", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046297763"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cmet.2008.07.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046698800"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcp.1041360316", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046960572"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fphar.2012.00059", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046975972"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archpsyc.61.8.774", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047420515"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0911570106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047639669"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12311-010-0223-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048384621", 
              "https://doi.org/10.1007/s12311-010-0223-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1289/ehp.1003035", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048813169"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mcd.0b013e3283539fe5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048906074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mcd.0b013e3283539fe5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048906074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mcd.0b013e3283539fe5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048906074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0042504", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049070677"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.170.4.1964", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049372376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1471-4159.2004.02949.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049550170"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbi.2011.08.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049636367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molmed.2011.03.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050611147"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00394-009-0031-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050956437", 
              "https://doi.org/10.1007/s00394-009-0031-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00394-009-0031-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050956437", 
              "https://doi.org/10.1007/s00394-009-0031-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00394-009-0031-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050956437", 
              "https://doi.org/10.1007/s00394-009-0031-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/10715760310001621342", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052222948"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.plefa.2003.06.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053140184"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0883073813488668", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053171728"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0883073813488668", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053171728"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.289.1.49", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053720106"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/s0012162205000332", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054777227"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/es022197w", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055494545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/es022197w", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055494545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/ajh.2009.185", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056440685"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/377109", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058670203"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/377109", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058670203"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/appi.ajp.161.5.889", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063495919"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1176/appi.ajp.2009.09030361", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063498620"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1933719111410712", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064079093"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1933719111410712", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064079093"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000033795.17156.00", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064344729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000033795.17156.00", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064344729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000033795.17156.00", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064344729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1289/ehp.02110955", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064737739"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1289/ehp.6466", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064741830"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1542/peds.2015-1888", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1067831163"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074795166", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076819425", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.173.7.4286", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1076895573"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcn/80.6.1611", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1076976695"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078175045", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3760/cma.j.issn.1003-9406.2012.03.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1078574654"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078658899", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078771740", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2016", 
        "datePublishedReg": "2016-01-01", 
        "description": "Mitochondria are organelles involved in essential roles in intermediary metabolism, perinatal neurodevelopment, immunity, bioenergetics, neurotransmitter metabolism, among other critical pathways. As such, mitochondrial dysfunction (MD) has deleterious effects with the potential of contributing to neurological diseases or enhancing their morbidity (e.g., autism and schizophrenia). Therefore, accumulation of mitochondrial damage is interpreted as a key element of the development of aging as well as neurodegenerative diseases. With the rise in the prevalence of autism spectrum disorders (ASD), there has been an increased interest in the etiology and contributors of this disorder. MD caused by genetics alone or by gene and environment interactions, may play a role in the etiology of ASD and holds promise for developing future therapies and/or interventions to help manage its symptoms or delaying its onset. Here we explore findings from our research and others analyzing the role of mitochondrial DNA damage as a contributor to ASD morbidity.", 
        "editor": [
          {
            "familyName": "Gelpi", 
            "givenName": "Ricardo Jorge", 
            "type": "Person"
          }, 
          {
            "familyName": "Boveris", 
            "givenName": "Alberto", 
            "type": "Person"
          }, 
          {
            "familyName": "Poderoso", 
            "givenName": "Juan Jos\u00e9", 
            "type": "Person"
          }
        ], 
        "genre": "chapter", 
        "id": "sg:pub.10.1007/978-3-319-45865-6_21", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2504180", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4055561", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2436271", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2503863", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": {
          "isbn": [
            "978-3-319-45864-9", 
            "978-3-319-45865-6"
          ], 
          "name": "Biochemistry of Oxidative Stress", 
          "type": "Book"
        }, 
        "name": "Mitochondrial DNA Damage in Autism", 
        "pagination": "327-343", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/978-3-319-45865-6_21"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "c24f2bada50d0ed64ca4776b2462002d4aa9d1b7736a5435dc805f5f4d671a75"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1040790371"
            ]
          }
        ], 
        "publisher": {
          "location": "Cham", 
          "name": "Springer International Publishing", 
          "type": "Organisation"
        }, 
        "sameAs": [
          "https://doi.org/10.1007/978-3-319-45865-6_21", 
          "https://app.dimensions.ai/details/publication/pub.1040790371"
        ], 
        "sdDataset": "chapters", 
        "sdDatePublished": "2019-04-15T10:44", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000321.jsonl", 
        "type": "Chapter", 
        "url": "http://link.springer.com/10.1007/978-3-319-45865-6_21"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-45865-6_21'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-45865-6_21'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-45865-6_21'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-45865-6_21'


     

    This table displays all metadata directly associated to this object as RDF triples.

    491 TRIPLES      23 PREDICATES      155 URIs      20 LITERALS      8 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/978-3-319-45865-6_21 schema:about anzsrc-for:06
    2 anzsrc-for:0601
    3 schema:author N8d3be03ce77c4ca1b22ad192e578b4aa
    4 schema:citation sg:pub.10.1007/s00394-009-0031-0
    5 sg:pub.10.1007/s10803-010-1006-y
    6 sg:pub.10.1007/s10803-011-1389-4
    7 sg:pub.10.1007/s10803-011-1398-3
    8 sg:pub.10.1007/s11940-008-0043-8
    9 sg:pub.10.1007/s12311-010-0223-4
    10 sg:pub.10.1023/a:1005592401947
    11 sg:pub.10.1038/nature08368
    12 sg:pub.10.1038/nbt1125
    13 sg:pub.10.1038/ng1897
    14 sg:pub.10.1038/nn1765
    15 sg:pub.10.1038/nri2975
    16 sg:pub.10.1038/tp.2012.61
    17 sg:pub.10.1186/1742-2094-10-46
    18 sg:pub.10.1186/2040-2392-4-2
    19 https://app.dimensions.ai/details/publication/pub.1074795166
    20 https://app.dimensions.ai/details/publication/pub.1076819425
    21 https://app.dimensions.ai/details/publication/pub.1078175045
    22 https://app.dimensions.ai/details/publication/pub.1078658899
    23 https://app.dimensions.ai/details/publication/pub.1078771740
    24 https://doi.org/10.1001/archgenpsychiatry.2011.76
    25 https://doi.org/10.1001/archpsyc.61.8.774
    26 https://doi.org/10.1001/jama.2010.1706
    27 https://doi.org/10.1001/jama.289.1.49
    28 https://doi.org/10.1002/0471142905.hg0812s74
    29 https://doi.org/10.1002/ajmg.1477
    30 https://doi.org/10.1002/ana.10596
    31 https://doi.org/10.1002/ana.20899
    32 https://doi.org/10.1002/cphy.c130008
    33 https://doi.org/10.1002/humu.10257
    34 https://doi.org/10.1002/jcp.1041360316
    35 https://doi.org/10.1002/jnr.20970
    36 https://doi.org/10.1002/mus.20598
    37 https://doi.org/10.1016/j.ajhg.2008.07.004
    38 https://doi.org/10.1016/j.arcmed.2011.08.003
    39 https://doi.org/10.1016/j.bbi.2011.08.007
    40 https://doi.org/10.1016/j.bbi.2011.09.008
    41 https://doi.org/10.1016/j.bbi.2012.07.008
    42 https://doi.org/10.1016/j.biopsych.2013.03.006
    43 https://doi.org/10.1016/j.cmet.2008.07.006
    44 https://doi.org/10.1016/j.coi.2011.11.001
    45 https://doi.org/10.1016/j.conb.2012.05.004
    46 https://doi.org/10.1016/j.ejpn.2009.06.006
    47 https://doi.org/10.1016/j.envint.2010.09.001
    48 https://doi.org/10.1016/j.eplepsyres.2005.10.003
    49 https://doi.org/10.1016/j.febslet.2006.04.064
    50 https://doi.org/10.1016/j.freeradbiomed.2012.03.011
    51 https://doi.org/10.1016/j.jns.2008.08.021
    52 https://doi.org/10.1016/j.jnutbio.2011.12.008
    53 https://doi.org/10.1016/j.jpeds.2003.10.023
    54 https://doi.org/10.1016/j.molmed.2010.04.007
    55 https://doi.org/10.1016/j.molmed.2011.03.001
    56 https://doi.org/10.1016/j.nbd.2013.01.006
    57 https://doi.org/10.1016/j.neuron.2006.03.023
    58 https://doi.org/10.1016/j.pediatrneurol.2007.02.008
    59 https://doi.org/10.1016/j.peptides.2012.11.005
    60 https://doi.org/10.1016/j.plefa.2003.06.003
    61 https://doi.org/10.1016/j.ymgme.2003.12.008
    62 https://doi.org/10.1016/j.ymgme.2009.11.005
    63 https://doi.org/10.1016/j.ymgme.2010.11.001
    64 https://doi.org/10.1016/s0006-2952(02)01150-4
    65 https://doi.org/10.1016/s0014-5793(98)01564-6
    66 https://doi.org/10.1016/s0045-6535(01)00239-9
    67 https://doi.org/10.1016/s0140-6736(11)61305-6
    68 https://doi.org/10.1017/s0012162205000332
    69 https://doi.org/10.1017/s0954579412000739
    70 https://doi.org/10.1021/es022197w
    71 https://doi.org/10.1038/ajh.2009.185
    72 https://doi.org/10.1038/embor.2011.157
    73 https://doi.org/10.1042/bj3480425
    74 https://doi.org/10.1073/pnas.0401401101
    75 https://doi.org/10.1073/pnas.0911570106
    76 https://doi.org/10.1080/10715760310001621342
    77 https://doi.org/10.1086/377109
    78 https://doi.org/10.1093/ajcn/80.6.1611
    79 https://doi.org/10.1093/hmg/ddq076
    80 https://doi.org/10.1093/hmg/ddq163
    81 https://doi.org/10.1093/hmg/dds124
    82 https://doi.org/10.1093/hmg/ddu057
    83 https://doi.org/10.1093/jnci/91.22.1922
    84 https://doi.org/10.1093/schbul/sbq146
    85 https://doi.org/10.1093/toxsci/kfs339
    86 https://doi.org/10.1096/fj.08-128926
    87 https://doi.org/10.1097/mcd.0b013e3283539fe5
    88 https://doi.org/10.1111/j.1469-8749.2005.tb01113.x
    89 https://doi.org/10.1111/j.1471-4159.2004.02949.x
    90 https://doi.org/10.1111/j.1471-4159.2011.07189.x
    91 https://doi.org/10.1111/j.1528-1167.2006.00439.x
    92 https://doi.org/10.1111/jnc.12646
    93 https://doi.org/10.1136/jmedgenet-2014-102803
    94 https://doi.org/10.1136/jmg.2004.024646
    95 https://doi.org/10.1136/jmg.40.10.e111
    96 https://doi.org/10.1136/jmg.40.8.e92
    97 https://doi.org/10.1155/2012/986519
    98 https://doi.org/10.1155/2013/609602
    99 https://doi.org/10.1161/circulationaha.104.524835
    100 https://doi.org/10.1161/hypertensionaha.111.172114
    101 https://doi.org/10.1172/jci22684
    102 https://doi.org/10.1176/appi.ajp.161.5.889
    103 https://doi.org/10.1176/appi.ajp.2009.09030361
    104 https://doi.org/10.1177/088307380001500601
    105 https://doi.org/10.1177/08830738020170101701
    106 https://doi.org/10.1177/08830738030180020501
    107 https://doi.org/10.1177/0883073811429858
    108 https://doi.org/10.1177/0883073813488668
    109 https://doi.org/10.1177/1933719111410712
    110 https://doi.org/10.1182/blood-2002-02-0522
    111 https://doi.org/10.1182/blood-2004-01-0191
    112 https://doi.org/10.1212/01.wnl.0000033795.17156.00
    113 https://doi.org/10.1289/ehp.02110955
    114 https://doi.org/10.1289/ehp.1002728
    115 https://doi.org/10.1289/ehp.1003035
    116 https://doi.org/10.1289/ehp.1104553
    117 https://doi.org/10.1289/ehp.6466
    118 https://doi.org/10.1289/ehp.8483
    119 https://doi.org/10.1371/journal.pone.0003815
    120 https://doi.org/10.1371/journal.pone.0042504
    121 https://doi.org/10.1523/jneurosci.5685-08.2009
    122 https://doi.org/10.1542/peds.2013-1545
    123 https://doi.org/10.1542/peds.2015-1888
    124 https://doi.org/10.2353/ajpath.2008.071163
    125 https://doi.org/10.3109/07853890109002096
    126 https://doi.org/10.3389/fped.2014.00069
    127 https://doi.org/10.3389/fphar.2012.00059
    128 https://doi.org/10.3760/cma.j.issn.1003-9406.2012.03.004
    129 https://doi.org/10.4049/jimmunol.170.4.1964
    130 https://doi.org/10.4049/jimmunol.173.7.4286
    131 https://doi.org/10.4103/2319-4170.107152
    132 schema:datePublished 2016
    133 schema:datePublishedReg 2016-01-01
    134 schema:description Mitochondria are organelles involved in essential roles in intermediary metabolism, perinatal neurodevelopment, immunity, bioenergetics, neurotransmitter metabolism, among other critical pathways. As such, mitochondrial dysfunction (MD) has deleterious effects with the potential of contributing to neurological diseases or enhancing their morbidity (e.g., autism and schizophrenia). Therefore, accumulation of mitochondrial damage is interpreted as a key element of the development of aging as well as neurodegenerative diseases. With the rise in the prevalence of autism spectrum disorders (ASD), there has been an increased interest in the etiology and contributors of this disorder. MD caused by genetics alone or by gene and environment interactions, may play a role in the etiology of ASD and holds promise for developing future therapies and/or interventions to help manage its symptoms or delaying its onset. Here we explore findings from our research and others analyzing the role of mitochondrial DNA damage as a contributor to ASD morbidity.
    135 schema:editor N41d6d2ab212e45169e327a452cb24db6
    136 schema:genre chapter
    137 schema:inLanguage en
    138 schema:isAccessibleForFree false
    139 schema:isPartOf N1513a8dead354cc1ae0db7fe6d979cb1
    140 schema:name Mitochondrial DNA Damage in Autism
    141 schema:pagination 327-343
    142 schema:productId N6890165b13744b2c81d96652c1d5a444
    143 Nad50eaba3fa84f0ab3faa1909ff6998f
    144 Ne482ec7ffc104dd58b2bdedac2625a20
    145 schema:publisher N5ffbf43adb0249209fba3ccabad4ed70
    146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040790371
    147 https://doi.org/10.1007/978-3-319-45865-6_21
    148 schema:sdDatePublished 2019-04-15T10:44
    149 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    150 schema:sdPublisher N64770649c6234526badb3a91e1d1859c
    151 schema:url http://link.springer.com/10.1007/978-3-319-45865-6_21
    152 sgo:license sg:explorer/license/
    153 sgo:sdDataset chapters
    154 rdf:type schema:Chapter
    155 N1513a8dead354cc1ae0db7fe6d979cb1 schema:isbn 978-3-319-45864-9
    156 978-3-319-45865-6
    157 schema:name Biochemistry of Oxidative Stress
    158 rdf:type schema:Book
    159 N1d6f2a8e7eb344bb82f503687eea42fd schema:familyName Boveris
    160 schema:givenName Alberto
    161 rdf:type schema:Person
    162 N41d6d2ab212e45169e327a452cb24db6 rdf:first N48bcf5cc505148a3a6b28d4f9c580a6c
    163 rdf:rest Nd1a523f581fd49ddab138bc677014e1d
    164 N450875d3581d4a6492f112c9c4ae0078 rdf:first sg:person.01277374714.23
    165 rdf:rest Nf560c746e4ae4367be5280f8fbbd6e4b
    166 N48bcf5cc505148a3a6b28d4f9c580a6c schema:familyName Gelpi
    167 schema:givenName Ricardo Jorge
    168 rdf:type schema:Person
    169 N5ffbf43adb0249209fba3ccabad4ed70 schema:location Cham
    170 schema:name Springer International Publishing
    171 rdf:type schema:Organisation
    172 N64770649c6234526badb3a91e1d1859c schema:name Springer Nature - SN SciGraph project
    173 rdf:type schema:Organization
    174 N6890165b13744b2c81d96652c1d5a444 schema:name readcube_id
    175 schema:value c24f2bada50d0ed64ca4776b2462002d4aa9d1b7736a5435dc805f5f4d671a75
    176 rdf:type schema:PropertyValue
    177 N7f08957c3a1846e9a7cab2e235288ce8 rdf:first N8c7a02212245411591dec2d8dbd02492
    178 rdf:rest rdf:nil
    179 N8c7a02212245411591dec2d8dbd02492 schema:familyName Poderoso
    180 schema:givenName Juan José
    181 rdf:type schema:Person
    182 N8d3be03ce77c4ca1b22ad192e578b4aa rdf:first Nd2a787a39c7b46d48989c0911a85a98c
    183 rdf:rest N450875d3581d4a6492f112c9c4ae0078
    184 Nad50eaba3fa84f0ab3faa1909ff6998f schema:name doi
    185 schema:value 10.1007/978-3-319-45865-6_21
    186 rdf:type schema:PropertyValue
    187 Nd1a523f581fd49ddab138bc677014e1d rdf:first N1d6f2a8e7eb344bb82f503687eea42fd
    188 rdf:rest N7f08957c3a1846e9a7cab2e235288ce8
    189 Nd2a787a39c7b46d48989c0911a85a98c schema:affiliation https://www.grid.ac/institutes/grid.27860.3b
    190 schema:familyName Rose
    191 schema:givenName Sarah
    192 rdf:type schema:Person
    193 Ne482ec7ffc104dd58b2bdedac2625a20 schema:name dimensions_id
    194 schema:value pub.1040790371
    195 rdf:type schema:PropertyValue
    196 Nf560c746e4ae4367be5280f8fbbd6e4b rdf:first sg:person.0701025676.91
    197 rdf:rest rdf:nil
    198 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    199 schema:name Biological Sciences
    200 rdf:type schema:DefinedTerm
    201 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    202 schema:name Biochemistry and Cell Biology
    203 rdf:type schema:DefinedTerm
    204 sg:grant.2436271 http://pending.schema.org/fundedItem sg:pub.10.1007/978-3-319-45865-6_21
    205 rdf:type schema:MonetaryGrant
    206 sg:grant.2503863 http://pending.schema.org/fundedItem sg:pub.10.1007/978-3-319-45865-6_21
    207 rdf:type schema:MonetaryGrant
    208 sg:grant.2504180 http://pending.schema.org/fundedItem sg:pub.10.1007/978-3-319-45865-6_21
    209 rdf:type schema:MonetaryGrant
    210 sg:grant.4055561 http://pending.schema.org/fundedItem sg:pub.10.1007/978-3-319-45865-6_21
    211 rdf:type schema:MonetaryGrant
    212 sg:person.01277374714.23 schema:affiliation https://www.grid.ac/institutes/grid.27860.3b
    213 schema:familyName Wong
    214 schema:givenName Sarah
    215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277374714.23
    216 rdf:type schema:Person
    217 sg:person.0701025676.91 schema:affiliation https://www.grid.ac/institutes/grid.27860.3b
    218 schema:familyName Giulivi
    219 schema:givenName Cecilia
    220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701025676.91
    221 rdf:type schema:Person
    222 sg:pub.10.1007/s00394-009-0031-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050956437
    223 https://doi.org/10.1007/s00394-009-0031-0
    224 rdf:type schema:CreativeWork
    225 sg:pub.10.1007/s10803-010-1006-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1039117642
    226 https://doi.org/10.1007/s10803-010-1006-y
    227 rdf:type schema:CreativeWork
    228 sg:pub.10.1007/s10803-011-1389-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011373838
    229 https://doi.org/10.1007/s10803-011-1389-4
    230 rdf:type schema:CreativeWork
    231 sg:pub.10.1007/s10803-011-1398-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031426926
    232 https://doi.org/10.1007/s10803-011-1398-3
    233 rdf:type schema:CreativeWork
    234 sg:pub.10.1007/s11940-008-0043-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005668892
    235 https://doi.org/10.1007/s11940-008-0043-8
    236 rdf:type schema:CreativeWork
    237 sg:pub.10.1007/s12311-010-0223-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048384621
    238 https://doi.org/10.1007/s12311-010-0223-4
    239 rdf:type schema:CreativeWork
    240 sg:pub.10.1023/a:1005592401947 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036427450
    241 https://doi.org/10.1023/a:1005592401947
    242 rdf:type schema:CreativeWork
    243 sg:pub.10.1038/nature08368 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013205937
    244 https://doi.org/10.1038/nature08368
    245 rdf:type schema:CreativeWork
    246 sg:pub.10.1038/nbt1125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024455353
    247 https://doi.org/10.1038/nbt1125
    248 rdf:type schema:CreativeWork
    249 sg:pub.10.1038/ng1897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033903052
    250 https://doi.org/10.1038/ng1897
    251 rdf:type schema:CreativeWork
    252 sg:pub.10.1038/nn1765 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028583224
    253 https://doi.org/10.1038/nn1765
    254 rdf:type schema:CreativeWork
    255 sg:pub.10.1038/nri2975 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023733273
    256 https://doi.org/10.1038/nri2975
    257 rdf:type schema:CreativeWork
    258 sg:pub.10.1038/tp.2012.61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038675626
    259 https://doi.org/10.1038/tp.2012.61
    260 rdf:type schema:CreativeWork
    261 sg:pub.10.1186/1742-2094-10-46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024265323
    262 https://doi.org/10.1186/1742-2094-10-46
    263 rdf:type schema:CreativeWork
    264 sg:pub.10.1186/2040-2392-4-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034893721
    265 https://doi.org/10.1186/2040-2392-4-2
    266 rdf:type schema:CreativeWork
    267 https://app.dimensions.ai/details/publication/pub.1074795166 schema:CreativeWork
    268 https://app.dimensions.ai/details/publication/pub.1076819425 schema:CreativeWork
    269 https://app.dimensions.ai/details/publication/pub.1078175045 schema:CreativeWork
    270 https://app.dimensions.ai/details/publication/pub.1078658899 schema:CreativeWork
    271 https://app.dimensions.ai/details/publication/pub.1078771740 schema:CreativeWork
    272 https://doi.org/10.1001/archgenpsychiatry.2011.76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027280665
    273 rdf:type schema:CreativeWork
    274 https://doi.org/10.1001/archpsyc.61.8.774 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047420515
    275 rdf:type schema:CreativeWork
    276 https://doi.org/10.1001/jama.2010.1706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003227353
    277 rdf:type schema:CreativeWork
    278 https://doi.org/10.1001/jama.289.1.49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053720106
    279 rdf:type schema:CreativeWork
    280 https://doi.org/10.1002/0471142905.hg0812s74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007888025
    281 rdf:type schema:CreativeWork
    282 https://doi.org/10.1002/ajmg.1477 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041545305
    283 rdf:type schema:CreativeWork
    284 https://doi.org/10.1002/ana.10596 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022255537
    285 rdf:type schema:CreativeWork
    286 https://doi.org/10.1002/ana.20899 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043754085
    287 rdf:type schema:CreativeWork
    288 https://doi.org/10.1002/cphy.c130008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026841040
    289 rdf:type schema:CreativeWork
    290 https://doi.org/10.1002/humu.10257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022546291
    291 rdf:type schema:CreativeWork
    292 https://doi.org/10.1002/jcp.1041360316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046960572
    293 rdf:type schema:CreativeWork
    294 https://doi.org/10.1002/jnr.20970 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011973548
    295 rdf:type schema:CreativeWork
    296 https://doi.org/10.1002/mus.20598 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020400212
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.1016/j.ajhg.2008.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002754913
    299 rdf:type schema:CreativeWork
    300 https://doi.org/10.1016/j.arcmed.2011.08.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021169299
    301 rdf:type schema:CreativeWork
    302 https://doi.org/10.1016/j.bbi.2011.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049636367
    303 rdf:type schema:CreativeWork
    304 https://doi.org/10.1016/j.bbi.2011.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025466109
    305 rdf:type schema:CreativeWork
    306 https://doi.org/10.1016/j.bbi.2012.07.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022762500
    307 rdf:type schema:CreativeWork
    308 https://doi.org/10.1016/j.biopsych.2013.03.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045903725
    309 rdf:type schema:CreativeWork
    310 https://doi.org/10.1016/j.cmet.2008.07.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046698800
    311 rdf:type schema:CreativeWork
    312 https://doi.org/10.1016/j.coi.2011.11.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040055087
    313 rdf:type schema:CreativeWork
    314 https://doi.org/10.1016/j.conb.2012.05.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017825271
    315 rdf:type schema:CreativeWork
    316 https://doi.org/10.1016/j.ejpn.2009.06.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013252590
    317 rdf:type schema:CreativeWork
    318 https://doi.org/10.1016/j.envint.2010.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045725699
    319 rdf:type schema:CreativeWork
    320 https://doi.org/10.1016/j.eplepsyres.2005.10.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027799433
    321 rdf:type schema:CreativeWork
    322 https://doi.org/10.1016/j.febslet.2006.04.064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005103541
    323 rdf:type schema:CreativeWork
    324 https://doi.org/10.1016/j.freeradbiomed.2012.03.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026925416
    325 rdf:type schema:CreativeWork
    326 https://doi.org/10.1016/j.jns.2008.08.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017482045
    327 rdf:type schema:CreativeWork
    328 https://doi.org/10.1016/j.jnutbio.2011.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040707487
    329 rdf:type schema:CreativeWork
    330 https://doi.org/10.1016/j.jpeds.2003.10.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002855445
    331 rdf:type schema:CreativeWork
    332 https://doi.org/10.1016/j.molmed.2010.04.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023533458
    333 rdf:type schema:CreativeWork
    334 https://doi.org/10.1016/j.molmed.2011.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050611147
    335 rdf:type schema:CreativeWork
    336 https://doi.org/10.1016/j.nbd.2013.01.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017331905
    337 rdf:type schema:CreativeWork
    338 https://doi.org/10.1016/j.neuron.2006.03.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030469327
    339 rdf:type schema:CreativeWork
    340 https://doi.org/10.1016/j.pediatrneurol.2007.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001090941
    341 rdf:type schema:CreativeWork
    342 https://doi.org/10.1016/j.peptides.2012.11.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043334833
    343 rdf:type schema:CreativeWork
    344 https://doi.org/10.1016/j.plefa.2003.06.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053140184
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1016/j.ymgme.2003.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029222778
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1016/j.ymgme.2009.11.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041558434
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1016/j.ymgme.2010.11.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010684162
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1016/s0006-2952(02)01150-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003852305
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.1016/s0014-5793(98)01564-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001987161
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.1016/s0045-6535(01)00239-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036725484
    357 rdf:type schema:CreativeWork
    358 https://doi.org/10.1016/s0140-6736(11)61305-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022229807
    359 rdf:type schema:CreativeWork
    360 https://doi.org/10.1017/s0012162205000332 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054777227
    361 rdf:type schema:CreativeWork
    362 https://doi.org/10.1017/s0954579412000739 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034157189
    363 rdf:type schema:CreativeWork
    364 https://doi.org/10.1021/es022197w schema:sameAs https://app.dimensions.ai/details/publication/pub.1055494545
    365 rdf:type schema:CreativeWork
    366 https://doi.org/10.1038/ajh.2009.185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056440685
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1038/embor.2011.157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011410773
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1042/bj3480425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040557727
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1073/pnas.0401401101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006903643
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1073/pnas.0911570106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047639669
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1080/10715760310001621342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052222948
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1086/377109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058670203
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1093/ajcn/80.6.1611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076976695
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1093/hmg/ddq076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022024858
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1093/hmg/ddq163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031611476
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1093/hmg/dds124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009978502
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1093/hmg/ddu057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010661071
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1093/jnci/91.22.1922 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023170749
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1093/schbul/sbq146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002210145
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1093/toxsci/kfs339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046297763
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1096/fj.08-128926 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028300126
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1097/mcd.0b013e3283539fe5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048906074
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1111/j.1469-8749.2005.tb01113.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005200074
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1111/j.1471-4159.2004.02949.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049550170
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1111/j.1471-4159.2011.07189.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014482167
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1111/j.1528-1167.2006.00439.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005582061
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1111/jnc.12646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022645338
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1136/jmedgenet-2014-102803 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035865376
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1136/jmg.2004.024646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013176159
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1136/jmg.40.10.e111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013003684
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1136/jmg.40.8.e92 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019088831
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1155/2012/986519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041911924
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1155/2013/609602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011727920
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1161/circulationaha.104.524835 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044239501
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1161/hypertensionaha.111.172114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013593744
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1172/jci22684 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025255907
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1176/appi.ajp.161.5.889 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063495919
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1176/appi.ajp.2009.09030361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063498620
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1177/088307380001500601 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002701526
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1177/08830738020170101701 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035768358
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1177/08830738030180020501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009498425
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1177/0883073811429858 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035041244
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1177/0883073813488668 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053171728
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1177/1933719111410712 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064079093
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1182/blood-2002-02-0522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008607492
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1182/blood-2004-01-0191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040713683
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1212/01.wnl.0000033795.17156.00 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064344729
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1289/ehp.02110955 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064737739
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1289/ehp.1002728 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029100504
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1289/ehp.1003035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048813169
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1289/ehp.1104553 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043013931
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1289/ehp.6466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064741830
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1289/ehp.8483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006494666
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1371/journal.pone.0003815 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032435327
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1371/journal.pone.0042504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049070677
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1523/jneurosci.5685-08.2009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003828658
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1542/peds.2013-1545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020077530
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1542/peds.2015-1888 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067831163
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.2353/ajpath.2008.071163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012603132
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.3109/07853890109002096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019312274
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.3389/fped.2014.00069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046027060
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.3389/fphar.2012.00059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046975972
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.3760/cma.j.issn.1003-9406.2012.03.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078574654
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.4049/jimmunol.170.4.1964 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049372376
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.4049/jimmunol.173.7.4286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076895573
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.4103/2319-4170.107152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005027395
    487 rdf:type schema:CreativeWork
    488 https://www.grid.ac/institutes/grid.27860.3b schema:alternateName University of California, Davis
    489 schema:name Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis
    490 Medical Investigations of Neurodevelopmental Disorders (MIND) Institute, University of California Davis
    491 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...